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Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome

Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK

BACKGROUND/AIMS: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated...
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Antibiotics-Induced Dysbiosis of Intestinal Microbiota Aggravates Atopic Dermatitis in Mice by Altered Short-Chain Fatty Acids

Kim HJ, Lee SH, Hong SJ

PURPOSE: Alterations in the intestinal microbiota in early life affects the development of atopic dermatitis (AD) in humans. This study aimed to further investigate the effects of gut dysbiosis in...
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Excretion of Toxoplasma gondii oocysts from Feral Cats in Korea

Ahn KS, Ahn AJ, Park SI, Sohn WM, Shim JH, Shin SS

Sporulated oocysts from the feces of infected cats with Toxoplasma gondii can cause detrimental disease in both humans and animals. To investigate the prevalence of feral cats that excrete T....
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Differential Change in the Prevalence of the Ascaris, Trichuris and Clonorchis infection Among Past East Asian Populations

Zhan X, Yeh HY, Shin DH, Chai JY, Seo M, Mitchell P

As we learn more about parasites in ancient civilizations, data becomes available that can be used to see how infection may change over time. The aim of this study is...
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Virus-like Particle Vaccine Containing Toxoplasma gondii Rhoptry Protein 13 Induces Protection against T. gondii ME49 Infection in Mice

Kang HJ, Chu KB, Lee SH, Kim MJ, Park H, Jin H, Quan FS

Toxoplasma gondii can infect humans worldwide, causing serious diseases in pregnant women and immunocompromised individuals. T. gondii rhoptry protein 13 (ROP13) is known as one of the key proteins involved...
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Colonic Dysmotility in Murine Partial Colonic Obstruction Due to Functional Changes in Interstitial Cells

Wang Q, Zang J, Huang X, Lu H, Xu W, Chen J

  • KMID: 2460488
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):589-601.
  • doi: 10.5056/jnm19136
BACKGROUND/AIMS: Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO)...
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The difference of detection rate of avian influenza virus in the wild bird surveillance using various methods

Kim GS, Kim TS, Son JS, Lai VD, Park JE, Wang SJ, Jheong WH, Mo IP

Korea is located within the East Asian-Australian flyway of wild migratory birds during the fall and winter seasons. Consequently, the likelihood of introduction of numerous subtypes and pathotypes of the...
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Traditional Medicine Doctor Kim Gwangjin's Battle against Jaundice during the Japanese Colonial Period

Oh C

This study aims to examine how traditional medicine doctors (醫生) of the Japanese colonial period in Korea treated patients and their own diseases with traditional medicine (漢方) and Western medicine...
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Is stool frequency associated with the richness and community composition of gut microbiota?

Kwon HJ, Lim JH, Kang D, Lim S, Park SJ, Kim JH

BACKGROUND/AIMS: Recently, a number of studies have reported that the gut microbiota could contribute to human conditions, including obesity, inflammation, cancer development, and behavior. We hypothesized that the composition and...
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Clinical Significance of Inflammatory Biomarkers in Acute Pediatric Diarrhea

Park Y, Son M, Jekarl DW, Choi HY, Kim SY, Lee S

PURPOSE: The aim of this study was to evaluate the clinical significance of inflammatory biomarkers in acute infectious diarrhea among children. METHODS: Clinical parameters including fever, bacterial and viral etiology based...
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The novel latex agglutination turbidimetric immunoassay system for simultaneous measurements of calprotectin and hemoglobin in feces

Hiraoka S, Takashima , Inokuchi T, Nakarai A, Takahara M, Harada K, Seki Y, Watanabe K, Kato J, Okada H

BACKGROUND/AIMS: Fecal calprotectin (Fcal) as well as the fecal immunochemical test (FIT) are useful biomarkers for detecting activity and mucosal healing in inflammatory bowel diseases. Here, we report the performance...
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Effect of Sulgidduk containing pine needle juice on lipid metabolism in high fat-cholesterol diet induced dyslipidemic rats

Lee Y, Park JH, Park E

PURPOSE: Dyslipidemia is a major risk factor for cardiovascular disease. Pine needles (Pinus densiflora seib et Zucc) are a traditional medicine used to treat dyslipidemia in clinical settings. This study...
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Four New Records of Ascomycete Species from Korea

Nguyen TT, Pangging M, Lee SH, Lee HB

While evaluating fungal diversity in freshwater, grasshopper feces, and soil collected at Dokdo Island in Korea, four fungal strains designated CNUFC-DDS14-1, CNUFC-GHD05-1, CNUFC-DDS47-1, and CNUFC-NDR5-2 were isolated. Based on combination...
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Relationships between Virulence Factors and Antimicrobial Resistance among Escherichia coli Isolated from Urinary Tract Infections and Commensal Isolates in Tehran, Iran

Karam MR, Habibi M, Bouzari S

OBJECTIVES: Uropathogenic Escherichia coli (UPEC) are the major cause of urinary tract infections (UTIs). Here, we determined whether sensitivity to antibiotics was related to the prevalence of iron scavenging genes,...
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The Impact of the Outcome of Treating a High Anal Fistula by Using a Cutting Seton and Staged Fistulotomy on Saudi Arabian Patients

Shirah BH, Shirah HA

PURPOSE: A cutting seton is used after a partial distal fistulotomy to treat patients with a high exrasphincteric fistula in ano to avoid fecal incontinence and recurrence. In Saudi Arabia,...
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Analysis of Syndecan-2 Methylation in Bowel Lavage Fluid for the Detection of Colorectal Neoplasm

Park YS, Kim DS, Cho SW, Park JW, Jeon SJ, Moon TJ, Kim SH, Son BK, Oh TJ, An S, Kim JH, Chae JD

BACKGROUND/AIMS: Syndecan-2 (SDC2) methylation was previously reported as a sensitive serologic biomarker for the early detection of colorectal cancer (CRC). The purpose of this study was to investigate whether SDC2...
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Hyperlipidemic Inhibitory Effects of Phellinus pini in Rats Fed with a High Fat and Cholesterol Diet

Im KH, Choi J, Baek SA, Lee TS

This study evaluated the in vitro and in vivo hypolipidemic effects of the medicinal mushroom Phellinus pini. The methanol extract (ME) of the fruiting body of Ph. pini was active...
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Foodborne Illness Outbreaks in Gyeonggi Province, Korea, Following Seafood Consumption Potentially Caused by Kudoa septempunctata between 2015 and 2016

Kim JJ, Ryu S, Lee H

OBJECTIVES: Investigations into foodborne illness, potentially caused by Kudoa septempunctata, has been ongoing in Korea since 2015. However, epidemiological analysis reporting and positive K septempunctata detection in feces in Korea...
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What Is the Future of Impedance Planimetry in Gastroenterology?

Gregersen , Lo KM

  • KMID: 2413094
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):166-181.
  • doi: 10.5056/jnm18013
The gastrointestinal (GI) tract is efficient in transporting ingested material to the site of delivery in healthy subjects. A fine balance exists between peristaltic forces, the mixing and delivery of...
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Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea

Kim YH, Park BJ, Ahn HS, Han SH, Go HJ, Kim DH, Lee JB, Park SY, Song CS, Lee SW, Choi IS

Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an important reservoir of these genotypes. A survey of 14 pig...
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