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Acute gastrointestinal dilation in laboratory rhesus monkeys in the Korea National Primate Research Center

Kim KM, Lee SR, Chang KS, Lee YH, Kim SW, Jung KJ, Lee Y, Kim D, Chang KT

Acute gastrointestinal dilation is a medical condition in which the stomach and intestine become overstretched by excessive gas content. In laboratory monkeys, cases of bloating involving gastrointestinal dilation are rarely...
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Evaluating the effects of pentoxifylline administration on experimental pressure sores in rats by biomechanical examinations

Velaei K, Bayat M, Torkman G, Rezaie F, Amini A, Noruzian M, Tavassol A, Bayat M

This study used a biomechanical test to evaluate the effects of pentoxifylline administration on the wound healing process of an experimental pressure sore induced in rats. Under general anesthesia and...
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Development of a type II diabetic mellitus animal model using Micropig(R)

Lee MS, Song KD, Yang HJ, Solis CD, Kim SH, Lee WK

Diabetes, which has shown an explosive increase in terms of its incidence, is regarded as a serious disease that must be overcome for the sake of human life. Among animal...
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Gingko biloba extract (EGb 761) attenuates ischemic brain injury-induced reduction in Ca2+ sensor protein hippocalcin

Koh PO

Gingko biloba extract 761 (EGb 761) protects neuronal cells from ischemic brain injury via a number of neuroprotective mechanisms. Hippocalcin is a calcium sensor protein that regulates intracellular calcium concentrations...
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Anticoccidial effects of Galla rhois extract on Eimeria tenella-infected chicken

Lee HA, Hong S, Chung YH, Song KD, Kim O

Anticoccidial effects of Galla rhois (GR) extract were evaluated in chickens after oral infection with Eimeria tenella. This study was performed using 3-day-old chickens (n=30). The animals were divided into...
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Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats

Kim JE, Hwang IS, Choi SI, Lee HR, Lee YJ, Goo JS, Lee HS, Son HJ, Jang MJ, Lee SH, Kang BC, Hwang DY

Liriope platyphylla is a medical herb that has long been used in Korea and China to treat cough, sputum, neurodegenerative disorders, obesity, and diabetes. The aims of this study were...
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Prophylactic effects of swimming exercise on autophagy-induced muscle atrophy in diabetic rats

Lee Y, Kim JH, Hong Y, Lee SR, Chang KT, Hong Y

Diabetes decreases skeletal muscle mass and induces atrophy. However, the mechanisms by which hyperglycemia and insulin deficiency modify muscle mass are not well defined. In this study, we evaluated the...
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Comparison of alpha-synuclein immunoreactivity in the spinal cord between the adult and aged beagle dog

Ahn JH, Choi JH, Park JH, Yan BC, Kim IH, Lee JC, Lee DH, Kim JS, Shin HC, Won MH

Alpha-synuclein (alpha-syn) is a presynaptic protein that is richly expressed in the central and peripheral nervous systems of mammals, and it is related to the pathogenesis of Parkinson's disease and...
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Effects of Red Liriope platyphylla on NGF secretion ability, NGF receptor signaling pathway and gamma-secretase components in NSE/hAPPsw transgenic mice expressing Alzheimer's Disease

Choi SI, Goo JS, Kim JE, Hwang IS, Lee HR, Lee YJ, Son HJ, Lee HS, Lee JS, Hwang DY

Liriope platyphylla (LP) has long been regarded as a curative herb for the treatment of diabetes, asthma, and neurodegenerative disorders. To examine the therapeutic effects of Red LP (RLP) manufactured...
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Heavy metal concentrations in hair of newly imported China-origin rhesus macaques (Macaca mulatta)

Lee JI, Jung WY, Lee G, Kim MS, Kim YS, Park CG, Kim SJ

Macaque monkeys are good sentinel to humans for environmental pollutions because their similarities in genetic and physiological characteristics. So, their reference values about exposures to heavy metals are required for...
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