- Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp
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Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo JH
- KMID: 2471233
- Allergy Asthma Immunol Res.
- 2020 May;12(3):507-522.
- doi: 10.4168/aair.2020.12.3.507
PURPOSE: Th17-associated inflammation is increased in chronic rhinosinusitis with nasal polyp (CRSwNP), and is associated with disease severity and steroid resistance. Overexpressed interleukin (IL)-17A affects CRSwNP by tissue remodeling, eosinophilic... -
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- Circulating Interleukin-18 Level in Systemic Lupus Erythematosus
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Lee YH, Song GG
- KMID: 2471952
- J Rheum Dis.
- 2020 Apr;27(2):110-115.
- doi: 10.4078/jrd.2020.27.2.110
OBJECTIVE: This study aimed to evaluate the relationship between circulating interleukin (IL)-18 levels and systemic lupus erythematosus (SLE) and establish a correlation between plasma/serum IL-18 levels and SLE activity. METHODS: We... -
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- Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
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Kim HL, Ha AW, Kim WK
- KMID: 2471878
- Nutr Res Pract.
- 2020 Apr;14(2):109-116.
- doi: 10.4162/nrp.2020.14.2.109
BACKGROUND/OBJECTIVES: Excessive intake of simple sugars induces obesity and increases the risk of inflammation. Thus, interest in alternative sweeteners as a sugar substitute is increasing. The purpose of this study... -
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- Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats
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Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK
- KMID: 2471038
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):165-171.
- doi: 10.4196/kjpp.2020.24.2.165
Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma... -
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- MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis
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Liu H, Li S, Jiang W, Li Y
- KMID: 2470910
- Korean Circ J.
- 2020 Mar;50(3):250-263.
- doi: 10.4070/kcj.2019.0107
BACKGROUND AND OBJECTIVES: To reveal the detail mechanism of miR-484 on myocardial ischemia-reperfusion (MI/R) injury. METHODS: Rats model of MI/R injury was established based on control (Con; sham operate) group, ischemia-reperfusion... -
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- Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model
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Khalmuratova R, Lee M, Park JW, Shin HW
- KMID: 2468464
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):306-321.
- doi: 10.4168/aair.2020.12.2.306
PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant... -
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- The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix
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Park H, Hong S, Yoo HN, Kim YM, Lee SJ, Park KH
- KMID: 2470777
- J Korean Med Sci.
- 2020 Feb;35(7):e26.
- doi: 10.3346/jkms.2020.35.e26
BACKGROUND: We aimed to investigate whether various immune-related plasma proteins, alone or in combination with conventional clinical risk factors, can predict spontaneous preterm delivery (SPTD) and intra-amniotic infection in women... -
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- 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis
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Kim H, Baek S, Hong SM, Lee J, Jung SM, Lee J, Cho ML, Kwok SK, Park SH
- KMID: 2469943
- J Korean Med Sci.
- 2020 Feb;35(6):e40.
- doi: 10.3346/jkms.2020.35.e40
BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity... -
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- Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study
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Lim HJ, Han MH, Lee EH, Eun DH, Kim JY, Lee WJ, Lee SJ, Kim DW, Park TI, Kim SH, Jang YH
- KMID: 2467198
- Ann Dermatol.
- 2020 Feb;32(1):31-37.
- doi: 10.5021/ad.2020.32.1.31
BACKGROUND: Based on clinical and genetic differences, atopic dermatitis (AD) and psoriasis have been classified in two different diseases, but recently, some authors regarded them as in one spectrum. The... -
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- MicroRNA-10b Plays a Role in Bone Formation by Suppressing Interleukin-22 in Ankylosing Spondylitis
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Park PR, Jo S, Jin SH, Kim TJ
- KMID: 2471963
- J Rheum Dis.
- 2020 Jan;27(1):61-67.
- doi: 10.4078/jrd.2020.27.1.61
OBJECTIVE: The microRNA (miR)-10b is the T helper (Th) 17 cell specific in patients with ankylosing spondylitis (AS). The interleukin (IL)-22, which is closely related to Th17 cells, has been... -
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- Antibiotics-Induced Dysbiosis of Intestinal Microbiota Aggravates Atopic Dermatitis in Mice by Altered Short-Chain Fatty Acids
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Kim HJ, Lee SH, Hong SJ
- KMID: 2462578
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):137-148.
- doi: 10.4168/aair.2020.12.1.137
PURPOSE: Alterations in the intestinal microbiota in early life affects the development of atopic dermatitis (AD) in humans. This study aimed to further investigate the effects of gut dysbiosis in... -
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- Elastase-Positive Neutrophils Are Associated With Refractoriness of Chronic Rhinosinusitis With Nasal Polyps in an Asian Population
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Kim DK, Kim JY, Han YE, Kim JK, Lim HS, Eun KM, Yang SK, Kim DW
- KMID: 2462571
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):42-55.
