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The different prognostic impact of age according to individual molecular subtypes in breast cancer

Kim NH, Bang HW, Eom YH, Choi SH

Purpose: Young age at diagnosis has been considered a poor prognostic factor. However, considering young age itself as an independent poor prognostic factor for all breast cancers is unwarranted. We...
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A New Modality in Dyslipidemia Treatment: Antisense Oligonucleotide Therapy

Kim K, Choi SH

There are unmet needs for pharmacologic agents beyond current medications, such as statins, to effectively lower low-density lipoprotein cholesterol levels to target goals, especially in patients with very high or...
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2022 Consensus Statement on the Management of Familial Hypercholesterolemia in Korea

Lee CJ, Yoon M, Kang HJ, Kim BJ, Choi SH, Jeong IK, Lee SH, oboTFTfFHKSoLaA

Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical. Herein,...
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The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study

Ko KA, Park JY, Lee JS, Ye BS, Jung UW, Choi SH, Cha JK

Purpose: The aim of this study was to investigate the association between the changes in masticatory function and cognitive impairment by analyzing longitudinal data of older Korean patients. Materials and Methods:...
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Effects of outdoor air pollution on children with allergic rhinitis

Sung M, Kim M, Kim HH, Rha YH, Park Y, Park YM, Sheen YH, Yum HY, Lee KS, Lee YJ, Chun YH, Jee HM, Choi BS, Choi SH, Kim HB, ftRSGitKAoPAaRD

The global worsening of air pollution has decreased the quality of life. Air pollutants can induce oxidative stress, epigenetic changes, and alterations to microRNA expression in the airway and skin,...
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Local Drug Delivery Strategies for Glioblastoma Treatment

Cha GD, Jung S, Choi SH, Kim DH

Glioblastoma multiforme (GBM) is a brain tumor notorious for its malignancy. The key reason for the limited efficacy of standard treatment is the high recurrence rate of GBM, even after...
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Validation of three-dimensional digital model superimpositions based on palatal structures in patients with maximum anterior tooth retraction following premolar extraction

Liu J, Koh KM, Choi SH, Kim JH, Cha JY

Objective: This study aimed to evaluate the superimposition accuracy of digital modes for measuring tooth movement in patients requiring anterior retraction after premolar extraction based on the proposed reference regions. Methods:...
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Shift in Clinical Epidemiology of Human Parainfluenza Virus Type 3 and Respiratory Syncytial Virus B Infections in Korean Children Before and During the COVID-19 Pandemic: A Multicenter Retrospective Study

Kim YK, Song SH, Ahn B, Lee JK, Choi JH, Choi SH, Yun KW, Choi EH

Background: Parainfluenza virus type 3 (PIV3) and respiratory syncytial virus (RSV) B epidemics occurred in South Korea in late 2021. We investigated epidemiological changes of PIV3 and RSV B infections...
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A Multinational, Multicenter, Randomized, Double-Blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer’s Disease

Han HJ, Park MY, Park KW, Park KH, Choi SH, Kim HJ, Yang DW, Ebenezer EGAM, Yang YH, Kewalram GM, Han SH, oBtI3S

Background and Purpose Oral administration of cholinesterase inhibitors is often associated with adverse gastrointestinal effects, and so developing an alternative administration route, such as transdermal, is urgently needed. The primary...
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Long-Term Clinical Outcomes of Iliac Artery Endovascular Therapy in the Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases (K-VIS ELLA) Registry

Roh JW, Shin S, Ko YG, Son NH, Ahn CM, Min PK, Lee JH, Yoon CH, Yu CW, Lee SW, Lee SR, Choi SH, Chae IH, Choi D

Background and Objectives: Limited data are available regarding long-term clinical outcomes of iliac artery endovascular therapy (EVT) in real-world practice. This study investigated long-term outcomes according to Trans-Atlantic Inter-Society Consensus...
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Decellularized Non-cross-linked Collagen Membranes for Guided Bone Regeneration in Rabbit Calvarial Defects

Jeon SH, Lee DN, Seo YW, Park JY, Paik JW, Cha JK, Choi SH

Purpose: The aim of this study was to evaluate the bio-durability and bone regeneration capacity of the non-crosslinked collagen membrane in rabbit calvarial defect models. Materials and Methods: Four circular defects...
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Antiviral Resistance in Human Cytomegalovirus Due to UL54 Mutations Without UL97 Mutations

