Lab Anim Res.  2012 Sep;28(3):193-197. 10.5625/lar.2012.28.3.193.

Anticoccidial effects of Galla rhois extract on Eimeria tenella-infected chicken

  • 1Korean Medicine (KM)-Based Herbal Drug Research Group, Korea Institute of Oriental Medicine, Dajeon, Korea.
  • 2Center for Animal Resources Development, Wonkwang University, Iksan, Korea.
  • 3Institute of Animal Experiment & Efficacy Evaluation, Wonkwang University, Iksan, Korea.
  • 4Department of Companion Animal and Animal Resources Science, Joongbu University, Geumsan, Korea.
  • 5Center for Agricultural Biomaterials, Seoul National University, Seoul, Korea.
  • 6Digestive Disease Research Institute, Wonkwang University, Iksan, Korea.


Anticoccidial effects of Galla rhois (GR) extract were evaluated in chickens after oral infection with Eimeria tenella. This study was performed using 3-day-old chickens (n=30). The animals were divided into 3 groups as follows: GR 0.5%/infected (n=10), untreated/infected (n=10), and non-infected control (n=10). The chickens were fed a standard diet supplemented with or without GR for 1 week before infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of GR on E. tenella infection were assessed by 2 parameters, number of fecal oocysts and body weight gain, and the results of the polymerase chain reaction (PCR). The GR-fed chickens produced significantly lower number of fecal oocysts (P<0.05) than the E. tenella-infected chickens who were fed the standard diet. In addition, GR-based diet improved the loss of body weight caused by E. tenella infection. Positive findings of PCR were identified by distinct bands in the samples of E. tenella-inoculated chickens. However, PCR analysis revealed no E. tenella oocysts in the feces of GR-fed chickens. Our data showed that GR extracts had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of novel anticoccidial drugs.


Anticoccidial activity; coccidiosis; eimeria; eimeria tenella; galla rhois
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