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Association of preoperative pain in knee and external to knee with postoperative pain outcome after total knee arthroplasty

Oh TK, Chang CB, Shin HJ, Han S, Do SH, Cho HH, Hwang JW

BACKGROUND: Preoperative pain in the symptomatic knee may predict postoperative pain severity in patients undergoing total knee arthroplasty (TKA). However, the effect of preoperative pain external to the knee on...
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The analgesic efficacy of the transversalis fascia plane block in iliac crest bone graft harvesting: a randomized controlled trial

Black ND, Malhas L, Jin R, Bhatia A, Chan VW, Chin KJ

BACKGROUND: Iliac crest bone graft (ICBG) harvesting is associated with significant perioperative pain and opioid consumption. This randomized controlled trial sought to determine if the transversalis fascia plane (TFP) block...
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Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
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Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial

Hashem A, Ghobrial F, Elbaset MA, Atwa AM, Fadallah M, Laymon M, El-Assmy A, Sheir KZ, Abol-Enein H

PURPOSE: To compare the safety and efficacy of xylocaine gel and ketorolac as opioid-sparing analgesia compared with pethidine for shock wave lithotripsy (SWL) pain. MATERIALS AND METHODS: A single-blinded randomized controlled...
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Small dose of naloxone as an adjuvant to bupivacaine in intrapleural infiltration after thoracotomy surgery: a prospective, controlled study

Amer AF, Omara AF

BACKGROUND: Severe pain always develops after thoracotomy; intrapleural regional analgesia is used as a simple, safe technique to control it. This study was performed to evaluate whether a small dose...
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Fluoroscopic Characterization of Colonic Dysmotility Associated to Opioid and Cannabinoid Agonists in Conscious Rats

Díaz-Ruano S, López-Pérez AE, Girón R, Pérez-García I, Martín-Fontelles MI, Abalo R

  • KMID: 2449102
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):300-315.
  • doi: 10.5056/jnm18202
BACKGROUND/AIMS: Gastrointestinal adverse effects have a major impact on health and quality of life in analgesics users. Non-invasive methods to study gastrointestinal motility are of high interest. Fluoroscopy has been...
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Association between perioperative cholesterol level and analgesia after video-assisted thoracoscopic surgery

Oh TK, Kim K, Jheon S, Lee HJ, Do SH

BACKGROUND: Cholesterol plays an important role in the action of opioid analgesics, but its association with postoperative pain has not been clarified. Our study examined the association of pre- and...
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The Effect of Cervical Stellate Ganglion Block Using Botulinum Toxin Type A in Intractable Cancer-related Pain: Case Report

Sohn D, Park GY, Im S, Jeon SH, Choi Y

OBJECTIVE: For patients who do not relieve with pharmacological intervention, interventional treatment including neurolytic blocks may have a specific role in palliative cancer management. METHOD: We performed cervical stellate ganglion block...
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The Effectiveness of Ultrasound-Guided Thoracic Paravertebral Block for Percutaneous Radiofrequency Ablation of Hepatic Tumors: A Pilot Study

Kim H, Kim Y, Kim BJ, Shin SI, Yim SM, Lee JH

PURPOSE: The purpose of this study was to evaluate the effectiveness of thoracic paravertebral block (TPVB) for management of pain during and after percutaneous radiofrequency ablation (RFA) of hepatic tumor. MATERIALS...
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Effect of Surgical-Site, Multimodal Drug Injection on Pain and Stress Biomarkers in Patients Undergoing Plate Fixation for Clavicular Fractures

Yoo JS, Heo K, Kwon SM, Lee DH, Seo JB

BACKGROUND: Surgical-site, multimodal drug injection has recently evolved to be a safe and useful method for multimodal pain management even in patients with musculoskeletal trauma. METHODS: Fifty consecutive patients who underwent...
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Comparison of Preoperative and Postoperative Parecoxib Administration for Pain Control Following Major Spine Surgery

