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Thymol Rich Thymbra capitata Essential Oil Inhibits Quorum Sensing, Virulence and Biofilm Formation of Beta Lactamase Producing Pseudomonas aeruginosa

Qaralleh H

  • Nat Prod Sci.
  • 2019 Jun;25(2):172-180.
  • doi: 10.20307/nps.2019.25.2.172
Infections with Pseudomonas aeruginosa are difficult to treat not only because it is often associated with multidrug-resistant infections but also it is able to form biofilm. The aim of this...
Identification of a Novel Function of Extract of Gingko biloba (EGb 761®) as a Regulator of PYY Secretion and FFA4 Activation

Kim HY, Kim K

  • Nat Prod Sci.
  • 2019 Jun;25(2):165-171.
  • doi: 10.20307/nps.2019.25.2.165
Although the functions of a standardized extract of Gingko biloba leaves (EGb 761®) has been reported with regard to neurobiological properties, no attention has been paid to the impact of...
Evaluation of Acute and Sub-acute Oral Toxicity Effect of Aquilaria malaccensis Leaves Aqueous Extract in Male ICR Mice

Musa NH, Zain HH, Ibrahim H, Jamil NN

  • Nat Prod Sci.
  • 2019 Jun;25(2):157-164.
  • doi: 10.20307/nps.2019.25.2.157
The study was conducted to investigate the acute and sub-acute toxicity effect of Aquilaria malaccensis leaves aqueous extract (AEAM) towards male ICR mice in terms of body weight, relative organ...
Simultaneous Extraction and Separation of Oil and Azadirachtin from Seeds and Leaves of Azadirachta indica using Binary Solvent Extraction

Subramanian S, Salleh AS, Bachmann R, Hossain MS

  • Nat Prod Sci.
  • 2019 Jun;25(2):150-156.
  • doi: 10.20307/nps.2019.25.2.150
Conventional extraction of oil and azadirachtin, a botanical insecticide, from Azadirachta indica involves defatting the seeds and leaves using hexane followed by azadirachtin extraction with a polar solvent. In order...
Enhanced Antioxidant and Anticancer Properties of Processed Eucommiae Cortex

Yoon HJ, Park SH, Lee HJ

  • Nat Prod Sci.
  • 2019 Jun;25(2):143-149.
  • doi: 10.20307/nps.2019.25.2.143
Eucommiae Cortex (EC), bark of Eucommia ulmoides, has been known as a traditional medicine to regulate hypertension and immune system. Because silk of gum in the EC blocks the release...
Dendropanax morbifera Extract Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Inhibition of Reactive Oxygen Species Generation and Calcium Perturbation

Lim L, Ju S, Song H

  • Nat Prod Sci.
  • 2019 Jun;25(2):136-142.
  • doi: 10.20307/nps.2019.25.2.136
Ischemia/reperfusion-induced myocardial injury is the main cause of acute myocardial infarction. Dendropanax morbifera Léveille has been used in traditional medicines for the treatment of various diseases such as headache, infectious...
Chemical Constituents of Impatiens balsamina Stems and Their Biological Activities

Kim DH, Lee TH, Subedi L, Kim SY, Lee KR

  • Nat Prod Sci.
  • 2019 Jun;25(2):130-135.
  • doi: 10.20307/nps.2019.25.2.130
The purification of the MeOH extract from Impatiens balsamina by repeated column chromatography led to the isolation of one new tetrahydronaphthalene (1), together with eleven known compounds (2 – 12)....
Quantitation and Radical Scavenging Activity Evaluation of Iridoids and Phenylethanoids from the Roots of Phlomis umbrosa (Turcz.) using DPPH Free Radical and DPPH-HPLC Methods, and their Cytotoxicity

Le DD, Nguyen DH, Zhao BT, Min BS, Song SW, Woo MH

  • Nat Prod Sci.
  • 2019 Jun;25(2):122-129.
  • doi: 10.20307/nps.2019.25.2.122
The roots of Phlomis umbrosa (Turcz.) (Phlomidis Radix) have been traditionally used to treat cold, reduce swelling and staunch bleeding. Four iridoids (1 – 3 and 5) and six phenylethanoid...
Chemical Constituents from Solenostemma argel and their Cholinesterase Inhibitory Activity

Demmak RG, Bordage S, Bensegueni A, Boutaghane N, Hennebelle T, Mokrani EH, Sahpaz S

  • Nat Prod Sci.
  • 2019 Jun;25(2):115-121.
  • doi: 10.20307/nps.2019.25.2.115
Alzheimer's disease is a chronic neurodegenerative disorder with no curative treatment. The commercially available drugs, which target acetylcholinesterase, are not satisfactory. The aim of this study was to investigate the...
Simultaneous Analysis of Four Standards of The Herbal Formula, DF-02, of Ephedra intermedia and Rheum palmatum, using by High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD)

Choi SY, Jeong B, Jang HS, Lee J, Kwon YS, Yoon Y, Shin SS, Yang H

  • Nat Prod Sci.
  • 2019 Jun;25(2):111-114.
  • doi: 10.20307/nps.2019.25.2.111
The herbal formula, DF-02, consisting of Ephedra intermedia and Rheum palmatum are used for the treatment of the metabolic diseases such as obesity and liver fibrosis in Korean local clinics....
Effect of Pyunkang-tang on Inflammatory Aspects of Chronic Obstructive Pulmonary Disease in a Rat Model

Seo HS, Lee HJ, Lee CJ

  • Nat Prod Sci.
  • 2019 Jun;25(2):103-110.
  • doi: 10.20307/nps.2019.25.2.103
We investigated the anti-inflammatory effect of Pyunkang-tang extract (PGT), a complex herbal extract based on traditional Chinese medicine that is used in Korea for controlling diverse pulmonary diseases, on cigarette...
The Potential of Centella asiatica (Linn.) Urban as an Anti-Microbial and Immunomodulator Agent: A Review

Harun NH, Septama AW, Wan Ahmad , Suppian R

  • Nat Prod Sci.
  • 2019 Jun;25(2):92-102.
  • doi: 10.20307/nps.2019.25.2.92
Centella asiatica (Linn.) Urban (Umbelliferae) which is also known as ‘pegaga’ is highly consumed and eaten raw as ‘ulam’ in Malaysia. C. asiatica is used in traditional medicines to treat...
Essential Oil of Marrubium vulgare: Chemical Composition and Biological Activities. A Review

Yabrir B

  • Nat Prod Sci.
  • 2019 Jun;25(2):81-91.
  • doi: 10.20307/nps.2019.25.2.81
Marrubium vulgare, plant species belonging to Marrubium genus, is widespread in the Mediterranean areas, introduced elsewhere and also cultivated in many countries. Its oil is recognized to possess a considerable...

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