- Report of Two Cases of Hypomelanosis of Vitiligo Type Probably due to Benoquin
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Kim MS, Hong JJ, Kook HI
- KMID: 1664470
- Korean J Dermatol.
- 1974 Dec;12(4):305-308.
Two cases of vitiligo-type hypomelanosis followed by the local application of Benoquin ointment for the treatment for the treatment of melasma are reported. These two cases of hypomelanosis are unwanted... -
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- A Case of Melanotrichoblastoma
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Shim HS, Seo JW, Seo JK, Lee SK
- KMID: 1472461
- Korean J Dermatol.
- 2009 Jan;47(1):80-83.
Melanotrichoblastoma is a variant of pigmented trichoblastoma that shows highly pigmented epithelial lobules and differentiation toward the hair bulb. Histologically, the tumor presents features of trichoblastoma, and the histological findings... -
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- Sequence Analysis of the Human Tyrosinase Gene in Korean
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Park KC, Kim KH
- KMID: 2361410
- Ann Dermatol.
- 1995 Jan;7(1):34-38.
- doi: 10.5021/ad.1995.7.1.34
BACKGOUND: Because heterogeneity of the human tyrosinase gene has been reported, it is of vital significance to know the correct nucleotide sequence of tyrosinase in Koreans in order to study... -
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- A Simple Assay Method for Melanosome Transfer
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Choi HR, Park SH, Choi JW, Kim DS, Park KC
- KMID: 2156865
- Ann Dermatol.
- 2012 Feb;24(1):90-93.
- doi: 10.5021/ad.2012.24.1.90
Pigmentation is induced by production of melanin in specialized organelles termed melanosomes and by transfer of these organelles from melanocytes to surrounding keratinocytes. The chemical basis of melanogenesis is relatively... -
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- A Case of Oculocutaneous Albinism 1A Accompanying with Tyrosinase Mutation
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Kwon JI, Ha JS, Lee KS, Cho JW
- KMID: 2302403
- Korean J Dermatol.
- 2012 Nov;50(11):987-990.
Oculocutaneous albinism (OCA) is a heterogeneous autosomal recessive disorder with reduction or complete absence of melanin in the skin, hair, eyes and combined with eye disorder, such as nystagmus and... -
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- Two Cases of Oculocutaneous Albinism with Congenital Nystagmus
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Han GC, Lee JH, Paik HJ
- KMID: 2074519
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Jul;47(7):683-691.
Albinism is a hereditary disease caused by the defect of tyrosinase that converts tyrosine to dihydroxyphenylalanine (DOPA). `Oculocutaneous albinism' is classified as hypopigmentation of skin, hair and eyes, but incidences... -
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- Topical Hypopigmenting Agents for Pigmentary Disorders and Their Mechanisms of Action
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Kim H, Choi HR, Kim DS, Park KC
- KMID: 2156847
- Ann Dermatol.
- 2012 Feb;24(1):1-6.
- doi: 10.5021/ad.2012.24.1.1
Melanin is produced in melanocytes and stored in melanosomes. In spite of its beneficial sun-protective effect, abnormal accumulation of melanin results in esthetic problems. Hydroquinone, competing with tyrosine, is a... -
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- Skin Whitening Effects of Sanguisorba officinalis and Stichopus japonicus
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Lee MO, Oh HG, Park SH, Lee HA, Sul JD, Song J, Kim O
- KMID: 2312057
- Lab Anim Res.
- 2010 Jun;26(2):127-132.
- doi: 10.5625/lar.2010.26.2.127
This study is aimed to evaluate skin whitening effects of Sanguisorba officinalis and Stichopus japonicus for cosmeceutical ingredients. The extract of Stichopus japonicus showed 61.78% inhibition of tyrosinase activity, and... -
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- The Features of Tyrosinase Expressions in Pigmentary Disorders Using TTA
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Lee YK, Kim YH, Kim KH
- KMID: 2302073
- Korean J Dermatol.
- 2008 Mar;46(3):325-333.
BACKGROUND: Tyrosinase is the critical enzyme in melanin synthesis. DOPA staining has been used as a standard assay for detecting tyrosinase activity, but it exhibits several limitations. Tyramide based tyrosinase... -
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- Antioxidative Activity and Anti-melanogenic Effect of the Extract from the Leaves of Robinia Pseudo-acacia L
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Chung JS, Jin GH, Park YK
- KMID: 2359718
- Ann Dermatol.
- 1999 Jul;11(3):142-146.
- doi: 10.5021/ad.1999.11.3.142
BACKGROUND: Plant extracts have been widely used as important therapeutic drugs for many centuries all over the world. There have been many reports that natural products have various kinds of... -
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- Codon Usage Patterns of Tyrosinase Genes in Clonorchis sinensis
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Bae YA
- KMID: 2379420
- Korean J Parasitol.
