- Anti-Inflammatory Effect for Atherosclerosis Progression by Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitor in a Normoglycemic Rabbit Model
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Lee SG, Lee SJ, Lee JJ, Kim JS, Lee OH, Kim CK, Kim D, Lee YH, Oh J, Park S, Jeon OH, Hong SJ, Ahn CM, Kim BK, Ko YG, Choi D, Hong MK, Jang Y
- KMID: 2471785
- Korean Circ J.
- 2020 May;50(5):443-457.
- doi: 10.4070/kcj.2019.0296
BACKGROUND AND OBJECTIVES: We sought to investigate an anti-atherosclerotic and anti-inflammatory effect of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in normoglycemic atherosclerotic rabbit model. METHODS: Male New Zealand white rabbits (n=26) were fed... -
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- A Prospective Observation of Psychological Distress in Patients With Anaphylaxis
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Lee Y, Chang HY, Kim SH, Yang MS, Koh YI, Kang HR, Choi JH, Kim CW, Park HK, Kim JH, Nam YH, Kim TB, Hur GY, Jung JW, Park KH, Kim MA, Kim J, Yoon J, Ye YM
- KMID: 2471232
- Allergy Asthma Immunol Res.
- 2020 May;12(3):496-506.
- doi: 10.4168/aair.2020.12.3.496
PURPOSE: Anaphylaxis is an immediate allergic reaction characterized by potentially life-threatening, severe, systemic manifestations. While studies have evaluated links between serious illness and posttraumatic stress disorder (PTSD), few have investigated... -
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- Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
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Kim HL, Ha AW, Kim WK
- KMID: 2471878
- Nutr Res Pract.
- 2020 Apr;14(2):109-116.
- doi: 10.4162/nrp.2020.14.2.109
BACKGROUND/OBJECTIVES: Excessive intake of simple sugars induces obesity and increases the risk of inflammation. Thus, interest in alternative sweeteners as a sugar substitute is increasing. The purpose of this study... -
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- Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?
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Asan G, Derin ME, DoÄŸan HO, Bayram M, Åžahin M, Åžahin A
- KMID: 2471797
- J Korean Med Sci.
- 2020 Mar;35(10):e63.
- doi: 10.3346/jkms.2020.35.e63
BACKGROUND: Familial Mediterranean fever (FMF) is an autoinflammatory disease that has self-limiting inflammatory attacks during polyserositis. Hepcidin is a protein, and interleukin-6 stimulation increases hepcidin levels. Calprotectin (CLP) is a... -
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- Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats
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Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK
- KMID: 2471038
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):165-171.
- doi: 10.4196/kjpp.2020.24.2.165
Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma... -
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- Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression
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Zhang X, Deng QH, Deng JH, Wang SJ, Chen Q
- KMID: 2471035
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):137-147.
- doi: 10.4196/kjpp.2020.24.2.137
Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis... -
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- MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis
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Liu H, Li S, Jiang W, Li Y
- KMID: 2470910
- Korean Circ J.
- 2020 Mar;50(3):250-263.
- doi: 10.4070/kcj.2019.0107
BACKGROUND AND OBJECTIVES: To reveal the detail mechanism of miR-484 on myocardial ischemia-reperfusion (MI/R) injury. METHODS: Rats model of MI/R injury was established based on control (Con; sham operate) group, ischemia-reperfusion... -
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- Urinary Biomarkers may Complement the Cleveland Score for Prediction of Adverse Kidney Events After Cardiac Surgery: A Pilot Study
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Albert C, Haase M, Albert A, Kropf S, Bellomo R, Westphal S, Westerman , Braun-Dullaeus RC, Haase-Fielitz A
- KMID: 2460910
- Ann Lab Med.
- 2020 Mar;40(2):131-141.
- doi: 10.3343/alm.2020.40.2.131
BACKGROUND: The ability of urinary biomarkers to complement established clinical risk prediction models for postoperative adverse kidney events is unclear. We assessed the effect of urinary biomarkers linked to suspected... -
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- The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix
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Park H, Hong S, Yoo HN, Kim YM, Lee SJ, Park KH
- KMID: 2470777
- J Korean Med Sci.
- 2020 Feb;35(7):e26.
- doi: 10.3346/jkms.2020.35.e26
BACKGROUND: We aimed to investigate whether various immune-related plasma proteins, alone or in combination with conventional clinical risk factors, can predict spontaneous preterm delivery (SPTD) and intra-amniotic infection in women... -
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- 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis
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Kim H, Baek S, Hong SM, Lee J, Jung SM, Lee J, Cho ML, Kwok SK, Park SH
- KMID: 2469943
- J Korean Med Sci.
- 2020 Feb;35(6):e40.
- doi: 10.3346/jkms.2020.35.e40
BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity... -
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- Effect of Diquafosol on Hyperosmotic Stress-induced Tumor Necrosis Factor-α and Interleukin-6 Expression in Human Corneal Epithelial Cells
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Kim YH, Yang IJ, Nguyen LT, Gum SI, Yu S, Lee GJ, Kim BA, Jung JC, Park YJ
- KMID: 2469281
- Korean J Ophthalmol.