Moonla R, Threetipayarak A, Panpaisarn C, Pattayaruk N, Kaewkam U, Jumpalee N, Panwilai J

STUDY DESIGN: Prospective randomized, double-blind controlled trial. PURPOSE: Here, we aim to compare the efficacy and safety of pain control between pre- and postoperative parecoxib administration in patients who have undergone...
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Comparison of patient-controlled epidural analgesia with patient-controlled intravenous analgesia for laparoscopic radical prostatectomy

Hwang BY, Kwon JY, Jeon SE, Kim ES, Kim HJ, Lee HJ, An J

BACKGROUND: Patient-controlled epidural analgesia (PCEA) is known to provide good postoperative analgesia in many types of surgery including laparoscopic surgery. However, no study has compared PCEA with patient-controlled intravascular analgesia...
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Postoperative Fever Evaluation Following Lumbar Fusion Procedures

Mayo BC, Haws BE, Bohl DD, Louie PK, Hijji FY, Narain AS, Massel DH, Khechen B, Singh K

OBJECTIVE: This study aimed to determine the incidence of postoperative fever, the workup conducted for postoperative fever, the rate of subsequent fever-related diagnoses or complications, and the risk factors associated...
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Initial titration with 200 μg fentanyl buccal tablets: a retrospective safety analysis in Korean cancer patients

Kwon MY, Cho HN, Koo DH, Lee YG, Oh S, Lee SS

BACKGROUND/AIMS: Managing breakthrough pain (BTP) is important for many cancer patients because of the rapid onset and unpredictable nature of the pain episodes. Fentanyl buccal tablets (FBTs) are a rapid-onset...
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Intrathecal baclofen pump implantation for complex regional pain syndrome in a patient with a spinal cord stimulator: consideration about optimal location of intrathecal catheter tip: A case report

Ko MJ, Lee HS, Jo H, Kim SR, Jeon S, Lee SE

Intrathecal baclofen (ITB) pump implantation can be used to control dystonia and severe pain associated with complex regional pain syndrome (CRPS) with or without a spinal cord stimulator (SCS). A...
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Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after gynecologic laparoscopic surgery: a randomized controlled study

Platon B, Mannheimer C, Andréll P

BACKGROUND: The aim of the study was to compare the pain relieving effect and the time spent in the recovery unit after treatment with high frequency, high-intensity transcutaneous electrical nerve...
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Morphine-alcohol treatment impairs cognitive functions and increases neuro-inflammatory responses in the medial prefrontal cortex of juvenile male rats

Adedayo AD, Aderinola , Adekilekun TA, Olaolu OO, Olanike AM, Olayemi IK

In the developed and developing world, opioid consumption in combination with alcohol has become one of the substances abused. In this experiment, we examined the effects of alcohol, morphine, and...
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Factors Influencing Pain Medication Preference for Breakthrough Cancer Patients and Their Application to Treatments: Survey on Physicians

Shin J, Shim JY, Seo MS, Kim DY, Lee J, Hwang IG, Baek SK, Choi YS

PURPOSE: The purpose of this study was to assess the factors influencing the rescue medication decisions for breakthrough cancer patients and evaluate treatments using the factors. METHODS: Based on the results...
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Does Subcutaneous Infiltration of Liposomal Bupivacaine Following Single-Level Transforaminal Lumbar Interbody Fusion Surgery Improve Immediate Postoperative Pain Control?

Tomov M, Tou K, Winkel R, Puffer R, Bydon M, Nassr A, Huddleston P, Yaszemski , Currier B, Freedman B

STUDY DESIGN: Retrospective case-control study using prospectively collected data. PURPOSE: Evaluate the impact of liposomal bupivacaine (LB) on postoperative pain management and narcotic use following standardized single-level low lumbar transforaminal lumbar...
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Morphine as a suspect of aiding the propagation of cancer cells

Shin Y

Controlling pain in cancer patients is important for several reasons including patient quality of life (QOL). In moderate-to-severe cancer-pain management, opioid analgesics are indispensable. Among these, morphine is the most...
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