Yeungnam Univ J Med.  1993 Dec;10(2):518-524.

Hyperinfection of strongyloides stercoralis

• Shin KC
• Chun JH
• Park CW
• Lee CK
• Lee HW

Abstract

Strongylodiasis is universal in distribution but is most abundant in countries with a tropical climate. Although infestation by Strongyloides stercoralis is usually limited to the intestines, dessemination of this helminth in debilitated host can be lead to death with various clinical disorders. characterized by profound malabsorption, diarrhea, electrolyte imbalance, gram negative or opportunistic fungal sepsis, coma and death. Cell-mediated immunity contributing significantly to the control of helminthic infections, may be suppressed by carcinoma, immunosuppressive chemotherapy and use of corticosteroids. Diagnosis of Strongyloidiasis is achieved by an examination of samples of feces, duodenal aspirates and sputum of patients for Strongyloides stercoralis. Treatment of strongyloidiasis is twofold : correction of the immunosuppressive state by withdrawal of immunosuppressive drug, if possible, and vigorous treatment with thiabendazole. Testing for strongyloidiasis is especially recommanded before treating a patients should be monitored for infection by Strongyloides stercoralis and other opportunistic infection. We are reporting a case patient with Strongyloides stercoralis hyperinfection and pulmonary tuberculosis who had been. used corticosteroid for persisting polyarthritis.

MeSH Terms

Adrenal Cortex Hormones
Arthritis
Coma
Diagnosis
Diarrhea
Drug Therapy
Feces
Helminths
Humans
Immunity, Cellular
Intestines
Opportunistic Infections
Sepsis
Sputum
Strongyloides stercoralis*
Strongyloides*
Strongyloidiasis
Thiabendazole
Tropical Climate
Tuberculosis, Pulmonary
Adrenal Cortex Hormones
Thiabendazole