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High prevalence of hypovitaminosis D3 among pregnant women in central Iran: correlation with newborn vitamin D3 levels and negative association with gestational age

Dorreh F, Ahmadi R, Absalan A, Akhondzadeh A, Najdi N, Ghaffari K

Objective Hypovitaminosis D3 is a significant concern among pregnant women and their newborns because vitamin D3 (Vit-D3) plays a crucial role in embryonic growth, development, and health. This study aimed...
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Advances in the Administration of Vitamin D Analogues to Support Bone Health and Treat Chronic Diseases

Kanemoto Y, Iwaki M, Sawada T, Nojiri K, Kurokawa T, Tsutsumi R, Nagasawa K, Kato S

Vitamin D (VD) exerts a wide variety of biological actions in addition to its well-known roles in calcium homeostasis. Nutritional VD deficiency induces rachitic abnormalities in growing children and osteomalacia...
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Calcium, Vitamin D, and Colorectal Cancer

Wi YJ, Na SY

Colorectal cancer has a high incidence and mortality worldwide, with Westernized lifestyles and diet being significant contributing factors. Vitamin D and calcium have been known to reduce the incidence of...
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Circulating Vitamin D Level and Risk of Sudden Cardiac Death and Cardiovascular Mortality: A Dose-Response Meta-Analysis of Prospective Studies

Kong SY, Jung E, Hwang Ss, Ro YS, Shin SD, Cha Kc, Hwang SO

Background: We conducted a comprehensive meta-analysis of prospective cohort studies to analyze the effect of circulating vitamin D level on the risk of sudden cardiac death (SCD) and cardiovascular disease...
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Trends of vitamin D in asthma in the pediatric population for two decades: a systematic review

Sung M

Vitamin D exhibits anti-inflammatory properties through multiple mechanisms. Vitamin D deficiency is associated with increased inflammation, exacerbations, and overall worse outcomes in pediatric asthma and is observed in asthmatic children...
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Vitamin D Levels and Risk of Male Factor Infertility: A Mendelian Randomization Study

Yuan C, Xiang L, Jian Z, Liao B

Purpose No consensus exists about the causal relationship between vitamin D (VD) and male factor infertility due to heterogeneity and confounding factors even in randomized controlled trials (RCTs). This study aimed...
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Estimated dietary vitamin D intake and major vitamin D food sources of Koreans: based on the Korea National Health and Nutrition Examination Survey 2016–2019

Kim KN, Lee JS, Shim JS, Yoon MO, Lee HS

BACKGROUND/OBJECTIVES: The purpose of this study was to establish a database (DB) of foods containing vitamin D that were investigated in the Korea National Health and Nutrition Examination Survey (KNHANES),...
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Effects of Bazedoxifene/Vitamin D Combination Therapy on Serum Vitamin D Levels and Bone Turnover Markers in Postmenopausal Women with Osteopenia: A Randomized Controlled Trial

Jeong C, Ha J, Yoo JI, Lee YK, Kim JH, Ha YC, Min YK, Byun DW, Baek KH, Chung HY

Background: This study aimed to evaluate the effectiveness of bazedoxifene/vitamin D combination therapy in preventing osteoporosis in postmenopausal women with osteopenia. Methods: This was an open-label, multicenter randomized-controlled, phase 4 clinical...
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Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis

Zhang M, Wu Y, Lu Z, Song M, Huang X, Mi L, Yang J, Cui X

The effect of vitamin D supplementation on individuals with autism spectrum disorder (ASD) is inconclusive. We aimed to conduct a meta-analysis of the available randomized controlled trials (RCTs) to explore...
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Effect of vitamin D vaginal suppository on sexual functioning among postmenopausal women: A three-arm randomized controlled clinical trial

Sarebani Z, Chegini V, Chen H, Aali E, Mirzadeh M, Abbaspour M, Griffiths MD, Alimoradi Z

Objective Vaginal atrophy, the second most common complication of menopause, can lead to sexual dysfunction. This study evaluated the effect of a vitamin D vaginal suppository on sexual functioning in...
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New Insights into Calorie Restriction Induced Bone Loss

Liu L, Rosen CJ

Caloric restriction (CR) is now a popular lifestyle choice due to its ability in experimental animals to improve lifespan, reduce body weight, and lessen oxidative stress. However, more and more...
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Is There a Relevant Clinical Impact in Differentiating Idiopathic versus Unexplained Male Infertility?

Corsini C, Boeri L, Candela L, Pozzi E, Belladelli F, Capogrosso P, Fallara G, Schifano N, Cignoli D, Ventimiglia E, D’Arma A, Alfano M, Montorsi F, Salonia A

Purpose Overall, male factor infertility (MFI) accounts for up to 50% of etiologies of couple’s infertility, with almost 30% of MFI cases being idiopathic in nature. Idiopathic MFI does not support...
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Exploring optimal supplementation for people with vitamin D deficiency

Choi HS

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The Difference between Serum Vitamin D Level and Depressive Symptoms in Korean Adult Women before and after Menopause: The 5th (2010–2012) Korean National Health and Nutrition Examination Survey

Lee S, Choi HW, Bae WK, Shin EY

Background: The relationship between serum vitamin D levels and depressive symptoms has not been consistent in previous studies in Korean women. Menopause is known to be related to depression and...
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Association of serum 25-hydroxyvitamin D concentrations with Schirmer tear test 1 and tear film breakup time in dogs

Kim Y, Kang S, Seo K

Background: The association between vitamin D and canine keratoconjunctivitis sicca (KCS) has not been investigated in dogs. Objectives: To investigate the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with Schirmer tear...
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The Effects of Resveratrol on Silica-Induced Lung Oxidative Stress and Inflammation in Rat

Esfahani M, Rahbar AH, Asl SS, Bashirian S, Moeini ESM, Mehri F

Background Chronic exposure to silica is related with the provocation of an inflammatory response and oxidative stress mechanism. Vitamin D has multiple benefits in biological activities particularly respiratory system disease. Method In this...
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Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence

Octavius GS, Shakila A, Meliani M, Halim A

Purpose: This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents. Methods: This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random...
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Effect of cinacalcet-mediated parathyroid hormone reduction on vitamin D metabolism in high-fat dietinduced obese mice

Kim TY, Park CY, Han SN

Purpose: Obesity is associated with alterations in vitamin D metabolism and elevation of parathyroid hormone (PTH). Increased PTH level in obesity is likely one of the factors contributing to the...
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Cardiovascular Impact of Calcium and Vitamin D Supplements: A Narrative Review

Zarzour F, Didi A, Almohaya M, Kendler D

Calcium and vitamin D play an important role in mineral homeostasis and the maintenance of skeletal health. Calcium and vitamin D supplements have been widely used for fracture prevention in...
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Effect of Vitamin D on YKL-40: Rat Hypercholesterolemia Model

Kocabas R

Background and Objectives: YKL-40 is considered to be associated with cardiovascular disease (CVD). In this study, the effect of serum 25(OH) vitamin D [25(OH)VitD] differences between groups on YKL-40 was...
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