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Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats

Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK

Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma...
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Real world effectiveness and safety of pegylated liposomal doxorubicin in platinum-sensitive recurrent ovarian, fallopian, or primary peritoneal cancer: a Korean multicenter retrospective cohort study

Park SJ, Kim J, Kim HS, Lee JW, Chang HK, Lee KH, Kim DY, Kim S, Chang SJ, Han SS, Park SY, Shim SH

OBJECTIVE: To evaluate the effectiveness and safety of the combination of pegylated liposomal doxorubicin with carboplatin (CD) compared with those of carboplatin and paclitaxel (CP) for platinum-sensitive recurrent ovarian, fallopian,...
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Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders

Choi S, Kim SW, Jeon HR, Lee JS, Kim DY, Lee JW

Robots are being used to assist the recovery of walking ability for patients with neurologic disorders. This study aimed to evaluate the feasibility and functional improvement of training with robot-assisted...
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Disease-Specific Mortality and Prevalence Trends in Korea, 2002–2015

Shin Y, Park B, Lee HA, Park B, Han H, Choi EJ, Kim NE, Park H

BACKGROUND: Evaluation of mortality and prevalence trends is important for health planning and priority decision-making in health policy. This study was performed to examine disease-specific mortality and prevalence trends for...
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MR Neurography: Current Several Issues for Novice Radiologists

Ha DH

Magnetic resonance neurography (MRN) has been increasingly used in recent years for the assessment of peripheral neuropathies. Fat suppression T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) have typically been used...
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Immune-Mediated Peripheral Neuropathy in Patients with Diffuse Panbronchiolitis

Kang YR, Nam TS, Lee KH, Kim S, Park HJ, Lee SJ, Lee SH, Kim BC

No abstract available.
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Diabetic Peripheral Neuropathy as a Risk Factor for Sarcopenia

Oh TJ, Song Y, Moon JH, Choi SH, Jang HC

BACKGROUND: Diabetic peripheral neuropathy (DPN) is prevalent in patients with type 2 diabetes, and its prevalence increases with age. A previous study demonstrated the association between DPN and muscle dysfunction;...
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Full mouth rehabilitation for a Parkinson's diseases patient with chronic periodontitis: a case report

Koh ES, Kim JJ, Baik J, Cha HS, Lee JH

Parkinson's disease is a neurological disorder characterized by tremor, bradykinesia, akinesia, postural instability, and muscular rigidity, which is caused by the depletion of neurotransmitters such as dopamine. Cooperative dental treatment...
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Meta-analysis on the Efficacy of Glutamate Receptor Antagonists for Acute Migraine Treatment

Kim S, Baek IH

BACKGROUND: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to...
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White matter hyperintensities in migraine: a review

Lee MJ, Moon S, Chung CS

Migraine is a neurological disorder characterized by recurrent spells of headache accompanied by brain symptoms such as nausea, vomiting, photophobia, and phonophobia. White matter hyperintensity (WMH) is the most frequent...
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Recurrent Optic Neuritis and Acute Encephalopathy with Myelin Oligodendrocyte Glycoprotein Antibodies in a Korean Child

Hwang JE, Kim SH, Park S

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases are reported to have distinct pathogenic mechanisms, clinical courses, and therapeutic implications in comparison to other acquired demyelinating syndromes. Here, we report the case...
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Diagnostic Usefulness of Digital Infrared Thermal Image in Carpal Tunnel Syndrome

Park J, Lee JW, Lee SE, Kim BH, Park D

OBJECTIVE: The purpose of this study is to evaluate the usefulness of infrared thermography in patients with carpal tunnel syndrome by comparing with electrodiagnostic and ultrasonographic findings. METHOD: From January 2014...
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Perspectives in TSPO PET Imaging for Neurologic Diseases

Song YS

The translocator protein (18 kDa) (TSPO) is a mitochondrial transmembrane protein, which has brought attention as a neuroinflammatory biomarker. Positron emission tomography (PET) imaging studies have been done for several...
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Oxaliplatin-induced Peripheral Neuropathy, Symptoms, Distress and Quality of Life among Korean Patients with Gastrointestinal Cancer

Jung HJ, Ahn SJ, Yang YR, Kim KA, Shin SJ, Jung MK, Chu SH

PURPOSE: This study was conducted to identify the level of oxaliplatin-induced peripheral neuropathy (OIPN), symptoms, distress, and quality of life (QoL) in gastrointestinal (GI) cancer patients and to identify the...
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Benefits of hesperidin in central nervous system disorders: a review

Kim J, Wie MB, Ahn M, Tanaka A, Matsuda H, Shin T

Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy individuals. Hesperidin, which is an abundant...
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Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner

Gim E, Shim DW, Hwang I, Shin OS, Yu JW

Zika virus (ZIKV) is a mosquito-borne flavivirus associated with severe neurological disorders including Guillain-Barré syndrome and microcephaly. The host innate immune responses against ZIKV infection are essential for protection; however,...
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Cutaneous squamous cell carcinoma: High risk factors, staging and management

Park HJ

Cutaneous squamous cell carconoma(cSCC) is a malignant neoplasm derived from suprabasal epidermal keratinocytes, which is one of the nonmelanoma skin cancers that represent the most common malignancies in humans. Although...
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Pediatric Home Mechanical Ventilation in Korea: the Present Situation and Future Strategy

Park M, Jang H, Sol IS, Kim SY, Kim YS, Kim YH, Sohn MH, Kim KW

BACKGROUND: The number of children using home mechanical ventilation (HMV) has increased markedly in Europe and North America, but little is known about the situation in Korea. We described the...
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Tissue-Clearing Technique and Cutaneous Nerve Biopsies: Quantification of the Intraepidermal Nerve-Fiber Density Using Active Clarity Technique-Pressure Related Efficient and Stable Transfer of Macromolecules Into Organs

Kim DH, Lee SJ, Lee E, Hong JH, Seo SH, Ahn HH, Kim BJ, Sun W, Rhyu IJ

BACKGROUND AND PURPOSE: Cutaneous nerve biopsies based on two-dimensional analysis have been regarded as a creditable assessment tool for diagnosing peripheral neuropathies. However, advancements in methodological imaging are required for...
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Prediction of Chemotherapy-Induced Peripheral Neuropathy in Patients with Lymphoma and Myeloma: the Roles of Brain-Derived Neurotropic Factor Protein Levels and A Gene Polymorphism

Azoulay D, Giryes S, Nasser R, Sharon R, Horowitz N

BACKGROUND AND PURPOSE: Brain-derived neurotrophic factor (BDNF) is a neuronal growth factor that plays an essential role in the maintenance of the nervous system. We have evaluated the peripheral blood...
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