J Korean Acad Oral Health.  2016 Dec;40(4):215-221. 10.11149/jkaoh.2016.40.4.215.

Cross-sectional study of the association of vitamins C and D with periodontal status

Affiliations
  • 1Department of Preventive and Public Health Dentistry, College of Dentistry, Wonkwang University, Iksan, Korea. dhdh@wonkwang.ac.kr
  • 2WBMI and Institute of Wonkwang Dental Research, College of Dentistry, Wonkwang University, Iksan, Korea.

Abstract


OBJECTIVES
The purpose of this study was to examine the association between vitamin C, vitamin D, and periodontal diseases in adults.
METHODS
The data used for analysis were obtained from the sixth Korean National Health and Nutrition Examination Survey (2013-2014). Subjects were 2,702 adults aged from 19 to 64 years. Complex Chi-square tests and complex logistic regression analyses were used to assess the association between vitamins and periodontal status.
RESULTS
There is no statistically significant association between vitamin C intake and periodontal status. Periodontal status of subjects with a low vitamin D (25-hydroxyvitamin D) level was better than that of the subjects with a high level (P<0.05). However, multivariate analysis demonstrated that this association is not statistically significant.
CONCLUSIONS
More follow-up studies are necessary to determine the association of the vitamins C and D with the periodontal diseases.

Keyword

Adults; Periodontal diseases; Sixth Korean National Health and Nutrition Examination Survey; Vitamin C; Vitamin D

MeSH Terms

Adult
Ascorbic Acid
Cross-Sectional Studies*
Follow-Up Studies
Humans
Logistic Models
Multivariate Analysis
Nutrition Surveys
Periodontal Diseases
Vitamin D
Vitamins*
Ascorbic Acid
Vitamin D
Vitamins

Reference

References

1. Nunn ME. Understanding the etiology of periodontitis: an overview of periodontal risk factors. Periodontol 2000. 2003; 32:11–23.
Article
2. Palacios C, Joshipura K, Willett W. Nutrition and health: guidelines for dental practitioners. Oral Dis. 2009; 15:369–381.
Article
3. Papas AS, Palmer CA, Rounds MC, Herman J, McGandy RB, Hartz SC, et al. Longitudinal relationships between nutrition and oral health. Ann N Y Acad Sci. 1989; 561:124–142.
Article
4. Melnick SL, Alvarez JO, Navia JM, Cogen RB, Roseman JM. A case-control study of plasma ascorbate and acute necrotizing ulcerative gingivitis. J Dent Res. 1988; 67:855–860.
Article
5. Staudte H, Sigusch BW, Glockmann E. Grapefruit consumption improves vitamin C status in periodontitis patients. Br Dent J. 2005; 199:213–217.
Article
6. Paek KW, Lee SJ. Correlation between vitamin C intake and periodontal disease: The fifth Korea National Health and Nutrition Examination Survey, 2010. J Korea Acad Oral Health. 2014; 38:82–89.
Article
7. Berg RA, Steinmann B, Rennard SI, Crystal RG. Ascorbate deficiency results in decreased collagen production: under-hydroxylation of proline leads to increased intracellular degradation. Arch Biochem Biophys. 1983; 226:681–686.
Article
8. Alfano MC, Miller SA, Drummond JF. Effect of ascorbic acid deficiency on the permeability and collagen biosynthesis of oral mucosal epithelium. Ann N Y Acad Sci. 1975; 258:253–263.
Article
9. Alvares O, Altman LC, Springmeyer S, Ensign W, Jacobson K. The effect of subclinical ascorbate deficiency on periodontal health in nonhuman primates. J Periodontal Res. 1981; 16:628–636.
Article
10. Woolfe SN, Kenney EB, Hume WR, Carranza FA. Relationship of ascorbic acid levels of blood and gingival tissue with response to periodontal therapy. J Clin Periodontol. 1984; 11:159–165.
Article
11. Leggott PJ, Robertson PB, Rothman DL, Murray PA, Jacob RA. The effect of controlled ascorbic acid depletion and supplementation on periodontal health. J Periodontol. 1986; 57:480–485.
Article
12. Amarasena N, Ogawa H, Yoshihara A, Hanada N, Miyazaki H. Serum vitamin C-periodontal relationship in community-dwelling elderly Japanese. J Clin Periodontol. 2005; 32:93–97.
Article
13. Dietrich T, Joshipura KJ, Dawson-Hughes B, Bischoff-Ferrari HA. Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population. Am J Clin Nutr. 2004; 80:108–113.
14. Gaugris S, Heaney RP, Boonen S, Kurth H, Bentkover JD, Sen SS. Vitamin D inadequacy among post-menopausal women: a systematic review. QJM. 2005; 98:667–676.
Article
15. Dietrich T, Nunn M, Dawson-Hughes B, Bischoff-Ferrari HA. Association between serum concentrations of 25-hydroxyvitamin D and gingival inflammation. Am J Clin Nutr. 2005; 82:575–580.
Article
16. McMahon L, Schwartz K, Yilmaz O, Brown E, Ryan LK, Diamond G. Vitamin D-mediated induction of innate immunity in gingival epithelial cells. Infect Immun. 2011; 79:2250–2256.
Article
17. Bae IK, Kwon HJ, Kim IS, Hong HS. Dental biochemistry and nutrition. Seoul: Komoonsa;2015. p. 121.
18. Lee SH, Roh SC. Vitamin D level in blood of menopausal women over 50 and the relation with the proportion requiring dental scaling. J Dent Hyg Sci. 2013; 13:393–402.
19. Ministry of Health and Welfare. Dietary Reference Intakes for Koreans 2015. Sejong: Ministry of Health and Welfare;2015. p. 277–313. 361.
20. Paek KW, Lee SJ, Back JH. A factor of periodontal disease and dietary patterns in Korean adults using data from Korea National Health and Nutrition Examination Survey Ⅴ. J Korea Acad Oral Health. 2015; 39:280–287.
21. Koo SM, Park YJ, Hwang JY. Association between consumption of fruits and vitamin c and generalized periodontitis in Korean adults: the 2007-2010 Korean National Health and Nutrition Examination Surveys. Korean J Dent Mater. 2013; 40:77–85.
22. Nishida M, Grossi SG, Dunford RG, Ho AW, Trevisan M, Genco RJ. Dietary vitamin C and the risk for periodontal disease. J Periodontol. 2000; 71:1215–1223.
Article
23. Lee HJ, Je DI, Won SJ, Paik DI, Bae KH. Association between vitamin D deficiency and periodontal status in current smokers. Community Dent Oral Epidemiol. 2015; 43:471–478.
Article
24. Amano Y, Komiyama K, Makishima M. Vitamin D and periodontal disease. J Oral Sci. 2009; 51:11–20.
Article
25. Miley DD, Garcia MN, Hildebolt CF, Shannon WD, Couture RA, Anderson Spearie CL, et al. Cross-sectional study of vitamin D and calcium supplementation effects on chronic periodontitis. J Peri-odontol. 2009; 80:1433–1439.
Article
26. Garcia MN, Hildebolt CF, Miley DD, Dixon DA, Couture RA, Spearie CL, et al. One-year effects of vitamin D and calcium supplementation on chronic periodontitis. J Periodontol. 2011; 82:25–32.
Article
27. Bashutski JD, Eber RM, Kinney JS, Benavides E, Maitra S, Braun TM, et al. The impact of vitamin D status on periodontal surgery outcomes. J Dent Res. 2011; 90:1007–1012.
Article
Full Text Links
  • JKAOH
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr