J Korean Neurosurg Soc.  2003 Jan;33(1):1-12.

Stem Cells and Neurosurgery

Affiliations
  • 1Department of Neurosurgery, Daejeon St. Mary's Hospital, The Catholic University College of Medicine, Daejeon, Korea. leeilwoo@djwungmo.com

Abstract

Stem cells are defined as cells that have the ability of self-renewal and potentiality to differentiate into multilineage cells. Recently those stem cells have been isolated from the embryos, fetuses, and even in the adult tissues of the mammalians including humans. Stem cells have great potential as therapeutic tools for various disorders resulted from disruption of cellular function or destruction of body tissues, including heart diseases, diabetes, burns, strokes, spinal cord injuries and many other neurodegenerative diseases. Especially, the central nervous system, unlike many other tissues, has a limited capacity of self repair, the cell transplantation with neuronal stem cells can be the most promising treatment for the neurodegenerative diseases or the central nervous system injuries. The author reviewed the current research trends related with stem cells and discussed the feasibilities and the limitations of the cell therapy for several neurological disorders by using various kinds of stem cells. The roles of neurosurgeons in this field are also discussed.

Keyword

Stem cells; Cell therapy; Neurosurgery; Neurological disorders

MeSH Terms

Adult
Burns
Cell Transplantation
Cell- and Tissue-Based Therapy
Central Nervous System
Embryonic Structures
Fetus
Heart Diseases
Humans
Nervous System Diseases
Neurodegenerative Diseases
Neurons
Neurosurgery*
Spinal Cord Injuries
Stem Cells*
Stroke
Transplants
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