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Occurrence of infections in schoolchildren subsequent to supplementation with vitamin D-calcium or zinc: a randomized, double-blind, placebo-controlled trial

Mandlik R, Mughal Z, Khadilkar , Chiplonkar S, Ekbote V, Kajale N, Patwardhan V, Padidela R, Khadilkar

BACKGROUND/OBJECTIVES: Vitamin D and zinc are recognized for their roles in immune-modulation, and their deficiencies are suggested to be important risk factors for childhood infections. This study, therefore, undertook to...
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Vitamin D and Male Fertility: An Updated Review

Cito G, Cocci A, Micelli E, Gabutti A, Russo GI, Coccia ME, Franco G, Serni S, Carini M, Natali A

To date, the key role of vitamin D in male reproductive system has been suggested, since the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the testis...
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Validity of Diagnostic Codes for Identification of Psoriasis Patients in Korea

Ham SP, Oh JH, Park HJ, Kim JU, Kim HY, Jung SY, Choi SY, Seol JE, Kim H, Kim MS, Lee UH, Choi M, Park HJ

BACKGROUND: Recently, the number of nationwide medical researches on psoriasis using the National Health Insurance Service database has been on the rise. However, identification of psoriasis using diagnostic codes alone...
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Vitamin D Deficiency at Mid-Pregnancy Is Associated with a Higher Risk of Postpartum Glucose Intolerance in Women with Gestational Diabetes Mellitus

Kim KS, Park SW, Cho YW, Kim SK

BACKGROUND: To evaluate the association between serum 25-hydroxyvitamin D (25(OH)D) at mid-pregnancy and postpartum glucose intolerance in women with gestational diabetes mellitus (GDM). METHODS: We enrolled 348 pregnant women diagnosed with...
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Can Current Recommendations on Sun Exposure Sufficiently Increase Serum Vitamin D Level?: One-Month Randomized Clinical Trial

Lee YM, Kim SA, Lee DH

BACKGROUND: Lack of sunlight exposure is the primary reason for the worldwide epidemic of vitamin D deficiency. Although recommended sunlight exposure guidelines exist, there is no evidence regarding whether current...
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Status of health and nutritional intake of the elderly in long-term care facilities: focus on Gwangju Metropolitan City

Han G, Yang E

PURPOSE: This study assessed the food intake and nutritional status of the elderly in long-term care facilities in order to provide adequate food services and improve the nutritional status. METHODS: The...
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1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis

Kim H, Baek S, Hong SM, Lee J, Jung SM, Lee J, Cho ML, Kwok SK, Park SH

BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity...
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The association of potassium intake with bone mineral density and the prevalence of osteoporosis among older Korean adults

Ha J, Kim SA, Lim K, Shin S

BACKGROUND/OBJECTIVES: Osteoporosis is characterized by low bone mass and results in vulnerability to fracture. Calcium and vitamin D are known to play an important role in bone health. Recently, potassium...
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Development of the anti-cancer food scoring system 2.0: Validation and nutritional analyses of quantitative anti-cancer food scoring model

Hong YJ, Kim J, Lee HY, Rim CH

BACKGROUND/OBJECTIVES: We have previously designed the anti-cancer food scoring model (ACFS) 1.0, an evidence-based quantitative tool analyzing the anti-cancer or carcinogenic potential of diets. Analysis was performed using simple quantitative...
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Association of vitamin D deficiency with clinical outcomes in critically ill Korean children

Jhang WK, Kim DH, Park SJ

BACKGROUND/OBJECTIVES: Vitamin D is a pleiotropic hormone that affects various body organ systems. We evaluated the prevalence of a vitamin D deficiency (VDD) and its potential role in the clinical...
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An Empirical Study on the Effect of Short-Term Regular Vitamin D3 Supplement Therapy on Blood Pressure and Exercise Tolerance in Heart Failure Patients

Hosseinzadeh F, Oskouei NJ, Ghavamzadeh S

The receptor of vitamin D is expressed in almost all body cells, including vascular endothelial cells and cardiomyocytes. Vitamin D deficiency has been observed widespread amongst heart failure (HF) patients,...
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Nationwide Cross-sectional Study of Association between Pterygium and Alkaline Phosphatase in a Population from Korea

Kim HJ, Rah SH, Kim SW, Kim SH

PURPOSE: We determined whether elevated serum alkaline phosphatase (ALP) was related to prevalence, location, type, length, and recurrence of pterygium in a population from the Republic of Korea. METHODS: A nationwide...
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Effect of Vitamin D on Bone Mineral Density Changes in Patients with Breast Cancer Receiving Adjuvant Aromatase Inhibitor Therapy

Park SH, Kim EY, Park CH

PURPOSE: We assessed bone mineral density (BMD) changes with aromatase inhibitor (AI) treatment in women with breast cancer and determined whether BMD T-scores changed with vitamin D supplementation. METHODS: This single-center,...
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Serum 25-hydroxyvitamin D concentrations in Japanese postmenopausal women with osteoporotic fractures

Yamanaka Y, Menuki K, Zenke Y, Ikeda S, Hatakeyama E, Kawano K, Nishida S, Tanaka H, Yumisashi , Sakai A

OBJECTIVES: To assess the vitamin D status in postmenopausal women with osteoporotic fractures, determine its concentration by fracture site at the clinical setting, and compare the proportion of vitamin D...
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Association between High-Density Lipoprotein Cholesterol and Vitamin D Levels in Adult Men in the Fifth Korea National Health and Nutrition Examination Survey

Jung IK

BACKGROUND: Patients with metabolic syndrome had low high-density lipoprotein cholesterol (HDL-C) levels. Moreover, vitamin D deficiency is also related to metabolic syndrome. This study aimed to investigate the association between...
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Skeletal mineralization: mechanisms and diseases

Michigami

Skeletal mineralization is initiated in matrix vesicles (MVs), the small extracellular vesicles derived from osteoblasts and chondrocytes. Calcium and inorganic phosphate (Pi) taken up by MVs form hydroxyapatite crystals, which...
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Biomarkers in Drug Free Subjects with Depression : Correlation with Tryptophan

Samad N, Yasmin F, Manzoor N

OBJECTIVE: Depression is a prevalent condition that is costly to individuals and society. In view of a role of tryptophan (TRP), selenium (Se), vitamin D (Vit D), magnesium (Mg) and...
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Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review

Riazi H, Ghazanfarpour M, Taebi M, Abdolahian S

Menopause is associated with the onset of climacteric symptoms due to low estradiol levels, which may cause insufficient maturation of the vaginal mucosa. Vitamin D may regulate the growth and...
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Association between vitamin D deficiency and anemia among Korean adolescent girls and young women

Jang H, Park S, Park K

PURPOSE: Although vitamin D deficiency is common among Korean adolescent girls and young women, few studies have explored the potential health effects of vitamin D deficiency in this vulnerable population....
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Association of circulating 25-hydroxyvitamin D levels with hypertension and blood pressure values in Korean adults: A Mendelian randomization study on a subset of the Korea National Health and Nutrition Survey 2011–2012 population

Kwak SY, Cho Y, Oh H, Shin MJ

BACKGROUND/OBJECTIVES: Lower circulating 25-hydroxyvitamin D [25(OH)D] levels are associated with a higher risk of hypertension (HTN); however, it remains unclear whether the relationship is causal. We aimed to evaluate the...
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