- Correlation analysis of cancer incidence after pravastatin treatment
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Yu J, Kim R, Shinn J, Park MY, Kim HS
- KMID: 2541760
- Cardiovasc Prev Pharmacother.
- 2023 Apr;5(2):61-68.
- doi: 10.36011/cpp.2023.5.e6
Background: Few studies have investigated the cancer-preventive effects of statins, which are known to protect against cardio-cerebrovascular diseases. In this study, we analyzed the degree to which pravastatin, a low-potency... -
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- The Relationship between Delirium and Statin Use According to Disease Severity in Patients in the Intensive Care Unit
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An JY, Park JY, Cho J, Kim HE, Park J, Oh J
- KMID: 2539662
- Clin Psychopharmacol Neurosci.
- 2023 Feb;21(1):179-187.
- doi: 10.9758/cpn.2023.21.1.179
Objective: The aim of this study was to investigate the association between the use of statins and the occurrence of delirium in a large cohort of patients in the intensive... -
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- Low-Density Lipoprotein Cholesterol Level, Statin Use and Myocardial Infarction Risk in Young Adults
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Jeong H, Han K, Yoo SJ, Kim MK
- KMID: 2533266
- J Lipid Atheroscler.
- 2022 Sep;11(3):288-298.
- doi: 10.12997/jla.2022.11.3.288
Objective: The consequences of blood lipid abnormalities for cardiovascular disease risk in young adults is unclear. Optimal lipid levels may also vary depending on whether a statin drug is taken.... -
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- New, Novel Lipid-Lowering Agents for Reducing Cardiovascular Risk: Beyond Statins
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Kim K, Ginsberg HN, Choi SH
- KMID: 2531956
- Diabetes Metab J.
- 2022 Jul;46(4):517-532.
- doi: 10.4093/dmj.2022.0198
Statins are the cornerstone of the prevention and treatment of atherosclerotic cardiovascular disease (ASCVD). However, even under optimal statin therapy, a significant residual ASCVD risk remains. Therefore, there has been... -
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- Statin and aspirin for chemoprevention of hepatocellular carcinoma: Time to use or wait further?
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Goh MJ, Sinn DH
- KMID: 2531366
- Clin Mol Hepatol.
- 2022 Jul;28(3):380-395.
- doi: 10.3350/cmh.2021.0366
Preclinical studies highlighted potential therapeutic applications of aspirin and statins as anticancer agents based on their pleiotropic effects. Epidemiologic studies suggested the role of aspirin and statins in the chemoprevention... -
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- Evidence on Statins, Omega-3, and Prostate Cancer: A Narrative Review
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Kim H, Kim JK
- KMID: 2530709
- World J Mens Health.
- 2022 Jul;40(3):412-424.
- doi: 10.5534/wjmh.210139
Dietary intake selections might play a crucial role in prostate cancer (PCa) occurrence and progression. Several studies have investigated whether statin use could reduce PCa risk but with conflicting results.... -
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- Exploring the Genetic Associations Between the Use of Statins and Alzheimer's Disease
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Lee J, Park S, Kim Y, Kim HM, Oh CM
- KMID: 2531860
- J Lipid Atheroscler.
- 2022 May;11(2):133-146.
- doi: 10.12997/jla.2022.11.2.133
Objective: Alzheimer's disease (AD) is the most common cause of dementia. The statins have shown beneficial effects on cognitive functions and reduced the risk of dementia development. However, the exact... -
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- Impact of Statin Treatment Intensity after Endovascular Revascularization on Lower Extremity Peripheral Artery Disease
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Kim GS, Seo J, Kim BG, Jin MN, Lee HY, Kim BO, Byun YS
- KMID: 2527514
- Yonsei Med J.
- 2022 Apr;63(4):333-341.
- doi: 10.3349/ymj.2022.63.4.333
Purpose: Only a few Asian studies have discussed the impact of statin intensity on clinical outcomes in patients with peripheral artery disease (PAD). We aimed to investigate the clinical impact... -
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- A Prospective Single-Center Study of Incidence of Atorvastatin-Induced Myalgia in Korean Patients: Application of the Statin Myalgia Clinical Index
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Kang K, Kim BK
- KMID: 2525348
- J Korean Neurol Assoc.
- 2022 Feb;40(1):22-28.
- doi: 10.17340/jkna.2022.1.3
Background: Statin-induced myalgia is a common cause of discontinuation and a barrier that interferes with long-term treatment. The incidence of myalgia reported by previous atorvastatin trials in Korea ranged from... -
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- Adverse effects of statin therapy and their treatment
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Cheon DY, Jo SH
- KMID: 2536926
- Cardiovasc Prev Pharmacother.
- 2022 Jan;4(1):1-6.
- doi: 10.36011/cpp.2022.4.e4
Statins are one of the most widely used drugs worldwide as first-line drugs for the treatment of hyperlipidemia and the prevention and treatment of cardiovascular diseases. Most of the side... -
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- The Association between Medication Use for Dyslipidemia and Osteoporosis
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Lee H, Kim J, Rhew K
- KMID: 2524614
- Korean J Clin Pharm.
- 2021 Dec;31(4):278-284.
