J Korean Neurol Assoc.
2005 Oct;23(5):585-594.
Metabolic Syndrome and Stroke
- Affiliations
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- 1Department of Neurology, Ewha Womans University College of Medicine, Ewha Medical Research Center, Seoul, Korea. brain930@ewha.ac.kr
Abstract
- Metabolic syndrome, comprising of abdominal obesity, elevated triglyceride levels, low levels of high-density lipoprotein cholesterol, elevated blood pressure, and impaired glucose metabolism, greatly increases the risk of cardiovascular disease, including stroke. The high prevalence of metabolic syndrome among individuals who experience stroke makes the metabolic syndrome a target for aggressive intervention and therapy. Primary intervention for stroke focuses on achievement of a healthy body weight and regular physical activity to prevent or correct dyslipidemia, insulin resistance, and high blood pressure. Statins favorably affect both lipid and nonlipid risk factors for stroke, making them a useful tool for stroke prevention.