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Peripheral blood immune cell-based biomarkers in anti-PD-1/PD-L1 therapy

Kim KH, Kim CG, Shin EC

Immune checkpoint blockade targeting PD-1 and PD-L1 has resulted in unprecedented clinical benefit for cancer patients. Anti-PD-1/PD-L1 therapy has become the standard treatment for diverse cancer types as monotherapy or...
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Mycosis Fungoides and Variants of Mycosis Fungoides: A Retrospective Study of 93 Patients in a Chinese Population at a Single Center

Luo Y, Liu Z, Liu J, Liu Y, Zhang W, Zhang Y

BACKGROUND: Mycosis fungoides (MF) is the most common types of cutaneous T cell lymphoma. It typically presents with erythematous patches and plaques in the early stage and tumors and extracutaneous...
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Subcapsular Splenic Hemorrhage in Vivax Malaria

Im JH, Chung MH, Durey A, Lee JS, Kim TS, Kwon HY, Baek JH

In malaria, splenic rupture is a serious complication potentially leading to death. Subcapsular hemorrhage of spleen is thought to be an impending sign of splenic rupture; however, the characteristics of...
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Status epilepticus due to cerebral air embolism after the Valsalva maneuver

Lyou HJ, Lee HJ, Lee GY, Kim WJ

BACKGROUND: Cerebral air embolism is uncommon but potentially causes catastrophic events such as cardiac damage or even death. However, due to a low overall incidence, it may go undiagnosed. CASE REPORT:...
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Higher Fatality for Severe Fever with Thrombocytopenia Syndrome Complicated by Hemophagocytic Lymphohistiocytosis

Jung IY, Ahn K, Kim J, Choi JY, Kim HY, Uh Y, Kim YK

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious zoonosis caused by the SFTS virus. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome associated with excessive immune activation. Cytokine storms...
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Endovascular Exclusion of Hepatic Artery Pseudoaneurysm after Living-Donor Liver Transplantation with a Stent-Graft Using Conical Remodeling: A Case Report

Baek SD, Kang UR, Kim YH

Hepatic artery complications after liver transplantation include hepatic artery thrombosis, stenosis, pseudoaneurysm (PA), and others. Among these complications, hepatic artery PA is reported to have a low incidence, but it...
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Antibacterial effect of lidocaine in various clinical conditions

Kim HT, Lim SW, Yim KH, Park SH, Choi JH, Bae YM, Shin ID, Shin YD

BACKGROUND: Infection, one of the complications associated with procedures, can cause fatal outcomes for patients. Although the local anesthetic agent we use is less susceptible to infection due to its...
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Tick killing in situ before removal to prevent allergic and anaphylactic reactions in humans: a cross-sectional study

Taylor BW, Ratchford , van Nunen , Burns B

BACKGROUND: Tick anaphylaxis is a potentially fatal outcome of improper tick removal and management. OBJECTIVE: To investigate whether killing ticks in-situ with ether-containing sprays or permethrin cream, before careful removal by...
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Disseminated Cryptococcosis Incorrectly Managed: a Case Report

Maleb A, Hami A, Ben Lahlou Y, Lamrabat S, Rifai S, Rahmani N, Bensalah M, Frikh M, Lemnouer A, Elouennass M

Disseminated cryptococcosis is a rare fungal infection, which mainly occurs in immunocompromised patients, and the diagnosis is difficult. Therefore, it is less likely to be considered in immunocompetent patients. Here,...
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Cerebral Air Embolism after Central Venous Catheter Removal in a Patient with a Patent Foramen Ovale: A Case Report and Literature Review

Hahn HJ, Lee GJ, Kim KH, Lee KE, Shim JC, Hwang DH, Kim HK

Central venous catheterization is a routinely performed procedure in clinical practice. While cerebral air embolism after the removal of the central venous catheter is very rare, it is one of...
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Oculomotor and Abducens Nerve Palsy Complicated by Cavernous Sinus Thrombophlebitis Resulting from Acute Sinusitis

