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Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level

Kim DY, Jung CS

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):219-224.
  • doi: 10.4196/kjpp.2012.16.3.219
Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave,...
Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

Jin Y, Kim J, Kwak J

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):211-217.
  • doi: 10.4196/kjpp.2012.16.3.211
Recent studies have demonstrated that nitric oxide (NO) activates transient receptor potential vanilloid subtype 1 (TRPV1) via S-nitrosylation of the channel protein. NO also modulates various cellular functions via activation...
Development of Estimation Methods of Skin Oxidation and Evaluation of Anti-Oxidative Effects of Genistein in Topical Formulations

Kim SY, Na YJ, Kim D, Kim Y, Kim HM, Hwang SH, Kwak J, Kuh HJ, Lee J

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):205-209.
  • doi: 10.4196/kjpp.2012.16.3.205
The objective of the present study was to establish the method of measurement of hydrogen peroxide and to estimate the anti-oxidative effect of genistein in the skin. UVB induced skin...
Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells

Lee SK, Lee JY, Joo HK, Cho EJ, Kim CS, Lee SD, Park JB, Jeon BH

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):199-204.
  • doi: 10.4196/kjpp.2012.16.3.199
We evaluated the role of Tat-mediated p66shc transduction on the activation of endothelial nitric oxide synthase in cultured mouse endothelial cells. To construct the Tat-p66shc fusion protein, human full length...
Proteomic Analysis of Colonic Mucosal Tissue from Tuberculous and Ulcerative Colitis Patients

Kwon SC, Won KJ, Jung SH, Lee KP, Lee DY, Park ES, Kim B, Cheon GJ, Han KH

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):193-198.
  • doi: 10.4196/kjpp.2012.16.3.193
Changes in the expression profiles of specific proteins leads to serious human diseases, including colitis. The proteomic changes related to colitis and the differential expression between tuberculous (TC) and ulcerative...
Hop Extract Produces Antinociception by Acting on Opioid System in Mice

Park SH, Sim YB, Kang YJ, Kim SS, Kim CH, Kim SJ, Seo JY, Lim SM, Suh HW

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):187-192.
  • doi: 10.4196/kjpp.2012.16.3.187
In the present study, the antinociceptive profiles of hop extract were characterized in ICR mice. Hop extract administered orally (from 25 to 100 mg/kg) showed an antinociceptive effect in a...
Reduction of Food Intake by Fenofibrate is Associated with Cholecystokinin Release in Long-Evans Tokushima Rats

Park MK, Han Y, Kim MS, Seo E, Kang S, Park SY, Koh H, Kim DK, Lee HJ

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):181-186.
  • doi: 10.4196/kjpp.2012.16.3.181
Fenofibrate is a selective peroxisome proliferator-activated receptor alpha (PPARalpha) activator and is prescribed to treat hyperlipidemia. The mechanism through which PPARalpha agonists reduce food intake, body weight, and adiposity remains...
Yoga Training Improves Metabolic Parameters in Obese Boys

Seo DY, Lee S, Figueroa A, Kim HK, Baek YH, Kwak YS, Kim N, Choi TH, Rhee BD, Ko KS, Park BJ, Park SY, Han J

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):175-180.
  • doi: 10.4196/kjpp.2012.16.3.175
Yoga has been known to have stimulatory or inhibitory effects on the metabolic parameters and to be uncomplicated therapy for obesity. The purpose of the present study was to test...
Generation of CD2+CD8+ NK Cells from c-kit+ Bone Marrow Cells in Porcine

Lim KH, Han JH, Roh YS, Kim B, Kwon JK, You MJ, Han HJ, Ejaz S, Kang CW, Kim JH

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):167-174.
  • doi: 10.4196/kjpp.2012.16.3.167
Natural killer (NK) cells provide one of the initial barriers of cellular host defense against pathogens, in particular intracellular pathogens. Because bone marrow-derived hematopoietic stem cells (HSCs), lymphoid protenitors, can...
Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines

Jang I, Jeon BT, Jeong EA, Kim EJ, Kang D, Lee JS, Jeong BG, Kim JH, Choi BH, Lee JE, Kim JW, Choi JY, Roh GS

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):159-165.
  • doi: 10.4196/kjpp.2012.16.3.159
Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the major histological types of non-small cell lung carcinoma (NSCLC). Although both SCCs and ACs have been characterized histologically and clinically, the...
Ethanol Elicits Inhibitory Effect on the Growth and Proliferation of Tongue Carcinoma Cells by Inducing Cell Cycle Arrest

Le TD, Do TA, Yu R, Yoo H

  • Korean J Physiol Pharmacol.
  • 2012 Jun;16(3):153-158.
  • doi: 10.4196/kjpp.2012.16.3.153
Cellular effects of ethanol in YD-15 tongue carcinoma cells were assessed by MTT assay, caspase activity assay, Western blotting and flow cytometry. Ethanol inhibited the growth and proliferation of YD-15...

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