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Precursor B-Cell Acute Lymphoblastic Leukemia in Two Patients with a History of Cytotoxic Therapy

Shin SP, Song SH, Ko EJ, Kim JS, Park CY, Oh D, Chong SY

  • KMID: 2267836
  • Korean J Med.
  • 2013 Jul;85(1):96-100.
Therapy-related myeloid neoplasms have been well characterized. However, precursor B-cell acute lymphoblastic leukemia in patients with prior malignancies is uncommon, and the effect of prior cytotoxic therapy on development of...
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A Case of Precursor B-cell Lymphoblastic Lymphoma Misdiagnosed as Rosacea

Han EC, Kim DY, Chung JY, Chung HJ, Chung KY

  • KMID: 2302119
  • Korean J Dermatol.
  • 2008 Feb;46(2):264-267.
Precursor B-cell lymphoblastic lymphoma is a rare type of non-Hodgkin's lymphoma seen exclusively in children and young adults. The neoplasm is rare in old age. We report a case of...
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A Case of Secondary Precursor B-cell Acute Lymphoblastic Leukemia Occurring after Treatment of Hemophagocytic Lymphohistiocytosis

Yang SI, Jeon IS

  • KMID: 1448325
  • Clin Pediatr Hematol Oncol.
  • 2011 Oct;18(2):140-143.
Hemophagocytic lymphohistiocytosis (HLH), although uncommon, is illustrated as a dramatic clinical presentation of multi-systemic inflammation due to the impaired activity of cytotoxic T-cell and NK cell. Etoposide, an important component...
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A Case of Pneumatosis Intestinalis in Refractory Acute Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Bae SH, Hwang JY, Kim DK, Kim MS, Kwon HJ, Han JY, Kim SH

  • KMID: 2258986
  • Korean J Med.
  • 2011 Apr;80(4):482-485.
Pneumatosis intestinalis (PI) is an imaging phenomenon that represents air in the bowel wall. The cause of PI is variable, although specific etiologic factors remain unknown. It is an infrequent...
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A Case of Non-T,Non-B Primary Cutaneous Lymphoblastic Lymphoma

Kim JW, Nam SH, Kim KJ, Kim CM, Lee CJ

We herein present a case of a 2-year-old girl with non-Hodgkin's lymphoma(NHL) of the lymphoblastic type involving cutaneous sites at the time of diagnosis. The histological finding was typical of...
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A Case of Pediatric Acute Lymphoblastic Leukemia with Trisomy 5 as a Sole Chromosomal Anomaly: A Prognostic Significance

Cho YH, Jeon IS

We present a case of Korean pediatric patient with pre-B cell type acute lymphoblastic leukemia (ALL) with trisomy 5 as a sole cytogenetic anomaly. Here, we compare and describe the...
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Characterization of clonal immunoglobulin heavy (IGH) V-D-J gene rearrangements and the complementarity-determining region in South Indian patients with precursor B-cell acute lymphoblastic leukemia

Sudhakar N, Rajkumar T, Rajalekshmy KR, Nancy NK

BACKGROUND: This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identified age-related predominance in VDJ rearrangements. METHODS:...
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A Case of Pediatric Precursor B-cell Acute Lymphoblastic Leukemia Associated with Translocations (14;18)(q32;q21) and (8;9)(q24;p13)

Kim HJ, Kim H, Koh KN, Im HJ, Seo JJ, Seo EJ, Park CJ

Precursor B-cell acute lymphoblastic leukemia (ALL), which is the most common subtype of pediatric acute leukemia, generally has a good prognosis. However, the prognosis also depends on the genetic abnormalities...
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Primary cutaneous B-cell lymphoblastic lymphoma in an elderly man

Cho SY, Lee SS, Back DH, Lim KA, Lee YR, Kang HJ

Precursor B-cell lymphoblastic lymphoma (B-LBL) is an uncommon high-grade neoplasm of immature B cells. It occurs predominantly in childhood with extranodal involvement such as skin and bone. Therefore, primary cutaneous...
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Identification of Gene Expression Signatures in Korean Acute Leukemia Patients

Lee KH, Park SW, Kim I, Yoon SS, Park S, Kim BK

  • KMID: 1512143
  • Genomics Inform.
  • 2006 Sep;4(3):97-102.
BACKGROUND: In acute leukemia patients, several successful methods of expression profiling have been used for various purposes, i.e., to identify new disease class, to select a therapeutic target, or to...
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Complete Hematologic Response and Cytogenetic Remission after Imatinib and Dexamethasone Treatment of a Ph+ Precursor B-cell Acute Lymphoblastic Leukemia in Renal Transplantation Patient

