J Korean Med Sci.  1994 Dec;9(6):507-512. 10.3346/jkms.1994.9.6.507.

Five cases of cytomegalovirus infection detected by in situ hybridization and antigenemia assay

• Yoo JH
• Choi JY
• Kim YR
• Choi YJ
• Shim SI
• Kim HK
• Yang CW
• Kim YS
• Hahn CW
• Shin WS
• Park CW
• Kang MW
• Kim CC
• Bang BK
• Kim DJ

• KMID: 644844
• DOI: http://doi.org/10.3346/jkms.1994.9.6.507

Abstract

We report five cases of cytomegalovirus infection in immunocompromised patients which were detected by either cytomegalovirus antigenemia assay or in situ hybridization. Four cases had leukemia and the other had chronic renal failure. All the three BMT recipients suffered from GvHD. Interestingly, there was an unique case of CMV disease without a history of BMT, which reminded us that CMV could attack immunocompromised patients who had not undergone transplantation, too. Four out of five cases died. We think that cytomegalovirus infection or disease should not be regarded as a minor problem in post-transplantation infection in Korea.

Keyword

Cytomegalovirus; Bone Marrow; Transplantation; In Situ Hybridization

MeSH Terms

Adolescent
Adult
Antigens, Viral/*blood
*Bone Marrow Transplantation
Case Report
Cytomegalovirus/*immunology
Cytomegalovirus Infections/complications/*diagnosis
Fatal Outcome
Graft vs Host Disease/complications
Human
Immunocompromised Host
In Situ Hybridization
Kidney Failure, Chronic/complications
Kidney Transplantation
Leukemia/*complications/therapy
Leukemia, Lymphocytic, Acute, L2/complications/therapy
Leukemia, Myelocytic, Acute/complications/therapy
Leukemia, Myeloid, Chronic/complications/therapy
Male
Viremia/*diagnosis