- 2017 Apr;55(2):175-183.
- doi: 10.3347/kjp.2017.55.2.175
Codon usage bias (CUB) is a unique property of genomes and has contributed to the better understanding of the molecular features and the evolution processes of particular gene. In this... -
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- Immunohistochemical Study of Malignant Melanoma with HMB-45, Antibodies against S100 Protein, Melan-A, and Tyrosinase
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Park JH, Lee DY, Lee ES
- KMID: 2302610
- Korean J Dermatol.
- 2005 Jun;43(6):756-761.
BACKGROUND: Immunohistochemical confirmation is needed to correctly diagnose malignant melanoma, due to its heterogeneous histological appearance. OBJECTIVE: In the diagnosis of malignant melanoma, we evaluated the usefulness of recently introduced... -
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- The Effect of Placental Extract on the Expression of Tyrosinase, TRP-1 and TRP-2 in SK30 Melanoma Cells
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Kim HJ, Lee JW, Kim YI, Lee MH
- KMID: 1977854
- Korean J Dermatol.
- 2003 Dec;41(12):1612-1618.
Placental extract is a reservoir of a large number of bioactive molecules. It has been used in skin care cosmetics and soap, it is expected to have skin whitening effect.... -
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- A Case of Oculocutaneous Albinism Induced by Tyrosinase Mutation
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Kim WJ, Kim SH, Jung DS, Ko HC, Kim MB, Kwon KS
- KMID: 2247750
- Korean J Dermatol.
- 2009 Nov;47(11):1291-1295.
Oculocutaneous albinism (OCA) is a group of inherited disorders of the melanin synthesizing system, and these are characterized by hypopigmentation of the hair, skin and eyes, with a normal number... -
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- Whitening Effects of Marine Pseudomonas Extract
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Kang HY, Yoon TJ, Lee GJ
- KMID: 2156654
- Ann Dermatol.
- 2011 May;23(2):144-149.
- doi: 10.5021/ad.2011.23.2.144
BACKGROUND: Bacteria associated with marine invertebrates are a rich source of bioactive metabolites. OBJECTIVE: The effects of marine bacteria extracts on pigmentation were investigated to find novel whitening agents. METHODS: The marine... -
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- Anti-melanogenic effects of black, green, and white tea extracts on immortalized melanocytes
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Kim YC, Choi SY, Park EY
- KMID: 2164521
- J Vet Sci.
- 2015 Jun;16(2):135-143.
- doi: 10.4142/jvs.2015.16.2.135
Tea contains polyphenols and is one of the most popular beverages consumed worldwide. Because most tyrosinase inhibitors that regulate melanogenesis are phenol/catechol derivatives, this study investigated the inhibitory effects of... -
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- Inhibition of Melanogenesis by Abietatriene from Vitex Trifolia Leaf Oil
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Lee HG, Kim TY, Jeon JH, Lee SH, Hong YK, Jin MH
- KMID: 2366692
- Nat Prod Sci.
- 2016 Dec;22(4):252-258.
- doi: 10.20307/nps.2016.22.4.252
Vitex trifolia L. has been used traditionally to treat various illnesses, such as inflammation, headache, migraine, and gastrointestinal infections. We analyzed and evaluated the composition of V. trifolia leaf oil.... -
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- Primary Malignant Melanoma of the Breast: A Report of Two Cases
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Koh J, Lee J, Jung SY, Kang HS, Yun T, Kwon Y
- KMID: 2465451
- J Pathol Transl Med.
- 2019 Mar;53(2):119-124.
- doi: 10.4132/jptm.2018.10.18
Primary malignant melanoma of the breast (PMMB) is a rare tumor with only a few case reports available in the literature. We report two cases of PMMB, one derived from... -
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- Inhibitory and Eliminating Effects of Yeast-extracted Melanoston on Pigmentation and Preexisting Pigmentation, Respectively
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Kim JS, Park KT, Ahn YS, Yu HJ
- KMID: 1639675
- Korean J Dermatol.
- 2006 Apr;44(4):391-398.
BACKGROUND: Melanoston is a new melanogenesis inhibitor isolated from yeast. However, little is known about the mechanism of this agent in melanogenesis and also its clinical effectiveness on hyperpigmented lesions. OBJECTIVE:... -
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- Effect of L - tyrosine on Proliferation and Melanization in Cultured Normal Human Melanocytes
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Lee MH, Kim JH, Park JK, Haw CR
- KMID: 2230704
- Korean J Dermatol.
- 1996 Feb;34(1):25-30.
BACKGROUND: The biosynthesis of melanin is initiated by the enzymatic oxidation of L-tyrosine to L-dopa by tyrosinase. Some precursors of melanin are cytotoxic, and melanoma cells are killed as a... -
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