Baek SK, Cho KS, Yang BH, Kim SY, Yoon HJ, Jeong K, Ihm CG

In this report, we present a case of a patient with Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia after renal transplantation. The patient, a 65-year-old man, had received a kidney...
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A Case of Acute Lymphoblastic Leukemia with ider(9)(q10)t(9;22)(q34;q11.2)

Huh J, Chung W

ider(9)(q10)t(9;22)(q34;q11.2) is an isochromosome for the long arm of a derivative chromosome 9 generated by a t(9;22), resulting from the deletion of the short arm of chromosome 9. It is...
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ider (9) (q10)t (9;22) (q34;q11.2) as Secondary Karyotypic Aberration of Chronic Myelogeous Leukemia

Choi GJ, Jeon DS, Chun HJ, Kim JR, Song HS, Lee JW

  • KMID: 2225864
  • Korean J Clin Pathol.
  • 1999 Apr;19(2):266-270.
Although occasional patients with chronic myeloid leukemia (CML) have chromosomal changes other than Philadelphia chromosome early in the disease, in typical cases the 9;22 translocation remains the sole abnormality throughout...
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Graft-Versus-Host Disease of the Lung after Allogeneic Hematopoietic Stem Cell Transplantation: A Report of Two Cases

Roh JH, Han J, Yoo KH, Ahn KM, Kim J

  • KMID: 2459601
  • Korean J Pathol.
  • 2009 Aug;43(4):378-381.
Herein, we describe cases of pulmonary acute graft-versus-host disease (aGVHD) in two patients occurring after allogeneic hematopoietic stem cell transplantation (HSCT) due to precursor B-cell acute lymphoblastic leukemia in a...
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Extramedullary B Lymphoblastic Crisis of CML, Presenting as a Leptomeningeal Tumor: A Case Report

Jeong H, Shin B, Bae SY, Lee S, Ryu Y, Kim H, Kim I

We report here on a rare case of a patient who presented with an extramedullary B lymphoblastic crisis as an initial manifestation of chronic myelogenous leukemia (CML). A 71-year-old man...
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Preleukemic State Preceding Acute Lymphocytic Leukemia in Childhood

Sung IH, Park KY, Goo SI, Son BH, Lee SY

  • KMID: 1979980
  • Korean J Pediatr Hematol Oncol.
  • 1997 Oct;4(2):376-382.
OBJECT: Pre-ALL is a very rare preteukemic state, which percedes acute lymphocytic leukemia, while MDS(pre-ANLL), usually the well-known type of preleukemic state, precedes acute non-lymphocytic leukemia. Initially it shows transient...
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Swiprosin-1 Expression Is Up-Regulated through Protein Kinase C-theta and NF-kappaB Pathway in T Cells

Kim YD, Kwon MS, Na BR, Kim HR, Lee HS, Jun CD

Swiprosin-1 exhibits the highest expression in CD8+ T cells and immature B cells and has been proposed to play a role in lymphocyte biology through actin remodeling. However, regulation of...
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Isolated Central Nervous System Relapse of Acute Lymphoblastic Leukemia

Sung SH, Jang IS

Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer and may exhibit central nervous system (CNS) involvement. Advances in chemotherapy and effective CNS prophylaxis have significantly decreased...
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Promoter methylation and expression levels of selected hematopoietic genes in pediatric B-cell acute lymphoblastic leukemia

Musialik E, Bujko M, Kober P, Wypych A, Gawle-Krawczyk K, Matysiak M, Siedlecki

BACKGROUND: Precursor B-cell acute lymphoblastic leukemia (B-cell ALL) is the most common neoplasm in children and is characterized by genetic and epigenetic aberrations in hematopoietic transcription factor (TF) genes. This...
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Identification of a Novel Mutation of Bruton's Tyrosine Kinase(BTK)Gene in a X-linked Agammaglobulinemia(XLA) Family

Baek YJ, Lee JH, Kim JS, Song CH, Park JK, Kim HJ, Jo EK

  • KMID: 2104501
  • J Korean Pediatr Soc.
  • 2000 Dec;43(12):1599-1607.
X-linked agammaglobulinemia(XLA) is a heritable humoral immunodeficiency disease characterized by inefficient expansion of pre-B cells into later B cell stages or incomplete differentiation of B cell precursors to pre-B cells....
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