J Korean Acad Oral Health.
2014 Jun;38(2):90-94.
Effect of bamboo salt on human gingival fibroblasts
- Affiliations
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- 1Dental Hygiene, Wonkwang Health Science University, Chonnam National University School of Dentistry, Gwanju, Korea.
- 2Department of Preventive & Public Health Dentistry, Chonnam National University School of Dentistry, Gwanju, Korea. hochoi@chonnam.ac.kr
- 3Dental Science Research Institute, Chonnam National University School of Dentistry, Gwanju, Korea.
Abstract
- OBJECTIVES: To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt.
METHODS
Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1beta and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction.
RESULTS
Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1beta secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration.
CONCLUSIONS
The above results suggest that bamboo salt inhibits the release of IL-1beta and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
Keyword
- Bamboo salt; Human gingival fibroblast; IL-1beta; IL-6
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