Kang JY, Kim JJ, Choi IJ, Lee MC

Cavernous sinus thrombophlebitis is a rare complication of paranasal sinusitis. The disease can result in a fatal outcome if not treated with proper antibiotics or surgical intervention. Recently, we experienced...
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Iatrogenic Tension Pneumothorax after Surgical Tracheostomy in a Child with Idiopathic Subglottic Stenosis: case report

Park SY, Yim WJ, Jeong JH, Kim J, Lee SC, Choi SR, Lee JH, Chung CJ

Tracheostomy is increasingly performed in children for upper airway anomalies. Here, an 18-month-old child (height 84.1 cm, weight 12.5 kg) presented to the emergency department with dyspnea, stridor, and chest...
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Massive Duodenal Bleeding after the Migration of Endovascular Coils into the Small Bowel

Choi CJ, Lim H, Kim DS, Jeong YS, Park SY, Kim JE

Among gastrointestinal emergencies, acute upper gastrointestinal bleeding remains a challenging clinical problem owing to significant patient morbidity and costs involved in management. Endoscopic hemostatic therapy is the mainstay of treatment...
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Variability of Platelet Reactivity on Antiplatelet Therapy in Neurointervention Procedure

Yi HJ, Hwang G, Lee BH

As more intracranial aneurysms and other cerebrovascular pathologies are treated with neurointervention procedure, thromboembolic events that frequently lead to serious neurological deficit or fatal outcomes are increasing. In order to...
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Short-term Outcomes of Ceramic Coated Metal-on-Metal Large Head in Total Hip Replacement Arthroplasty

Kim WY, Ko MS, Lee SW, Kim KS

PURPOSE: This study characterizes the short-term outcomes of ceramic coated metal-on-metal (MoM) large head total hip arthroplasty (THA) in prospectively selected patients aged 70 to 75 years. MATERIALS AND METHODS: Eighteen...
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Complete Recovery of Oxysterol 7α-Hydroxylase Deficiency by Living Donor Transplantation in a 4-Month-Old Infant: the First Korean Case Report and Literature Review

Hong J, Oh SH, Yoo HW, Nittono H, Kimura A, Kim KM

Oxysterol 7α-hydroxylase deficiency is a very rare liver disease categorized as inborn errors of bile acid synthesis, caused by CYP7B1 mutations. As it may cause rapid progression to end-stage liver...
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Comparison of the Utility of dnaJ and 16S rDNA Sequences for Identification of Clinical Isolates of Vibrio Species

Choi IS, Moon DS, Park G, Kang SH, Kim CM, Ahn YJ, Kim DM, Yun NR, Lim DH, Shin SH, Kook JK, Chang YH, Jang SJ

BACKGROUND: Among the many Vibrio species that can cause infections in humans, several species can cause a fatal outcome. Therefore, accurate identification of Vibrio species is very important. Since some...
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Cerebral and Coronary Air Embolism after Percutaneous Needle Aspiration Biopsy of Lung

Shin MC, Ohk TG, Cho JH, Moon JB, Park CW, Kim KE, Yang GE, Lee HY

Percutaneous needle aspiration biopsy is a relatively simple and safe procedure for the diagnosis of lung and mediastinal lesions. Systemic air embolism during and after percutaneous needle aspiration biopsy of...
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Solid Freeform Techniques Application in Bone Tissue Engineering for Scaffold Fabrication

Shivalkar , Singh S

Solid freeform techniques are revolutionising technology with great potential to fabricate highly organized biodegradable scaffolds for damaged tissues and organs. Scaffolds fabricated via Solid freeform (SFF) techniques have more pronounced...
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Experience of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in a Regional Hospital: 70 Cases in 7 Years

Lee J, Kim JW

BACKGROUND/AIMS: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions that frequently result in fatal outcomes. We investigated cases of SJS and TEN in a regional...
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