J Korean Diabetes.  2013 Dec;14(4):190-193. 10.4093/jkd.2013.14.4.190.

Diabetes and Vitamin D

• Park JH
• Kim MK

• KMID: 2173934
• DOI: http://doi.org/10.4093/jkd.2013.14.4.190

Abstract

Recent cross-sectional and prospective studies suggest an association between vitamin D deficiency and type 2 diabetes mellitus risk. Vitamin D metabolism may play a role in diabetes mellitus pathogenesis independently of known risk factors. The decrease in vitamin D levels may occur through several mechanisms such as a decrease in the calcium concentration, an increase in parathyroid hormones, or a direct effect of vitamin D on worsening insulin resistance and secretion, thus augmenting the risk of developing type 2 diabetes. However, doubt remains as to whether low vitamin D levels are causal or merely a marker of worse disease or worse health status. Interventional studies have provided conflicting and inconclusive results due to the different populations studies, dose and time frame of vitamin D supplementation. Further studies are required.

Keyword

Vitamin D; Diabetes mellitus; Obesity

MeSH Terms

Calcium
Diabetes Mellitus
Diabetes Mellitus, Type 2
Insulin Resistance
Metabolism
Obesity
Risk Factors
Vitamin D Deficiency
Vitamin D*
Vitamins*
Calcium
Vitamin D
Vitamins

Reference

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