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Design of precise third-line therapy for gastric cancer: target or chemotherpy?

Cho JY

No abstract available.
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Gastric Metastasis from Breast Cancer

Yoon SY, Shim KN

No abstract available.
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Cisplatin-Induced Encephalopathy With Status Epilepticus

Kim NY, Bae SY, Lee SJ

  • KMID: 2343481
  • J Korean Neurol Assoc.
  • 2013 May;31(2):122-124.
A 75-year old man with esophageal cancer presented with mental status change and seizures. He was under cisplatinand developed several times of generalized tonic-clonic seizures. The EEG (electroencephalography) showed triphasic...
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A Case of Onycholysis with Subungual Suppuration Secondary to Paclitaxel

Jung JY, Woo SM, Min SU, Suh DH

  • KMID: 2302122
  • Korean J Dermatol.
  • 2008 Feb;46(2):278-280.
Paclitaxel is one of the taxoid-antineoplastic agents. These agents are used in the treatment of breast, lung and ovary cancer. Nail changes due to treatment with the taxanes (mainly docetaxel)...
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The evidence for adjuvant taxanes in early breast cancer

Basi S, Mackey JR

Adjuvant chemotherapy plays an important role in improving disease free and overall survival in women with high-risk early stage breast cancer. While more than seventy thousand women have enrolled in...
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Chemotherapy of Head and Neck Cancer

Yeo CK

Head and neck cancers comprise a heterogenous group of cancers that require a multidisciplinary approach. Surgery, radiation therapy, chemotherapy and, more recently, target therapy are often employed in various combinations...
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Recent Advances in Chemotherapy of Gastric Cancer

Park SH, Lee SI

  • KMID: 2264289
  • Korean J Med.
  • 2012 Apr;82(4):417-426.
Surgery is the best and the only treatment modality for cure if a patient has resectable gastric cancer. The outcome can be improved by a strategy of perioperative (neoadjuvant or...
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Secondary Prophylaxis of Docetaxel Induced Diarrhea with Loperamide: Case Report

Lee HY, Lee YH, Kim MJ, Kim HK

Diarrhea is a common adverse event of docetaxel with 20%-40% of incidence and severe diarrhea occurs in 5%-6%. Several treatment guidelines for chemotherapy induced diarrhea (CID) exist, however the prophylaxis...
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Prediction of Acquired Taxane Resistance Using a Personalized Pathway-Based Machine Learning Method

Kim YR, Kim D, Kim SY

PURPOSE: This study was conducted to develop and validate an individualized prediction model for automated detection of acquired taxane resistance (ATR). MATERIALS AND METHODS: Penalized regression, combinedwith an individualized pathway score...
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Docetaxel-induced Severe Fluid Retention in a Breast Cancer Patient: A Case Report

Jeon YS, Kang SH, Lee SJ

Among many adverse effects of docetaxel, fluid retention is a well recognized, cumulative side effect, but severe fluid retention is rare. We report here on a case of docetaxel-induced severe...
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Microtubule-Associated Protein Tau, alpha-Tubulin and betaIII-Tubulin Expression in Breast Cancer

Im S, Yoo C, Jung JH, Jeon YW, Suh YJ, Lee YS, Choi HJ

  • KMID: 2012154
  • Korean J Pathol.
  • 2013 Dec;47(6):534-540.
BACKGROUND: The microtubule-associated protein Tau binds to both inner and outer surfaces of microtubules, leading to tubulin assembly and microtubule stabilization. The aim of this study was to evaluate the...
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Comparison of Gefitinib versus Docetaxel in Patients with Pre-Treated Non-Small Cell Lung Cancer (NSCLC)

Hirsh V

More effective treatments in first, second, and third-line of metastatic non-small cell lung cancer (NSCLC) enable patients to live longer, with a better quality of life (QOL). Especially epidermal growth...
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Photosensitivity Reactions to Vandetanib: Redevelopment after Sequential Treatment with Docetaxel

Son YM, Roh JY, Cho EK, Lee JR

Vandetanib (ZD6474, Zactima(TM)) is a novel, orally available inhibitor of different intracellular signaling pathways involved in tumor growth, progression, and angiogenesis, including vascular endothelial growth factor receptor-2, epidermal growth factor...
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Adjuvant Chemotherapy for Breast Cancer

Paik NS, Noh WC

Breast cancer is one of the most common malignancies of lethal potential for women in the developed world. Over the past two decades, we have witnessed dramatic advances in the...
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A case of unrecognized pregnancy during chemotherapy in non-small cell lung cancer patient

Park JY, Park JW, Lee DO, Park CW, Park JS, Jun JK, Syn HC

Most chemotherapeutic drugs are known to possess significant teratogenic effects. Although several agents have been proven to be safe for the fetus after organogenesis period, there is limited information on...
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Esophageal Cancer with Left Main Bronchus Obstruction

Kang SJ, Oh IJ, Kim KS, Kim YC

A 66-year-old man with recurrent esophageal cancer was admitted to our health care facility for evaluation of resting dyspnea. He had undergone an esophagectomy with cervical esophagogastrostomy in May 2007...
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Docetaxel-Induced Fatal Interstitial Pneumonitis in a Patient with Castration-Resistant Prostate Cancer

Min BD, Kang HW, Kim WT, Kim YJ, Yun SJ, Lee SC, Kim WJ

  • KMID: 2315589
  • Korean J Urol.
  • 2012 May;53(5):371-374.
A 69-year-old man with castration-resistant prostate cancer (CRPC) received docetaxel and a corticosteroid. After the third cycle of docetaxel administration, he presented with dyspnea, cough, sputum, and fever of 39.2degrees...
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Complete biologic response to taxane based chemotherapy confirmed by [18F]FDG PET/CT and surgery in a cancer of unknown primary site

Hwang JE, Yoon JY, Bae WK, Shim HJ, Chung IJ

Cancers of an unknown primary site are heterogenous with respect to their clinical and pathologic features. They are generally very aggressive, but specific favorable subsets have a better prognosis. For...
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Chemotherapy of Advanced Gastric Cancer

Jung JT

Gastric cancer is a common malignancy worldwide with a high mortality rate. In advanced gastric cancer, combination chemotherapy improves overall survival compared with best supportive care alone. However, there is...
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Symptom and Interference of Activities of Daily Living of Chemotherapy-Induced Peripheral Neuropathy in Patients Receiving Taxanes and Platinums

Kim JH, Lee KM, Jeon MJ, Seol ME, Lee SH, Park J

PURPOSE: The purpose of this study was to identify the symptoms and interference of activities of daily living (ADL) of chemotherapy induced peripheral neuropathy (CIPN) in patients receiving taxane and...
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