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Discontinuation Rate of Newly Prescribed Donepezil in Alzheimer’s Disease Patients in Asia

Park KH, Yang Y, Chen C, Shim YS, Dominguez JC, Lee CN, Kang K, Kim HJ, Jeong SK, Jeong JH, Hong Z, Yoon SJ, Zhang ZX, Kim EJ, Jang JW, Li Y, Xu Y, Lin YT, Qu Q, Hu CJ, Chou CH, Fan D, Kandiah N, Yang YH, Lau Ci, Chu LW, Wang H, Jung S, Choi SH, Kim S

Background and Purpose The rate of donepezil discontinuation and the underlying reasons for discontinuation in Asian patients with Alzheimer’s disease (AD) are currently unknown. We aimed to determine the treatment...
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Impact of an Education Program for Caregivers of Patients with Alzheimer’s Disease on Treatment Discontinuation and Compliance in Korea

Kim HJ, Shim YS, Park KH, Lee CN, Jung S, Yoon SJ, Jeong SK, Jeong JH, Choi SH, Kim EJ, Jang JW, Kang K, Yang Y, Kim S

Background and Purpose: Reportedly 30–50% of patients being treated for chronic illnesses do not adhere to their medication regimen. We assessed the impact of a nurse-led education program for caregivers...
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Downregulation of MicroRNA-495 Alleviates IL-1β Responses among Chondrocytes by Preventing SOX9 Reduction

Joung S, Yoon DS, Cho S, Ko EA, Lee KM, Park KH, Lee JW, Kim SH

Purpose: Our previous work demonstrated that miRNA-495 targets SOX9 to inhibit chondrogenesis of mesenchymal stem cells. In this study, we aimed to investigate whether miRNA-495-mediated SOX9 regulation could be a novel...
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Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease

Song JH, Kim GT, Park KH, Park WJ, Park TS

  • KMID: 2517155
  • Biomol Ther.
  • 2021 Jul;29(4):373-383.
Atherosclerosis is the deposition of plaque in the main arteries. It is an inflammatory condition involving the accumulation of macrophages and various lipids (low-density lipoprotein [LDL] cholesterol, ceramide, S1P). Moreover,...
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Academic  Stress  and  Its  Influencing  Factors  among  Medical  and  Non‐Medical  Students

Seong A, Heo S, Yoon J, Lee JY, Choi MG, Jeon Jh, Kim JH, Park KH, Im JS, Ko KP, Jung J, Choi YH

This study examined the relationships among personality traits, coping efficacy, and academic stress in medical and non-medical students in South Korea, and investigated the mediating effect of coping efficacy in...
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Q‐Methodology  Study  on  Medical  Students’ Perceptions  of  Good  Jobs

Lee J, Park KH

This study investigated medical students’ perceptions of good jobs. We classified medical students’ perceptions of good jobs and analyzed the characteristics of each type. The Q methodology was used to...
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Source Analysis and Effective Control of a COVID-19 Outbreak in a University Teaching Hospital during a Period of Increasing Community Prevalence of COVID-19

Lee U, Kim SE, Lee SY, Wi HN, Choi O, Park JW, Kim D, Kim YJ, Shin HY, Kim M, Kim EJ, Kang SJ, Jung SI, Park KH

Background: South Korea has been experiencing a third wave of coronavirus disease 2019 (COVID-19) since mid-November 2020. Our hospital in Gwangju metropolitan city experienced a healthcare-associated COVID-19 outbreak early in...
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Treatment of Recurrent Hemarthrosis Following Total Knee Arthroplasty Using Surgical Interventions

Park KH, Kim DH, Jang SW, Ryu JH, Ko KY

Background: Recurrent hemarthrosis following total knee arthroplasty (TKA) is a rare complication. Its pathophysiology and standard treatments have not yet been established. In this study, we report 7 cases of...
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Association between Hearing Loss and Cognitive Disorder: A Nationwide Population-Based Study

Lee HJ, Joo YH, Han Kd, Park KH

Purpose: To investigate the relationship between hearing loss and cognitive disorder with memory dysfunction in South Korea using data from the Korean Health Insurance claims database for 2009–2015. Materials and Methods:...
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Treatment of Malunion

Kim JW, Park KH, Oh CW

Although current surgical techniques have reduced the incidence of malunion, it is still observed because of the complexity of the fracture or associated injuries. Osteotomy is needed when the amount...
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Long-term Outcome of Microscopic Transsphenoidal Surgery for Prolactinomas as an Alternative to Dopamine Agonists

Park K, Park KH, Park HR, Lee JM, Kim YH, Kim DY, Won TB, Kong SH, Kim JH, Shin CS, Paek SH

Background: Although long-term dopamine agonist (DA) therapy is recommended as a first-line treatment for prolactinoma, some patients may prefer surgical treatment because of the potential adverse effects of long-term medication,...
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Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006)

Ahn SG, Nam SJ, Ahn SH, Jung Y, Park HK, Lee SJ, Kang SS, Han W, Park KH, Park YL, Lee J, Youn HJ, Kim JH, Yoo Y, Song JY, Ko BK, Gwak G, Chung MS, Kim SY, Cho SH, Kim D, Chang MC, Moon BI, Kim LS, Kim SJ, Park MH, Kim TH, Cho J, Lim CW, Bae YT, Gong G, Bae YK, Lee A, Jeong J

Purpose: In this trial, we investigated the efficacy and safety of adjuvant letrozole for hormone receptor (HR)-positive breast cancer. Here, we report the clinical outcome in postmenopausal women with HR-positive...
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Etiology, Characteristics, and Outcomes of Community-Onset Pyomyositis in Korea: A Multicenter Study

Kim T, Park SY, Kwak YG, Jung J, Kim MC, Choi SH, Yu SN, Hong HL, Kim YK, Park SY, Song EH, Park KH, Cho OH, Choi SH, TKSSG

Background: Pyomyositis (PM) is a serious soft tissue infection and despite its clinical importance, previous studies have not been able to fully determine the clinical characteristics and microbial epidemiology of...
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Machine-Learning-Based Approach to Differential Diagnosis in Tuberculous and Viral Meningitis

Jeong YS, Jeon M, Park JH, Kim MC, Lee E, Park SY, Lee YM, Choi S, Park SY, Park KH, Kim SH, Jeon MH, Choo EJ, Kim TH, Lee MS, Kim T

Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis, but differentiating between the diagnosis of TBM and viral meningitis (VM) is difficult. Thus, we have developed machine-learning modules...
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Validation of a New Screening Tool for Dementia: The Simple Observation Checklist for Activities of Daily Living

Park J, Choi H, Jang JW, Lim JS, Yang Y, Lee CN, Park KH

Background and Purpose Screening tests for dementia such as the Mini Mental State Examination (MMSE) and the Montreal Cognitive Assessment are widely used, but there are drawbacks to their efficient...
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Comparison of Allergenic Properties among Commercially Available House Dust Mite Allergen Extracts in Korea

Kim JT, Kim H, Kim SH, Kim DJ, Shin Y, Kim JD, Song H, Jang SW, Lee Dc, Park KH, Lee JH, Jeong KY, Park JW

Precise allergy diagnosis and effective allergen specific immunotherapy are largely dependent on the quality of allergen extract. A new extract of Dermatophagoides farinae was commercially developed by Prolagen. The allergenic...
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Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients

Bae H, Na DH, Chang JY, Park KH, Min JW, Ko EJ, Lee H, Yang CW, Chung BH, Oh EJ

Background/Aims To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods We...
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Usefulness of Reference Change Values for Delta Check Limits in Clinical Laboratory Testing

Lee S, Son JO, Kwon H, Park KH, Yu GG, Han E, Jekarl DW, Kim Y

Background: In this study, the usefulness of within-subject biological coefficient of variation (CVI) and reference change values (RCVs) for delta check limits were investigated by comparing the population distributionbased delta...
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Bioequivalence of the pharmacokinetics between tofacitinib aspartate and tofacitinib citrate in healthy subjects

Shin W, Yang AY, Yun H, Cho DY, Park KH, Shin H, Kim A

Tofacitinib is an oral disease-modifying anti-rheumatic drug to selectively inhibit Janus kinases. Tofacitinib is a representative small molecule inhibitor that is used to treat many diseases including rheumatoid arthritis and...
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Negative school experiences of Late Millennial Korean medical students: a qualitative study using the critical incident technique

Roh H, Yune SJ, Park KH, Lee GH, Jung SS, Chun KH

Purpose: Today's students have distinctive generational characteristics and increased psychopathology and generational tension. The authors investigated the negative experiences of Late Millennial students in medical school to draw implications for...
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