Park K, Hur KH, Sung H, Choi SH, Kim MN

Background: The concurrent detection of human cytomegalovirus (CMV) with UL97 and UL54 mutations is crucial for prescribing adequate antiviral treatment when drug-resistant CMV infection is suspected. We investigated the frequency...
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The Changes in Epidemiology of Imipenem-Resistant Acinetobacter baumannii Bacteremia in a Pediatric Intensive Care Unit for 17 Years

Kim D, Lee H, Choi Js, Croney CM, Park KS, Park HJ, Cho J, Son S, Kim JY, Choi SH, Huh HJ, Ko KS, Lee NY, Kim YJ

Background: Acinetobacter baumannii infections cause high morbidity and mortality in intensive care unit (ICU) patients. However, there are limited data on the changes of longterm epidemiology of imipenem resistance in...
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Long-term Clinical Outcomes and Prognostic Factors After Endovascular Treatment in Patients With Chronic Limb Threatening Ischemia

Cha JJ, Kim JY, Kim H, Ko YG, Choi D, Lee JH, Yoon CH, Chae IH, Yu CW, Lee SW, Lee SR, Choi SH, Koh YS, Min PK, on behalf of the K-VIS (Korean Vascular Intervention Society) investigators

Background and Objectives: Endovascular therapy (EVT) first strategy has been widely adopted for the treatment of chronic limb threatening ischemia (CLTI) patients in realworld practice. This study aimed to investigate...
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Correction: A Bone Metastasis Nude Mouse Model Created by Ultrasound Guided Intracardiac Injection of Breast Cancer Cells: the Micro-CT, MRI and Bioluminescence Imaging Analysis

Park YJ, Song EH, Kim SH, Choi SH, Song HT, Suh JS

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Effects of Local Anesthetics With or Without Steroids in High-Volume Transforaminal Epidural Blocks for Lumbar Disc Herniation: A Randomized, Double-Blind, Controlled Trial

Chae JS, Kim Wj, Choi SH

Background: Lumbar transforaminal epidural block (TFEB) is an effective treatment modality for radicular pain due to lumbar disc herniation (LDH). The addition of steroids is more effective than local anesthetic...
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Cumulative Recurrence Rate and Risk Factors for Recurrent Abdominal Wall Endometriosis after Surgical Treatment in a Single Institution

Kim SJ, Choi SH, Won S, Shim S, Lee N, Kim M, Kim MK, Seong SJ, Kim ML

Purpose: This study aimed to evaluate the cumulative recurrence rate and risk factors for recurrent abdominal wall endometriosis (AWE) after surgical treatment. Materials and Methods: A retrospective cohort study was conducted...
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Impact of the Liver Imaging Reporting and Data System on Research Studies of Diagnosing Hepatocellular Carcinoma Using MRI

Ahn Y, Choi SH, Jang JK, Kim SY, Shim JH, Lee SS, Byun JH

Objective: Since its introduction in 2011, the CT/MRI diagnostic Liver Imaging Reporting and Data System (LI-RADS) has been updated in 2014, 2017, and 2018. We evaluated the impact of CT/MRI...
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Efficacy and Safety of COVID-19 Vaccines in Children Aged 5 to 11 Years: A Systematic Review

Choi M, Yu SY, Cheong C, Choe YJ, Choi SH

Purpose: To evaluate the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccines in children aged 5–11 years, a rapid systematic review was conducted on published clinical trials of COVID-19...
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Risk factors and protective factors in pediatric patients with allergic rhinitis

Chun YH, Kim M, Kim HB, Rha YH, Park Y, Park YM, Sung M, Shin YH, Yum HY, Lee KS, Lee YJ, Jee HM, Choi BS, Choi SH, Kim HH, for the Rhinitis Study Group in the Korean Academy of Pediatric Allergy and Respiratory Diseases

Among allergic diseases of the Korean pediatric population, allergic rhinitis shows the most rapidly increasing prevalence. Its economic burden is substantial in many Asian countries including South Korea. This investigation...
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