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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Sevoflurane with opioid or dexmedetomidine infusions in dogs undergoing intracranial surgery: a retrospective observational study

Marquez-Grados F, Vettorato , Corletto F

This study reports the clinical use of two sevoflurane-based anesthetic techniques in dogs undergoing craniectomy. Twenty-one animals undergoing elective rostrotentorial or transfrontal craniectomy for brain tumor excision, anesthetized with sevoflurane,...
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Impacts of Coronary Artery Calcification on Intradialytic Blood Pressure Patterns in Patients Receiving Maintenance Hemodialysis

Yeo S, Moon JI, Shin J, Hwang JH, Cho I, Kim SH

Intradialytic blood pressure abnormalities are associated with adverse outcomes in patients with end-stage renal disease on dialysis. Vascular calcification is a common complicating feature, but whether this complication results in...
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Incidence of Hypotension after Discontinuation of Norepinephrine or Arginine Vasopressin in Patients with Septic Shock: a Systematic Review and Meta-Analysis

Song JU, Lee J, Park HK, Suh GY, Jeon K

BACKGROUND: There has been no consensus regarding the discontinuation order of vasopressors in patients recovering from septic shock treated with concomitant norepinephrine (NE) and arginine vasopressin (AVP). The aim of...
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Short-term hemodynamic response to calcium supplementation in patients with refractory septic shock: a retrospective observational study

Chang HS, Hwang SY, Park JE, Kim T, Park JH, Yoon H, Cha WC, Sim MS, Jo IJ, Shin TG

OBJECTIVE: Research on calcium use as an adjunctive rescue therapy for refractory septic shock is limited. In this study, we aimed to investigate the short-term hemodynamic response after calcium supplementation...
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Age group characteristics of clinical features and use of epinephrine in children with anaphylaxis who visited the emergency department

Baek N, Lee JS, Ryu JM

PURPOSE: Diagnosis of anaphylaxis depends on clinical manifestations and a high index of suspicion, and a misdiagnosis can lead to a preventable death. We aimed to investigate age group characteristics...
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A Prospective, Multicenter, Open-Label Study of Dose Escalation Therapy in Male Patients With Nocturia Refractory to 0.2-mg Tamsulosin Monotherapy

Yu HS, Lee JW, Yu J, Cho MC, Cho SY

PURPOSE: To investigate the efficacy and safety of 0.4 mg of tamsulosin in patients with nocturia not responding to 0.2 mg. METHODS: Patients with intractable nocturia after treatment with 0.2 mg...
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Susceptibility-Weighted MR Imaging for the Detection of Isolated Cortical Vein Thrombosis in a Patient with Spontaneous Intracranial Hypotension

Kwon H, Choi DS, Jang J

Spontaneous intracranial hypotension (SIH) can be a rare risk factor of cerebral venous thrombosis. We describe a case of isolated cortical vein thrombosis (CVT) secondary to SIH and discuss the...
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Efficacy of minimal invasive cardiac output and ScVOâ‚‚ monitoring during controlled hypotension for double-jaw surgery

Kim S, Song J, Ji S, Kwon MA, Nam D

BACKGROUND: Controlled hypotension (CH) provides a better surgical environment and reduces operative time. However, there are some risks related to organ hypoperfusion. The EV1000/FloTrac system can provide continuous cardiac output...
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Ideal Target Blood Pressure in Hypertension

Park S

In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive blood pressure (BP) lowering was associated with significant reduction in composite cardiovascular (CV) outcomes in hypertension. Subsequently, several meta-analyses have corroborated...
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Use of methylene blue in vasoplegic syndrome that developed during non-cardiac surgery: A case report

Oh ID, Shin E, Jeon JM, Woo H, Choi JH

BACKGROUND: Vasoplegic syndrome is an increasingly recognized disease in perioperative medicine and is characterized by severe hypotension, normal or elevated cardiac output, and decreased systemic vascular resistance. It occurs commonly...
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Anaphylactic reaction with hydroxyethyl starch during anesthesia: A case report

Kim G, Kim G, Kwon M, Koo M, Yun M

BACKGROUND: Hydroxyethyl starch (HES), a class of synthetic colloid solutions, has been widely used to treat perioperative hypovolemia. The use of HES, however, is associated with the risk of allergic...
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Adverse events of conscious sedation using midazolam for gastrointestinal endoscopy

Jun J, Han JI, Choi AL, Kim YJ, Lee JW, Kim DY, Lee M

BACKGROUND: This study was conducted to identify the types and incidence of adverse events associated with midazolam, which is the most widely used drug to induce conscious sedation during gastrointestinal...
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Cervical Cerebrospinal Fluid Leakage Concomitant with a Thoracic Spinal Intradural Arachnoid Cyst

Han S, Choi SW, Park BS, Lim JW, Kim SH, Youm JY

We encountered a very rare case of spontaneous spinal cerebrospinal fluid (CSF) leakage and a spinal intradural arachnoid cyst (AC) that were diagnosed at different sites in the same patient....
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Risk Factors and Causes of Short-Term Mortality after Emergency Department Discharge in Older Patients: Using Nationwide Health Insurance Claims Data

Na S, Cho Y, Lim TH, Kang H, Oh J, Ko BS

BACKGROUND: The purpose of this study was to identify the risk factors and causes of short-term mortality after emergency department (ED) discharge in older patients. METHODS: This population-based cohort study used...
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Levothyroxine Sodium Administration and Late Circulatory Collapse in Premature Infants with Thyroid Dysfunction

Do HJ, Cho JY, Yeom JS, Park JS, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

OBJECTIVE: Levothyroxine sodium (LT4) is considered safe, and widely administered to premature infants with thyroid dysfunction. Late circulatory collapse (LCC) has not been defined clearly, but it has been characterized...
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Safety Issues with Sodium-Glucose Cotransporter 2 Inhibitors: Clinical Considerations

Lim S

Diabetes mellitus (DM) is linked to poor outcomes after cardiovascular events and renal complications. Recently, novel antidiabetic agents, such as dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter 2 (SGLT2) inhibitors, and glucagon-like...
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Subcapsular Splenic Hemorrhage in Vivax Malaria

Im JH, Chung MH, Durey A, Lee JS, Kim TS, Kwon HY, Baek JH

In malaria, splenic rupture is a serious complication potentially leading to death. Subcapsular hemorrhage of spleen is thought to be an impending sign of splenic rupture; however, the characteristics of...
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Clinical Features of Late-Onset Circulatory Collapse in Preterm Infants

Jang JH, Shin J, Jung YH, Choi CW, Kim BI

PURPOSE: This study aimed to investigate the incidence and clinical features of late-onset circulatory collapse (LCC) in preterm infants. METHODS: Medical records of 327 preterm infants (born before 32 gestational weeks)...
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Risk Factors for Adverse Events of Therapeutic Plasma Exchange Assessed in a Single Center Study

Park CG, Lee AJ, Mun SH, Kim SG, Jeon CH, Suh HS

BACKGROUND: Therapeutic plasma exchange (TPE) is used to remove pathologic substances involved in various disease etiologies. The use of TPE is increasing steadily in a variety of disease. This study...
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