- Interleukin-1beta Participates in the Development of Pneumococcal Acute Lung Injury and Death by Promoting Alveolar Microvascular Leakage
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Bong Y, Shin SG, Koh SH, Lim JH
- KMID: 2149209
- J Bacteriol Virol.
- 2015 Jun;45(2):93-103.
- doi: 10.4167/jbv.2015.45.2.93
Streptococcus pneumoniae (S. pneumoniae, also known as pneumococcus) infections are major causes of death worldwide. Despite the development and use of effective antibiotics, high, early mortality due to pneumococcal infections... -
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- Caspase-1 Independent Viral Clearance and Adaptive Immunity Against Mucosal Respiratory Syncytial Virus Infection
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Shim YR, Lee HK
- KMID: 2168032
- Immune Netw.
- 2015 Apr;15(2):73-82.
- doi: 10.4110/in.2015.15.2.73
Respiratory syncytial virus (RSV) infection is recognized by the innate immune system through Toll like receptors (TLRs) and retinoic acid inducible gene I. These pathways lead to the activation of... -
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- Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
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Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE
- KMID: 2352817
- Yonsei Med J.
- 2015 Jan;56(1):277-286.
- doi: 10.3349/ymj.2015.56.1.277
PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs... -
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- Effect of bamboo salt on human gingival fibroblasts
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Oh HN, Choi CH
- KMID: 2321445
- J Korean Acad Oral Health.
- 2014 Jun;38(2):90-94.
OBJECTIVES: To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt. METHODS: Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion... -
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- Nuclear Factor-kappaB Dependent Induction of TNF-alpha and IL-1beta by the Aggregatibacter actinomycetemcomitans Lipopolysaccharide in RAW 264.7 Cells
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Na HS, Jeong SY, Park MH, Kim S, Chung J
- KMID: 1703487
- Int J Oral Biol.
- 2014 Mar;39(1):15-22.
Aggregatibacter actinomycetemcomitans is an important pathogen in the development of localized aggressive periodontitis. Lipopolysaccharide (LPS) is a virulent factor of periodontal pathogens that contributes to alveolar bone loss and connective... -
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- alpha-Asarone Ameliorates Memory Deficit in Lipopolysaccharide-Treated Mice via Suppression of Pro-Inflammatory Cytokines and Microglial Activation
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Shin JW, Cheong YJ, Koo YM, Kim S, Noh CK, Son YH, Kang C, Sohn NW
- KMID: 2048326
- Biomol Ther.
- 2014 Jan;22(1):17-26.
alpha-Asarone exhibits a number of pharmacological actions including neuroprotective, anti-oxidative, anticonvulsive, and cognitive enhancing action. The present study investigated the effects of alpha-asarone on pro-inflammatory cytokines mRNA, microglial activation, and... -
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- The Effect of Agmatine on Expression of IL-1beta and TLX Which Promotes Neuronal Differentiation in Lipopolysaccharide-Treated Neural Progenitors
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Song J, Kumar BK, Kang S, Park KA, Lee WT, Lee JE
- KMID: 2284630
- Exp Neurobiol.
- 2013 Dec;22(4):268-276.
- doi: 10.5607/en.2013.22.4.268
Differentiation of neural progenitor cells (NPCs) is important for protecting neural cells and brain tissue during inflammation. Interleukin-1 beta (IL-1beta) is the most common pro- inflammatory cytokine in brain inflammation,... -
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- Transglutaminase-2 Is Involved in Expression of Osteoprotegerin in MG-63 Osteosarcoma Cells
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Lee HJ, Lee CH
- KMID: 1502488
- Biomol Ther.
- 2013 May;21(3):204-209.
Osteoprotegerin (OPG) is a secreted glycoprotein and a member of the tumor necrosis factor receptor superfamily. It usually functions in bone remodeling, by inhibiting osteoclastogenesis through interaction with a receptor... -
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- Effects of freeze-dried cranberry powder on serum lipids and inflammatory markers in lipopolysaccharide treated rats fed an atherogenic diet
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Kim MJ, Ohn J, Kim JH, Kwak HK
- KMID: 2313545
- Nutr Res Pract.
- 2011 Oct;5(5):404-411.
This study investigated the effects of freeze-dried cranberry powder on anti-inflammation and lipid profiles of lipopolysaccharide (LPS)-treated rats fed an atherogenic diet for 6 weeks. Forty Sprague-Dawley male rats (6-weeks-old)... -
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- Pyrin Domain (PYD)-containing Inflammasome in Innate Immunity
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Hong S, Park S, Yu JW
- KMID: 1449888
- J Bacteriol Virol.
- 2011 Sep;41(3):133-146.
- doi: 10.4167/jbv.2011.41.3.133
Inflammasome is a cytosolic multiprotein complex to activate caspase-1 leading to the subsequent processing of inactive pro-interleukin-1-beta (Pro-IL-1beta) into its active interleukin-1 beta (IL-1beta) in response to pathogen- or danger-associated... -
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- Expression of TNF-alpha and IL-1beta in Splenic Dendritic Cells and Their Serum Levels in Mouse Sparganosis
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Yang HJ
- KMID: 1090623
- Korean J Parasitol.
- 2011 Jun;49(2):191-194.
