Korean J Anesthesiol.  1994 Dec;27(12):1779-1785. 10.4097/kjae.1994.27.12.1779.

The Addition of Subarachnoid Fentanyl to Hyperbaric Bupivacaine with Morphine for Cesarean Section

• Son SC
• Yoon SH
• Shin YS
• Kim HJ
• Choi SJ

• KMID: 2240463
• DOI: http://doi.org/10.4097/kjae.1994.27.12.1779

Abstract

To investigate the effect of intrathecal fentanyl,36 ASA physieal status 1 or 2 parturients who underwent cesarean section with apinal anesthesis using 0.25% bupivacaine in 5.0% dextroae with 0.25mg morphine were studied. Patients were randomly allocated to receive either saline 0.2ml (group 1, n=17) or fentanyl 10ug(group 2, n=19) in 3.525ml volume mixed with the bupivacaine with morphine. Spinal anesthesia was performed in sitting position using a 25 guage spinal needle. At the completion of injection, patients immediately turned supine with left uterine diaplacement. There was no statistically significant difference in the incidence of the hypotension between groups. The progress of sensory and motor blocks was similar in the two groups. The times from drug injection ta the onset to maximal sensory blockade and complete motor blockade, complete recovery of sensation and motor power were not different between groups. post delivery,the incidence of visceral pain were significantly less in group 2, as 2 of 19 patients(10%) in group 2 compared to 8 of 17 patients(47%) in group 1(p< 0.05). The effective analgesia time was no significant different: 31.7+/-2.5 hour in group 1 compared to 28.6+/-5.6 hour in Group 2. The ineidence of patients not requiring narcotics until discharge was similar in two groups. No patient showed any evidence of respiratory depression. The incidence of other side effects,such as nausea,vomiting and pruritus was not different between groups. No neonate had an Apgar score below 7.

Keyword

Spinal Anesthesie; Bupivacaine; Fentanyl; Morphine

MeSH Terms

Analgesia
Anesthesia, Spinal
Apgar Score
Bupivacaine*
Cesarean Section*
Female
Fentanyl*
Humans
Hypotension
Incidence
Infant, Newborn
Morphine*
Narcotics
Needles
Pregnancy
Pruritus
Respiratory Insufficiency
Sensation
Visceral Pain
Bupivacaine
Fentanyl
Morphine
Narcotics