- Corrigendum to: Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion
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Cho KO, Kim SK, Kim SY
- KMID: 2534530
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):557-557.
- doi: 10.4196/kjpp.2022.26.6.557
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- Antitumor effects of valdecoxib on hypopharyngeal squamous carcinoma cells
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Trang NTK, Yoo H
- KMID: 2534520
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):439-446.
- doi: 10.4196/kjpp.2022.26.6.439
The antitumoral effects of valdecoxib (Val), an United States Food and Drug Administration-approved anti-inflammatory drug that was withdrawn due to the side effects of increased risk of cardiovascular adverse events,... -
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- Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells
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Chang JW, Kim S, Lee EY, Leem CH, Kim SH, Park CS
- KMID: 2534524
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):479-499.
- doi: 10.4196/kjpp.2022.26.6.479
The lack of a clonal renin-secreting cell line has greatly hindered the investigation of the regulatory mechanisms of renin secretion at the cellular, biochemical, and molecular levels. In the present... -
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- The physiological and pharmacological roles of prostaglandins in hair growth
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Shin DW
- KMID: 2534517
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):405-413.
- doi: 10.4196/kjpp.2022.26.6.405
Hair loss is a common status found among people of all ages. Since the role of hair is much more related to culture and individual identity, hair loss can have... -
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- The WNT/Ca2+ pathway promotes atrial natriuretic peptide secretion by activating protein kinase C/transforming growth factor-β activated kinase 1/activating transcription factor 2 signaling in isolated beating rat atria
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Li Zy, Liu Y, Han Zn, Li X, Wang Yy, Cui X, Zhang Y
- KMID: 2534523
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):469-478.
- doi: 10.4196/kjpp.2022.26.6.469
WNT signaling plays an important role in cardiac development, but abnormal activity is often associated with cardiac hypertrophy, myocardial infarction, remodeling, and heart failure. The effect of WNT signaling on... -
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- Group 1 metabotropic glutamate receptor 5 is involved in synaptically-induced Ca2+ -spikes and cell death in cultured rat hippocampal neurons
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Yang JS, Jeon S, Jang HJ, Yoon SH
- KMID: 2534528
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):531-540.
- doi: 10.4196/kjpp.2022.26.6.531
Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved... -
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- Thermotherapy as an alternative to exercise for metabolic health in obese postmenopausal women: focus on circulating irisin level
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Lee SJ, Kim TW, Park TH, Lee IH, Jang EC, Kwon SC, Lee HJ, Choi JH, Lee JB
- KMID: 2534525
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):501-509.
- doi: 10.4196/kjpp.2022.26.6.501
Irisin is a myokine caused by exercise that improves insulin resistance and weight loss. However, under unfavorable conditions such as air pollution, and during the pandemic, outdoor activities are uncomfortable.... -
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- Lactate promotes vascular smooth muscle cell switch to a synthetic phenotype by inhibiting miR-23b expression
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Hu Y, Zhang C, Fan Y, Zhang Y, Wang Y, Wang C
- KMID: 2534527
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):519-530.
- doi: 10.4196/kjpp.2022.26.6.519
Recent research indicates that lactate promotes the switching of vascular smooth muscle cells (VSMCs) to a synthetic phenotype, which has been implicated in various vascular diseases. This study aimed to... -
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- Myricetin prevents sleep deprivation-induced cognitive impairment and neuroinflammation in rat brain via regulation of brain-derived neurotropic factor
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Sur B, Lee B
- KMID: 2534518
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):415-425.
- doi: 10.4196/kjpp.2022.26.6.415
Memory formation in the hippocampus is formed and maintained by circadian clock genes during sleep. Sleep deprivation (SD) can lead to memory impairment and neuroinflammation, and there remains no effective... -
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- Neogambogic acid relieves myocardial injury induced by sepsis via p38 MAPK/NF-κB pathway
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Fu W, Fang X, Wu L, Hu W, Yang T
- KMID: 2534526
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):511-518.
- doi: 10.4196/kjpp.2022.26.6.511
Sepsis-associated myocardial injury, an invertible myocardial depression, is a common complication of sepsis. Neogambogic acid is an active compound in garcinia and exerts anthelmintic, anti-inflammatory, and detoxification properties. The role of... -
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- Arctigenin induces caspase-dependent apoptosis in FaDu human pharyngeal carcinoma cells
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Kang KR, Kim JS, Lim H, Seo JY, Park JH, Chun HS, Yu SK, Kim HJ, Kim CS, Kim DK
- KMID: 2534521
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):447-456.
- doi: 10.4196/kjpp.2022.26.6.447
The present study was carried out to investigate the effect of Arctigenin on cell growth and the mechanism of cell death elicited by Arctigenin were examined in FaDu human pharyngeal... -
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- The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy
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Zhao W, He C, Jiang J, Zhao Z, Yuan H, Wang F, Shen B
- KMID: 2534519
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):427-438.
- doi: 10.4196/kjpp.2022.26.6.427
Pyroptosis, a form of cell death associated with inflammation, is known to be involved in diabetic nephropathy (DN), and discoid domain receptor 1 (DDR1), an inflammatory regulatory protein, is reported... -
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- Involvement of adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 in diallyl trisulfide-induced cytotoxicity in hepatocellular carcinoma cells
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Guan F, Ding Y, He Y, Li L, Yang X, Wang C, Hu M
- KMID: 2534522
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):457-468.
- doi: 10.4196/kjpp.2022.26.6.457
It has been demonstrated that APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) is involved in the regulation of several growth-related signaling pathways and thus closely... -
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- Gaseous signal molecule SO2 regulates autophagy through PI3K/ AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes
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Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
- KMID: 2534529
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):541-556.
- doi: 10.4196/kjpp.2022.26.6.541
Myocardial fibrosis is a key link in the occurrence and development of diabetic cardiomyopathy. Its etiology is complex, and the effect of drugs is not good. Cardiomyocyte apoptosis is an important... -
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