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Treatment of congenital cytomegalovirus infection

Shim GH

Congenital cytomegalovirus (CMV) is the most common cause of congenital infection worldwide, the most common nongenetic cause of sensorineural hearing loss in children, and a cause of neurodevelopmental disorders in...
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The Multifaceted Clinical Characteristics of Congenital Cytomegalovirus Infection: From Pregnancy to Long-Term Outcomes

Kim Y, Kim Ym, Kim DR, Kim HG, Sung JH, Choi SJ, Oh Sy, Kim YJ, Chang YS, Kim D, Kim JS, Moon IJ, Roh CR

Background: The aim of this study was to capture multifaceted clinical characteristics of congenital cytomegalovirus (CMV) infection from diagnosis to treatment using a multidisciplinary approach including obstetrics, pediatrics, pathology, and...
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Infectious complications in patients with inflammatory bowel disease in Asia: the results of a multinational web-based survey in the 8th Asian Organization for Crohn’s and Colitis meeting

Jun YK, Koh SJ, Myung DS, Park SH, Ooi CJ, Sood A, Im JP

Background/Aims: Infectious complications are major concerns when treating patients with inflammatory bowel disease (IBD). This study evaluated clinical differences across countries/regions in the management of infectious diseases in patients with...
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Proven Cytomegalovirus Colitis Associated with Dasatinib Administration in Two Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients

Kim JM, Kang HM, Yoo IH, Lee DG, Chung NG, Cho B

Gastrointestinal (GI) bleeding is a rare adverse event of dasatinib, which is known to be caused by dasatinib-induced colitis, severe thrombocytopenia, and platelet dysfunction. We present two cases of pediatric patients...
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Cutaneous Cytomegalovirus Infection Presenting As Recalcitrant Bullous Pemphigoid Lesion

Baek G, Koo T, Kim MS, Jue MS

Cytomegalovirus (CMV) infection is common among immunocompromised hosts; however, its cutaneous manifestation is considered rare in comparison to internal organ involvement. Clinical manifestations of cutaneous CMV infection generally include perioral...
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Case of Pseudomembranous Colitis Caused by a Clostridioides difficile Infection Concomitant with Cytomegalovirus colitis Mimicking Ischemic Colitis

Kim HS, Kim HM, Gweon TG

A Clostridioides difficile infection (CDI) is one of the major nosocomial diarrheal diseases. Pseudomembranous colitis (PMC) is a characteristic endoscopic finding of CDI, manifested by white or yellowish plaque covering...
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Emergency gastrointestinal tract operation associated with cytomegalovirus infection

Kim S, Yoon KW, Gil E, Yoo K, Choi KJ, Park CM

Purpose: Cytomegalovirus (CMV) infection is common in immunocompromised patients. Enterocolitis caused by CMV infection can lead to perforation and bleeding of the gastrointestinal (GI) tract, which requires emergency operation. We...
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Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome

Lee JY, Park Jw, Park JY

Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In...
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Performance Evaluation of the ELITe InGenius System for Detecting Cytomegalovirus, EpsteinBarr Virus, and BK Virus Infections

Woo KS, Han JY

Background: The ELITe-MGB Kit (ELITech Group, Italy) is a qualitative and quantitative nucleic acid amplification assay used for the detection and quantification of various viruses, especially in the clinical management...
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A Comparative Study Between Cytomegalovirus Immunoglobulin M-Positive and CMV Immunoglobulin M-Negative Biliary Atresia in Infants Attending a Tertiary Care Hospital in Bangladesh

Akter S, Karim ASMB, Mazumder MW, Rukunuzzaman M, Nahid KL, Dey BP, Sayeed M, Rahman AZMR, Fathema K, Khadga M

Purpose: Perinatal cytomegalovirus (CMV) infection can lead to biliary atresia (BA) in different entities. This study aimed to compare the clinical, hematological, biochemical, and histological features of infants with BA...
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Cytomegalovirus Infection in Patients with Inflammatory Bowel Disease

Lee J

A diagnostic evaluation for cytomegalovirus (CMV) infection is required in patients with inflammatory bowel disease (IBD) who do not respond to steroid or immunomodulatory treatment. However, there is no consensus...
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Cytomegalovirus-Specific Immunotherapy for Glioblastoma Treatments

Ahn J, Shin C, Kim YS, Park JS, Jeun SS, Ahn S

Over the last two decades, numerous studies have investigated the presence of human cytomegalovirus (CMV) within glioblastoma or gliomas; however, the results are severely conflicting. While a few researchers have...
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Hearing and Neurodevelopmental Out comes in Preterm Infants with Post­natal Cytomegalovirus Infection

Kim YJ, Shin SH, Kim EK, Kim HS

Objective: We aimed to investigate whether preterm infants with postnatal cytomegalovirus (CMV) infection have unfavorable hearing and neurodevelopmental outcomes. We also tried to find the difference between symptomatic and asymptomatic...
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Antiviral Resistance in Human Cytomegalovirus Due to UL54 Mutations Without UL97 Mutations

Park K, Hur KH, Sung H, Choi SH, Kim MN

Background: The concurrent detection of human cytomegalovirus (CMV) with UL97 and UL54 mutations is crucial for prescribing adequate antiviral treatment when drug-resistant CMV infection is suspected. We investigated the frequency...
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Cytomegalovirus Immune Recovery Retinitis with Similarity to Acute Retinal Necrosis

Cho YW, Hong CM, Choi YJ, Yoo WS, Chung IY

Purpose: To describe successful treatment of cytomegalovirus immune recovery retinitis, with similarity to acute retinal necrosis, in patients with acquired immunodeficiency syndrome (AIDS) in the immune recovery stage. Case summary: A...
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Laboratory diagnostic testing for cytomegalovirus infection in solid organ transplant patients

Lee H, Oh EJ

Human cytomegalovirus (CMV) infection, which is one of the most common complications in transplant recipients, increases the risk of graft loss and rejection. Laboratory strategies for diagnosing CMV infection rely...
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Cytomegalovirus Retinitis in Immunocompetent Patients with Diabetes Mellitus

Cho YW, Won JY

Purpose: We report five cases of cytomegalovirus (CMV) retinitis in immunocompetent patients with diabetes mellitus (DM). Methods: This was a retrospective observational case series of five immunocompetent patients with CMV retinitis....
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Predictor of Liver Biochemistry Improvement in Patients with Cytomegalovirus Cholestasis after Ganciclovir Treatment

Puspita G, Widowati T, Triono A

Purpose: Cholestasis resulting from cytomegalovirus (CMV)-induced hepatitis manifests in 40% of patients with a CMV infection. Ganciclovir treatment in children with CMV infections has proven to be highly effective. Until...
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Concurrent cytomegalovirus enteritis and atypical hemolytic uremic syndrome with gastrointestinal tract involvement: a case report

Kim MH, Cho MH, Ahn YH, Bae JM, Moon JS, Kang HG

Atypical hemolytic uremic syndrome (aHUS) is a rare disease caused by complement dysregulation that may involve the extra-renal system. Without appropriate prophylactic treatment, aHUS commonly recur after kidney transplantation (KT)....
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High mucosal cytomegalovirus DNA helps predict adverse short-term outcome in acute severe ulcerative colitis

Jain S, Namdeo D, Sahu P, Kedia S, Sahni P, Das P, Sharma R, Gupta V, Makharia G, Dar L, Travis SP, Ahuja V

Background/Aims: Predictors of short-term outcome of intravenous (IV) steroid therapy in acute severe ulcerative colitis (ASUC) have been well described, but the impact of cytomegalovirus (CMV) infection as a predictor...
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