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A Case of Idiopathic Hypereosinophilic Syndrome Presenting With Acute Respiratory Distress Syndrome

Lim KS, Ko J, Lee SS, Shin B, Choi DC, Lee BJ

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):98-101.
  • doi: 10.4168/aair.2014.6.1.98
Although idiopathic hypereosinophilic syndrome(IHES) commonly involves the lung, it is rarely associated with acute respiratory distress syndrome (ARDS). Here we describe a case of IHES presented in conjunction with ARDS....
A Case of Codeine Induced Anaphylaxis via Oral Route

Yoo HS, Yang EM, Kim MA, Hwang SH, Shin YS, Ye YM, Nahm DH, Park HS

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):95-97.
  • doi: 10.4168/aair.2014.6.1.95
Codeine is widely prescribed in clinical settings for the relief of pain and non-productive coughs. Common adverse drug reactions to codeine include constipation, euphoria, nausea, and drowsiness. However, there have...
Autologous Immunoglobulin Therapy in Patients With Severe Recalcitrant Atopic Dermatitis: A Preliminary Report

Nahm DH, Cho SM, Kim ME, Kim YJ, Jeon SY

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):89-94.
  • doi: 10.4168/aair.2014.6.1.89
The management of severe recalcitrant atopic dermatitis (AD) is a challenging issue for clinicians and patients. We hypothesized that repeated intramuscular injections of autologous immunoglobulin (autologous immunoglobulin therapy: AIGT) might...
A Novel Synthetic Mycolic Acid Inhibits Bronchial Hyperresponsiveness and Allergic Inflammation in a Mouse Model of Asthma

Kim YJ, Kim HJ, Jeong SK, Lee SH, Kang MJ, Yu HS, Jung YH, Seo JH, Kim BJ, Yu J, Park SJ, Lee YC, Hong SJ

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):83-88.
  • doi: 10.4168/aair.2014.6.1.83
PURPOSE: Recognition of microbes is important to trigger the innate immune system. Mycolic acid (MA) is a component of the cell walls of mycobacteria such as Mycobacterium bovis Bacillus Calmette-Guerin....
A Quantitative Study of Airway Changes on Micro-CT in a Mouse Asthma Model: Comparison With Histopathological Findings

Paik SH, Kim WK, Park JS, Park CS, Jin GY

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):75-82.
  • doi: 10.4168/aair.2014.6.1.75
PURPOSE: To evaluate airway changes in ovalbumin-induced asthmatic mice in terms of postmortem micro-CT images and pathological findings. METHODS: Asthma was induced in mice by intraperitoneal injection and nasal instillation of...
Stimulated Bronchial Epithelial Cells Release Bioactive Lysophosphatidylcholine 16:0, 18:0, and 18:1

Zhuge Y, Yuan Y, van Breemen R, DeGrand M, Holian O, Yoder M, Lum H

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):66-74.
  • doi: 10.4168/aair.2014.6.1.66
PURPOSE: In human subjects and animal models with acute and chronic lung injury, the bioactive lysophosphatidylcholine (LPC) is elevated in lung lining fluids. The increased LPC can promote an inflammatory...
Bioactive Lysophosphatidylcholine 16:0 and 18:0 Are Elevated in Lungs of Asthmatic Subjects

Yoder M, Zhuge Y, Yuan Y, Holian O, Kuo S, van Breemen R, Thomas LL, Lum H

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):61-65.
  • doi: 10.4168/aair.2014.6.1.61
PURPOSE: Asthma is a chronic inflammatory disease of the airways, and is associated with upregulation of phospholipase A2 (PLA2), the enzyme that hydrolyzes phosphatidylcholine, producing lysophosphatidylcholine (LPC) and free fatty...
Gene-Gene Interaction Between CCR3 and Eotaxin Genes: The Relationship With Blood Eosinophilia in Asthma

