Infect Chemother.  2014 Dec;46(4):269-273. 10.3947/ic.2014.46.4.269.

A Case of Disseminated Infection due to Actinomyces meyeri Involving Lung and Brain

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. soleemd@amc.seoul.kr
  • 2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Abstract

Actinomyces meyeri is rarely isolated in cases of actinomycosis. The identification of A. meyeri had historically been difficult and unreliable. With the recent development of 16S ribosomal RNA (16S rRNA) sequencing, Actinomyces species such as A. meyeri can be isolated much more reliably. A. meyeri often causes disseminated disease, which can be secondary to frequent pulmonary infections. A penicillin-based regimen is the mainstay of A. meyeri treatment, with a prolonged course usually required. Here, we report a case of pulmonary actinomycosis with brain abscess caused by A. meyeri that was initially thought to represent lung cancer with brain metastasis.

Keyword

Actinomyces; Sequence analysis; RNA; Brain abscess

MeSH Terms

Actinomyces*
Actinomycosis
Brain Abscess
Brain*
Lung Neoplasms
Lung*
Neoplasm Metastasis
RNA
RNA, Ribosomal, 16S
Sequence Analysis
RNA
RNA, Ribosomal, 16S
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