Lab Anim Res.  2012 Sep;28(3):193-197. 10.5625/lar.2012.28.3.193.

Anticoccidial effects of Galla rhois extract on Eimeria tenella-infected chicken

Affiliations
  • 1Korean Medicine (KM)-Based Herbal Drug Research Group, Korea Institute of Oriental Medicine, Dajeon, Korea.
  • 2Center for Animal Resources Development, Wonkwang University, Iksan, Korea. kimoj@wku.ac.kr
  • 3Institute of Animal Experiment & Efficacy Evaluation, Wonkwang University, Iksan, Korea.
  • 4Department of Companion Animal and Animal Resources Science, Joongbu University, Geumsan, Korea.
  • 5Center for Agricultural Biomaterials, Seoul National University, Seoul, Korea.
  • 6Digestive Disease Research Institute, Wonkwang University, Iksan, Korea.

Abstract

Anticoccidial effects of Galla rhois (GR) extract were evaluated in chickens after oral infection with Eimeria tenella. This study was performed using 3-day-old chickens (n=30). The animals were divided into 3 groups as follows: GR 0.5%/infected (n=10), untreated/infected (n=10), and non-infected control (n=10). The chickens were fed a standard diet supplemented with or without GR for 1 week before infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of GR on E. tenella infection were assessed by 2 parameters, number of fecal oocysts and body weight gain, and the results of the polymerase chain reaction (PCR). The GR-fed chickens produced significantly lower number of fecal oocysts (P<0.05) than the E. tenella-infected chickens who were fed the standard diet. In addition, GR-based diet improved the loss of body weight caused by E. tenella infection. Positive findings of PCR were identified by distinct bands in the samples of E. tenella-inoculated chickens. However, PCR analysis revealed no E. tenella oocysts in the feces of GR-fed chickens. Our data showed that GR extracts had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of novel anticoccidial drugs.

Keyword

Anticoccidial activity; coccidiosis; eimeria; eimeria tenella; galla rhois
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