Lee JH, Jang AS, Park SW, Kim DJ, Park CS

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):55-60.
  • doi: 10.4168/aair.2014.6.1.55
PURPOSE: Eosinophils function as an effector cell in the development of asthma and allergic disease. Eotaxins are cytokines that promote pulmonary eosinophilia via the receptor CCR3. Single-nucleotide polymorphisms (SNPs) in...
Variability of Offending Allergens of Allergic Rhinitis According to Age: Optimization of Skin Prick Test Allergens

Lee JE, Ahn JC, Han DH, Kim DY, Kim JW, Cho SH, Park HW, Rhee CS

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):47-54.
  • doi: 10.4168/aair.2014.6.1.47
PURPOSE: This study evaluates offending allergens in patients with allergic rhinitis (AR) according to age that establish a minimal panel for skin prick test (SPT) allergens required to identify if...
Eosinophilic Airway Inflammation and Airway Hyperresponsiveness According to Aeroallergen Sensitization Pattern in Patients With Lower Airway Symptoms

Jo EJ, Kim MY, Lee SE, Lee SY, Kim MH, Song WJ, Kim SH, Kang HR, Chang YS, Cho SH, Min KU

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):39-46.
  • doi: 10.4168/aair.2014.6.1.39
PURPOSE: Sensitization to specific allergens may be important in the development of allergic airway inflammation and airway hyperresponsiveness (AHR). We evaluated the effect of specific aeroallergen sensitization on eosinophilic airway...
Can Fecal Calprotectin Level Be Used as a Markers of Inflammation in the Diagnosis and Follow-Up of Cow's Milk Protein Allergy?

Beser OF, Sancak S, Erkan T, Kutlu T, Cokugras H, Cokugras F

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):33-38.
  • doi: 10.4168/aair.2014.6.1.33
PURPOSE: Calprotectin is a cytosolic protein with immunomodulatory, antimicrobial, and antiproliferative actions. The concentration of calprotectin increases in infection, inflammation, and malignancy. We determined if calprotectin can be used as...
Fractional Exhaled Nitric Oxide and Impulse Oscillometry in Children With Allergic Rhinitis

Kim YH, Park HB, Kim MJ, Kim HS, Lee HS, Han YK, Kim KW, Sohn MH, Kim KE

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):27-32.
  • doi: 10.4168/aair.2014.6.1.27
PURPOSE: Airway inflammation, bronchial hyper-responsiveness (BHR), and bronchodilator response (BDR) are representative characteristics of asthma. Because allergic rhinitis (AR) is a risk factor for asthma development, we evaluated these 3...
Effects of Methylprednisolone Pulse Therapy on Refractory Mycoplasma pneumoniae Pneumonia in Children

You SY, Jwa HJ, Yang EA, Kil HR, Lee JH

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):22-26.
  • doi: 10.4168/aair.2014.6.1.22
PURPOSE: Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe...
Molecular Genetic Mechanisms of Chronic Urticaria

Losol P, Yoo HS, Park HS

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):13-21.
  • doi: 10.4168/aair.2014.6.1.13
Chronic urticaria (CU) is a common allergic skin disease that requires long-term pharmacological treatment. Some patients with severe CU suffer a poor quality of life. Although the pathogenic mechanisms of...
Histamine-Releasing Factor and Immunoglobulins in Asthma and Allergy

Kawakami T, Kashiwakura JI, Kawakami Y

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):6-12.
  • doi: 10.4168/aair.2014.6.1.6
Factors that can induce the release of histamine from basophils have been studied for more than 30 years. A protein termed histamine-releasing factor (HRF) was purified and molecularly cloned in...
The Efficacy of Glucocorticoid on Macrolide Resistant Mycoplasma Pneumonia in Children

Oh JW

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):3-5.
  • doi: 10.4168/aair.2014.6.1.3
No abstract available.
Embarking on a New Journey With the Allergy, Asthma & Immunology Research

Park HS

  • Allergy Asthma Immunol Res.
  • 2014 Jan;6(1):1-2.
  • doi: 10.4168/aair.2014.6.1.1
No abstract available.

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