J Korean Neurosurg Soc.
1986 Dec;15(4):779-786.
Effect of Pinealectomy on the Renin-Angiotensin System in Sprague-Dawley Rats
- Affiliations
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- 1Department of Neurosurgery, College of Medicine, Won Kwang University, Chollabuk-do, Korea.
Abstract
- Experiments were performed to investigate the effects of pinealectomy on the renin-angiotensin system in Sprague-Dawley rats. The results obtained were as follows. 1) There was no differences of systolic blood pressure, heart rate, water intake, and plasma electrolytes between pinealectomized and sham-operated rats. 2) Renin activity in plasma and pituitary gland did not differ in two experimental groups. 3) The pituitary gland contained the renin activity of about 50pg AI/hr/mg of wet weight. The results suggest that the pineal gland has no correlation with cardiovascular and renin-angiotensin system.
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