J Korean Acad Oral Health.  2015 Jun;39(2):152-157. 10.11149/jkaoh.2015.39.2.152.

Relationship between periodontal status and blood count and anemia in adults: Based on the 5th Korea National Health and Nutrition Examination Survey

• Jo MJ
• Ma JK
• Shin AR
• Dong F
• Song KB
• Choi YH
• Lee HK

• KMID: 2321521
• DOI: http://doi.org/10.11149/jkaoh.2015.39.2.152

Abstract

OBJECTIVES
Periodontal disease is an inflammatory disease fundamentally initiated by chronic bacterial infection. Just as the periodontal tissues mount an immune inflammatory response to bacteria and their products, systemic challenges owing to these inflammatory agents also induce a major vascular response. It is proposed that periodontitis also needs to be considered as a chronic disease that may decrease erythrocyte count and consequently lower hemoglobin concentration (Hb%). Therefore, the aim of this study was to elucidate the correlation between anemia and blood cell count according to periodontal state.
METHODS
Data from the Fifth Korea National Health and Nutrition Examination Survey (KNHNES) were used to analyze the prevalence of anemia and blood cell counts according to the periodontal status. Complex logistic regression analysis was used to assess the relationship of anemia with periodontal status. The data were analyzed using t-test, ANOVA, and logistic regression using SPSS, and 95% confidence intervals were computed.
RESULTS
A significant difference was observed for gingivitis (odds ratio [OR], 1.436 [95% confidence interval [CI], 1.072-1.924]) but not for periodontitis (OR, 1.353 (95% CI, 0.947-1.934).
CONCLUSIONS
The present study provides further evidence that gingivitis has systemic effects and may cause anemia. However, periodontitis was not significantly associated with anemia. Further, there was no significant difference in periodontal status after adjustment for age, gender, and other factors.

Keyword

Anemia; Blood cell; Periodontal disease

MeSH Terms

Adult*
Anemia*
Bacteria
Bacterial Infections
Blood Cell Count
Blood Cells
Chronic Disease
Erythrocyte Count
Gingivitis
Humans
Korea
Logistic Models
Nutrition Surveys*
Periodontal Diseases
Periodontitis
Prevalence

Reference

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