- doi: 10.24304/kjcp.2021.31.4.278
Background: Osteoporosis is a disease that affects the quality of life and imposes a high socioeconomic burden. Studies have reported that statins, a HMG CoA reductase inhibitor, have a positive... -
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- Statin-Induced Immune-Mediated Necrotizing Myopathy with Anti-HMGCR Antibody
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Lee J, Kim E, Kim N, Park HJ, Kim YH
- KMID: 2523958
- Korean J Neuromuscul Disord.
- 2021 Dec;13(2):64-66.
- doi: 10.46518/kjnmd.2021.13.2.64
Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (anti-HMGCR) antibody related immune-mediated necrotizing myopathy (IMNM) are usually associated with statin use. The disease has features of persistent muscle weakness and creatine kinase (CK) elevation... -
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- Statin Supply and Polydrug Use in Older Adults: A Focus on Drug Combinations that Reduce Bone Density
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Ho J, Kim B, Kim KS, Jihn CH, Kim MY, Kang DR, Park YH, Ahn J
- KMID: 2523707
- Ann Geriatr Med Res.
- 2021 Dec;25(4):269-277.
- doi: 10.4235/agmr.21.0103
Background: We investigated the comorbidities of individuals who were prescribed statins to identify the use of bone mineral density (BMD)-reducing drugs, examine polydrug use trends involving these drugs, and explore... -
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- Combination of Simvastatin and FAC Improves Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
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Yulian ED, Siregar NC, B
- KMID: 2521582
- Cancer Res Treat.
- 2021 Oct;53(4):1072-1083.
- doi: 10.4143/crt.2020.1024
Purpose The efficacy of neoadjuvant chemotherapy for locally advanced breast cancer (LABC) is limited due to drug resistance and cardiotoxic effects. Preclinical studies have shown that statin induces apoptosis and... -
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- Atherosclerotic Cardiovascular Disease Risk and Statin Prescription Status in Korean Adult Patients
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Kim JY, Rhew K
- KMID: 2520994
- Korean J Clin Pharm.
- 2021 Sep;31(3):198-204.
- doi: 10.24304/kjcp.2021.31.3.198
Background: Cardiovascular (CV) disease is known as one of the major causes of death from disease worldwide. Statin therapy plays a pivotal role in atherosclerotic cardiovascular disease (ASCVD) lowering the... -
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- Combination of Statin and Ezetimibe versus Statin Monotherapy on Cardiovascular Disease and Type 2 Diabetes Incidence among Adults with Impaired Fasting Glucose: a PropensityMatched Nationwide Cohort Study
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Lee YB, Kim B, Han K, Kim JA, Roh E, Hong Sh, Choi KM, Baik SH, Yoo HJ
- KMID: 2531865
- J Lipid Atheroscler.
- 2021 Sep;10(3):303-312.
- doi: 10.12997/jla.2021.10.3.303
Objective: We investigated the effects of statin-ezetimibe combination therapy compared with statin-only treatment on the hazard of incident type 2 diabetes (T2D), myocardial infarction (MI), and stroke among adults with... -
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- Statin Therapy and the Risk of Osteoporotic Fractures in Patients with Metabolic Syndrome: a Nested Case-Control Study
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Kim KJ, Choi J, Kim JY, Bae JH, Kim KJ, Kim HY, Yoo HJ, Seo JA, Kim NH, Choi KM, Baik SH, Kim SG, Kim NH
- KMID: 2531863
- J Lipid Atheroscler.
- 2021 Sep;10(3):322-333.
- doi: 10.12997/jla.2021.10.3.322
Objective: We aimed to investigate the association between statin use and the risk of major osteoporotic fractures in patients with metabolic syndrome (MetS). Methods: A nested case-control study was performed in... -
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- Bisphosphonate Use Does Not Impact Survival in Patients with Pancreatic Cancer: A Propensity Score Matching Analysis
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Zylberberg HM, Rustgi SD, Yang A, Aronson A, Kessel E, Amin S, Lucas AL
- KMID: 2520130
- Gut Liver.
- 2021 Sep;15(5):782-790.
- doi: 10.5009/gnl20297
Background/Aims: Bisphosphonates are increasingly recognized for their anti-neoplastic properties, which are the result of their action on the mevalonate pathway. Our primary aim was to investigate the association between bisphosphonate... -
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- Effect of pravastatin on erythrocyte membrane fatty acid contents in patients with chronic kidney disease
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Lee SM, Son YK, Kim SE, Kim YH, Park Y, An WS
- KMID: 2524385
- Kidney Res Clin Pract.
- 2021 Sep;40(3):392-400.
- doi: 10.23876/j.krcp.20.247
Background: Statin treatment has decreased the risk of cardiovascular events in patients with chronic kidney disease (CKD). Erythrocyte membrane oleic acid level is higher in patients with acute coronary syndrome.... -
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- Comparison of the Effects of Highintensity Statin Therapy with Moderate-Intensity Statin and Ezetimibe Combination Therapy on Major Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction: a Nationwide Cohort Study
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Kim K, Bang WD, Han K, Kim B, Lee JM, Chung H
- KMID: 2531866
- J Lipid Atheroscler.
- 2021 Sep;10(3):291-302.
- doi: 10.12997/jla.2021.10.3.291
Objective: We compared the effects of high-intensity statin monotherapy versus moderateintensity statin and ezetimibe combination therapy on major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI). Methods: Using... -
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