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Metabolic Syndrome in Children and Adolescents

Chung YL, Rhie YJ

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that include hypertension, altered glucose metabolism, dyslipidemia, and abdominal obesity and is strongly associated with an increased risk for diabetes and...
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The crosstalk between insulin resistance and nonalcoholic fatty liver disease/metabolic dysfunction-associated fatty liver disease: a culprit or a consequence?

Koo DJ, Lee WY

Nonalcoholic fatty liver disease (NAFLD), which has recently undergone a change in its definition and acronym to “metabolic dysfunction associated fatty liver disease (MAFLD),” is clinically significant as an increasingly...
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Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations

Kim SS, Cheong JY

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The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults

Lee JH, Park K, Lee HS, Park HK, Han JH, Ahn SB

Background/Aims: The early detection and prevention of non-alcoholic fatty liver disease (NAFLD) has been emphasized considering the burden of this disease. Both hepatic and peripheral insulin resistances are strongly associated...
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Relationship of Heart Rate Variability with Triglyceride-Glucose Index among Korean Men and Women in a Primary Care Clinic

Ryu HE, Lee SB, Jung DH, Park B

Background: Reduced heart rate variability (HRV) can be a predictor of all causes of death. Few studies have analyzed the association between HRV and the triglyceride-glucose (TyG) index in a...
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Associations between Serum Ferritin and Triglyceride Glucose Index: Using Health Examination Data at One Medical Institution’s Health Examination Center (2020)

Lee JI, Joe H, Cho YJ, Shin HS, Hong SH, Yoo BW, Oh JE, Shin KS, Son DY

Background: The overload of iron in the body is known to cause oxidative stress and inflammatory damage to cell and tissues, leading to diabetes mellitus. The relationship between serum ferritin,...
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Body fat distribution and insulin resistance among Korean middle-aged women: a Korean National Health and Nutrition Examination Survey

Lee SM, Ryu KJ, Son S, Lee YJ, Park H, Kim T

Objective To evaluate menopause-related changes in body fat distribution and their relationship with insulin resistance in middleaged Korean women. Methods We analyzed women aged 40-60 years using data from the National Health and...
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The effects of Allomyrina dichotoma larval extract on palmitate-induced insulin resistance in skeletal muscle cells

Kim K, Sim MS, Kwak MK, Jang SE, Oh YS

Purpose: Allomyrina dichotoma larvae are one of the approved edible insects with nutritional value and various functional and medicinal properties. Previously we have demonstrated that the Allomyrina dichotoma ...
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The Impact of Insulin Resistance on Hepatic Fibrosis among United States Adults with Non-Alcoholic Fatty Liver Disease: NHANES 2017 to 2018

Bae JC, Beste LA, Utzschneider KM

Background: We aimed to investigate the association of hepatic steatosis with liver fibrosis and to assess the interactive effects of hepatic steatosis and insulin resistance on liver fibrosis in a...
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Association between Relative Handgrip Strength and Insulin Resistance in Korean Elderly Men without Diabetes: Findings of the 2015 Korea National Health Nutrition Examination Survey

Joo KC, Son DH, Park JM

Background: Evidence regarding the association between handgrip strength (HGS) and insulin resistance in a non-diabetic population is scarce. This study aimed to investigate the association between relative HGS and insulin...
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Normalized Creatinine-to-Cystatin C Ratio and Risk of Diabetes in Middle-Aged and Older Adults: The China Health and Retirement Longitudinal Study

Qiu S, Cai X, Xie B, Yuan Y, Sun Z, Wu T

Background: Creatinine-to-cystatin C ratio is recently suggested to be a surrogate marker for sarcopenia. However, little is known about its association with diabetes. This study aimed to fill in this...
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Pathophysiological aspects of insulin resistance in Atrial Fibrillation: novel therapeutic approaches

Rafaqat S, Rafaqat S, Rafaqat S

Background: Insulin resistance is associated with metabolic disorders including diabetes, obesity, hypertension, and inflammation which are the risk factors for Atrial Fibrillation. Many studies have reported that type 2 diabetes...
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Iron Overload and the Risk of Diabetes in the General Population: Results of the Chinese Health and Nutrition Survey Cohort Study

Gao H, Yang J, Pan W, Yang M

Background: Recent studies have found that there are significant associations between body iron status and the development of diabetes. In the present study, we aimed to analyze the association among...
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Food Security Moderates the Relationships of Muscle Mass with Metabolic Syndrome and Insulin Resistance

Lee K

Background: This study aimed to determine whether food security moderates the relationship of skeletal muscle mass with metabolic syndrome (MetS) and insulin resistance (IR). Methods: This study analyzed the data of...
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The Impact of Psychological Insulin Resistance on Self-Care Activities in Patients with Type 2 Diabetes Mellitus Undergoing Insulin Therapy

Kim MG, Song HJ

Purpose: The purpose of this study was to identify the level of psychological insulin resistance and self-care activities and to evaluate the factors affecting self-care activities in patients with type...
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The Role of T Cells in Obesity-Associated Inflammation and Metabolic Disease

Park CS, Shastri N

Chronic inflammation plays a critical role in the development of obesity-associated metabolic disorders such as insulin resistance. Obesity alters the microenvironment of adipose tissue and the intestines from anti-inflammatory to...
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The protective effects of Aster yomena (Kitam.) Honda on high-fat diet-induced obese C57BL/6J mice

Kim MJ, Kim JH, Lee S, Kim B, Kim HY

BACKGROUND/OBJECTIVES: Aster yomena (Kitam.) Honda (AY) has remarkable bioactivities, such as antioxidant, anti-inflammation, and anti-cancer activities. On the other hand, the effects of AY against obesity-induced insulin resistance have not...
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Insulin Resistance: From Mechanisms to Therapeutic Strategies

Lee SH, Park SY, Choi CS

Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological...
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Four-year changes in central fatness, risk of diabetes, and metabolic control in older adults: a cohort study with mediation analysis

Cai X, Luo D, Liu S, Li R, Lu Y, Li M, Qiu S

Background/Aims: Older adults are vulnerable to central obesity, while the association of changes in central fatness with risk of diabetes and metabolic control has not been investigated among this particular...
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Effect of obesity and metabolic health on urolithiasis: A nationwide population-based study

Choi C, Kim JK, Han K, Lee YG, Han JH

Purpose: To investigate the risk of symptomatic urolithiasis requiring surgical treatment according to obesity and metabolic health status using a nationwide dataset of the Korean population. Materials and Methods: Of the...
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