- 2020 Feb;34(1):1-10.
- doi: 10.3341/kjo.2019.0046
PURPOSE: Diquafosol is a pharmaceutical drug used for dry eye treatment with a novel mechanism of action. It is a purinergic P2Y2 receptor agonist that promotes the secretion of tears... -
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- A Comparative Study of the Effect of Flaxseed Oil and Sunflower Oil on the Coagulation Score, Selected Oxidative and Inflammatory Parameters in Metabolic Syndrome Patients
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Akrami A, Makiabadi , Askarpour , Zamani K, Hadi A, Mokari-Yamchi A, Babajafari S, Faghih S, Hojhabrimanesh A
- KMID: 2468665
- Clin Nutr Res.
- 2020 Jan;9(1):63-72.
- doi: 10.7762/cnr.2020.9.1.63
Metabolic syndrome (MetS) is a chronic disease with inflammatory and hypercoagulable states. The current study aimed to compare the effects of flaxseed oil and sunflower oil consumption on the coagulation... -
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- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
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Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
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- Effects of 12 Weeks of Combined Exercise on Vascular Function-Related Inflammation Factors, Carotid Intima-Media Thickness and Physical Fitness in Obese 40s-Aged Women with Metabolic Syndrome
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Kim K
- KMID: 2466809
- Korean J Sports Med.
- 2019 Dec;37(4):184-194.
- doi: 10.5763/kjsm.2019.37.4.184
PURPOSE: The purpose of this study was to investigate the effects of 12 weeks of combined exercise on vascular function-related inflammation, carotid intima-media thickness and fitness factors in obese middle-aged... -
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- Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner
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Gim E, Shim DW, Hwang I, Shin OS, Yu JW
- KMID: 2466610
- Immune Netw.
- 2019 Dec;19(6):e40.
- doi: 10.4110/in.2019.19.e40
Zika virus (ZIKV) is a mosquito-borne flavivirus associated with severe neurological disorders including Guillain-Barré syndrome and microcephaly. The host innate immune responses against ZIKV infection are essential for protection; however,... -
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- Examination of protective and therapeutic effects of ruscogenin on cerulein-induced experimental acute pancreatitis in rats
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Ercan G, Ä°lbar Tartar R, Solmaz A, Gulcicek O, Karagulle , Meric S, Cayoren H, Kusaslan R, Kemik A, Gokceoglu Kayali D, Cetinel S, Celik A
- KMID: 2464782
- Ann Surg Treat Res.
- 2019 Dec;97(6):271-281.
- doi: 10.4174/astr.2019.97.6.271
PURPOSE: To determine the potential protective and therapeutic effects and action mechanism of ruscogenin on cerulein-induced acute pancreatitis (AP) model in rats. METHODS: Overall, 32 rats were attenuated to the sham... -
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- Effect of Polydeoxyribonucleotide on Lipopolysaccharide and Sevoflurane-Induced Postoperative Cognitive dysfunction in Human Neuronal SH-SY5Y Cells
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Jeong H, Chung JY, Ko IG, Kim SH, Jin JJ, Hwang L, Moon EJ, Lee BJ, Yi JW
- KMID: 2467317
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S93-S101.
- doi: 10.5213/inj.1938218.109
PURPOSE: Postoperative cognitive dysfunction (POCD) is a complication of surgery characterized by acute cognitive dysfunction, memory impairment, and loss of attention. The effect of polydeoxyribonucleotide (PDRN) on the POCD environment... -
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- Inflammation as the Potential Basis in Depression
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Maeng SH, Hong H
- KMID: 2467314
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S63-S71.
- doi: 10.5213/inj.1938226.113
There is growing evidence of the association between inflammation and stress-related disorders including depression. The positive correlation between the increased levels of inflammatory cytokines observed in patients with other diseases... -
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- Hyaluronic acid has chondroprotective and joint-preserving effects on LPS-induced synovitis in horses
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Neuenschwander HM, Moreira JJ, Vendruscolo CP, Fülber J, Seidel SR, Michelacci YM, Baccarin R
- KMID: 2464083
- J Vet Sci.
- 2019 Nov;20(6):e67.
- doi: 10.4142/jvs.2019.20.e67
The intra-articular use of hyaluronic acid (HA) for the treatment of synovitis and osteoarthritis is still controversial. As a consequence, corticosteroids remain the most frequently employed therapeutic agents, despite their... -
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- Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes
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Bang M, Kim DG, Gonzales E, Kwon KJ, Shin CY
- KMID: 2462880
- Biomol Ther.
- 2019 Nov;27(6):530-539.
- doi: 10.4062/biomolther.2019.151
Brain aging is an inevitable process characterized by structural and functional changes and is a major risk factor for neurodegenerative diseases. Most brain aging studies are focused on neurons and... -
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