- doi: 10.4168/aair.2020.12.1.42
PURPOSE: Various immune cells, including eosinophils and neutrophils, are known to contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the current understanding of the role of... -
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- Baicalein Treatment Promotes Osteoblast Proliferation and Osteogenic Differentiation through Activation of Immediate Early Response 3
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Lee SI
- KMID: 2469741
- J Dent Hyg Sci.
- 2019 Dec;19(4):254-260.
- doi: 10.17135/jdhs.2019.19.4.254
BACKGROUND: The primary aims of periodontal disease treatment is to remove dental plaque and calculus, the main causes of tooth loss, and restore periodontal tissue destroyed by inflammation. Periodontal disease... -
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- Anti-Helicobacter pylori, Anti-apoptotic, and Cytoprotective Effects of Threonine Synthesized from Corynebacterium glutamicum in Gastric Epithelial Cells
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An JM, Kim YS, Hong YG, Hah BS, Sohn MS, Hahm KB
- KMID: 2469316
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Dec;19(4):245-256.
- doi: 10.7704/kjhugr.2019.0011
BACKGROUND/AIMS: Among irritants causing gastric ulcer, Helicobacter pylori (H. pylori) might be pivotal, after which eradication became essential way in either inhibiting ulcerogenesis or preventing ulcer recurrence. Since threonine is... -
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- Evaluation of Anti-inflammatory and Regenerative Efficiency of Naringin and Naringenin in Degenerated Human Nucleus Pulposus Cells: Biological and Molecular Modeling Studies
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Devraj VM, Vemuri SK, Banala RR, Gunda SK, AV GR, GPV S
- KMID: 2467417
- Asian Spine J.
- 2019 Dec;13(6):875-889.
- doi: 10.31616/asj.2019.0073
STUDY DESIGN: Development of an in vitro model for assessing the anti-inflammatory efficacies of naringin (Nar) and naringenin (NG). PURPOSE: To evaluate the efficacy of natural flavonoids as therapeutic drugs against... -
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- Effects of remifentanil preconditioning on factors related to uterine contraction in WISH cells
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Kim CH, Lee SH, Kim EJ, Ahn JH, Choi EJ, Yoon JU, Choi IS
- KMID: 2466649
- J Dent Anesth Pain Med.
- 2019 Dec;19(6):343-351.
- doi: 10.17245/jdapm.2019.19.6.343
BACKGROUND: Preterm labor and miscarriage may occur in stressful situations, such as a surgical operation or infection during pregnancy. Pharyngeal and buccal abscess and facial bone fractures are inevitable dental... -
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- Effect of Polydeoxyribonucleotide on Lipopolysaccharide and Sevoflurane-Induced Postoperative Cognitive dysfunction in Human Neuronal SH-SY5Y Cells
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Jeong H, Chung JY, Ko IG, Kim SH, Jin JJ, Hwang L, Moon EJ, Lee BJ, Yi JW
- KMID: 2467317
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S93-S101.
- doi: 10.5213/inj.1938218.109
PURPOSE: Postoperative cognitive dysfunction (POCD) is a complication of surgery characterized by acute cognitive dysfunction, memory impairment, and loss of attention. The effect of polydeoxyribonucleotide (PDRN) on the POCD environment... -
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- Inflammation as the Potential Basis in Depression
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Maeng SH, Hong H
- KMID: 2467314
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S63-S71.
- doi: 10.5213/inj.1938226.113
There is growing evidence of the association between inflammation and stress-related disorders including depression. The positive correlation between the increased levels of inflammatory cytokines observed in patients with other diseases... -
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- Hyaluronic acid has chondroprotective and joint-preserving effects on LPS-induced synovitis in horses
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Neuenschwander HM, Moreira JJ, Vendruscolo CP, Fülber J, Seidel SR, Michelacci YM, Baccarin R
- KMID: 2464083
- J Vet Sci.
- 2019 Nov;20(6):e67.
- doi: 10.4142/jvs.2019.20.e67
The intra-articular use of hyaluronic acid (HA) for the treatment of synovitis and osteoarthritis is still controversial. As a consequence, corticosteroids remain the most frequently employed therapeutic agents, despite their... -
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- Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice
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Cao W, Mo K, Wei S, Lan X, Zhang W, Jiang W
- KMID: 2461043
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):501-508.
- doi: 10.4196/kjpp.2019.23.6.501
Rosmarinic acid (RA) is a natural polyphenolic compound that exists in many medicinal species of Boraginaceae and Lamiaceae. The previous studies have revealed that RA had therapeutic effects on hepatocellular... -
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