- doi: 10.3347/kjp.2011.49.2.191
Sparganosis is a tissue invading helminthiasis infecting intermediate hosts, including humans. Strong immune responses are expected to occur in early phases of infection. Thus, we investigated cytokine expressions in splenic... -
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- Characterization and Immunopotentiating Effects of the Glycoprotein Isolated from Dioscorea Batatas
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Huong PT, Lee CH, Li MH, Lee MY, Kim JK, Lee SM, Seon JH, Lee DC, Jeon YJ
- KMID: 2285414
- Korean J Physiol Pharmacol.
- 2011 Apr;15(2):101-106.
- doi: 10.4196/kjpp.2011.15.2.101
We demonstrate that glycoprotein isolated from Dioscorea batatas (GDB) has immunostimulatory effects including macrophage activation. Analysis of infiltration of inflammatory cells into peritoneal cavity showed GDB treatment significantly increased the... -
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- Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy
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Kim C, Kim DG, Park SH, Hwang YI, Jang SH, Kim CH, Jung KS, Min K, Lee JW, Jang YS
- KMID: 1106437
- Yonsei Med J.
- 2011 Jan;52(1):51-58.
- doi: 10.3349/ymj.2011.52.1.51
PURPOSE: Tuberculous pleurisy is the most frequent extrapulmonary manifestation of tuberculosis. In spite of adequate treatment, pleural fibrosis is a common complication, but the mechanism has not been elucidated. This... -
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- Glucocorticoid Mechanism of Inhibition of the Inflammatory Cells in Lumbar Intervertebral Disc Cells Stimulated by TNF-alpha Production of Nuclear Factor-kappaB
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Oh IS, Park SE, Son JM, Chung JY, Kim YY
- KMID: 1455857
- J Korean Orthop Res Soc.
- 2010 Dec;13(2):80-87.
PURPOSE: To analyze the action mechanism of NF-kappaB, IkappaB-alpha and effect of the Dexamethasone (DEXA) in mediating this inflammation, after stimulating cultured herniated intervertebral disc cells with TNF-alpha. MATERIALS AND METHODS:... -
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- Evaluation of osteogenic activity of periosteal-derived cells treated with inflammatory cytokines
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Park BW, Choi MJ, Hah YS, Cho HY, Kim DR, Kim UK, Kang HJ, Kim JR, Byun JH
- KMID: 2328497
- J Korean Assoc Oral Maxillofac Surg.
- 2010 Oct;36(5):341-345.
INTRODUCTION: Skeletal homeostasis is normally maintained by the stability between bone formation by osteoblasts and bone resorption by osteoclasts. However, the correlation between the inflammatory reaction and osteoblastic differentiation of... -
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- The Effect of ER:YAG Laser & ER,CR:YSGG Laser on the Tissue of the Inflammation-Induced Mouse
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Park TI, Lee HS, Lee HJ, Chae CH, Lee YJ, Byeon KS, Hong SM, Choi MR, Park JW
- KMID: 2044713
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2010 Sep;32(5):396-405.
PURPOSE: This study was performed to find out the effects of the Er:YAG laser (Key Laser) & Er,Cr:YSGG laser (Water Laser) on inflammatory tissues. MATERIALS AND METHODS: It was performed on... -
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- Effects of Plant Water Extract Codonopsis Lanceolatae on Mouse Immune Cell Activation Ex Vivo
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Ryu HS, Kim KO, Kim HS
- KMID: 2264720
- Korean J Nutr.
- 2009 Apr;42(3):207-212.
- doi: 10.4163/kjn.2009.42.3.207
Codonopsis lanceolatae has been used as one of the traditional remedies as well as food source. However, few studies on their immunomodulating effects have been reported. We previously reported that... -
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- The Central and Peripheral Production of Pro-inflammatory Cytokine, IL-1b after Immune and Stress Stimulation in Rats
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Jung EY, Kim KS, Shim I
- KMID: 2165282
- Exp Neurobiol.
- 2008 Dec;17(2):47-54.
- doi: 10.5607/en.2008.17.2.47
Interleukin-1beta (IL-1beta), one of the pro-inflammatory cytokines, acts as an endogenous pyrogen and is an important mediator of behavioral and physiological responses to immune stimulation as well as exposure to... -
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- Effects of Plant Water Extract Mixture Ixeris sonchifolia Hance, Oenanthevjavanica, Fagopyrum Esculentum Moench, Hizikia Fusiforme, Zingiber Officinale Roscoe on Mouse Immune Cell Activation Ex vivo
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Ryu HS, Kim JH, Kim HS
- KMID: 2261311
- Korean J Nutr.
- 2008 Mar;41(2):141-146.
Ixeris sonchifolia Hance (Godulbaegi), Oenanthe javanica (Dolminari), Fagopyrum esculentum Moench (Buckwheat), Hizikia fusiforme (Seaweed Fusiforme) and Zingiber officinale Roscoe (Ginger) have been used respectively as one of folk remedies as... -
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- IL-1beta Induces Lysozyme Overexpression through a Mechanism Involving ERK/p38 Mitogen Activated Protein Kinase Activation in Human Airway Epithelial Cells
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Kim YS, Yang WS, Moon UY, Lee JG, Yoon JH
- KMID: 2297667
- J Rhinol.
- 2007 Nov;14(2):100-105.
BACKGROUND AND OBJECTIVES: Lysozyme, a major serous component of airway epithelial secretions, plays an important role in airway defense. However, little is understood about the regulation of its expression and... -
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