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Cortisol Measurements in Cushing's Syndrome: Immunoassay or Mass Spectrometry?

Casals G, Hanzu FA

Determination of cortisol levels in the urine (24 hours urine free cortisol), saliva (late-night), or serum (total cortisol after dexamethasone suppression) is recommended to screen for Cushing's syndrome (CS). This...
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Hospitalization Due to Asthma Exacerbation: A China Asthma Research Network (CARN) Retrospective Study in 29 Provinces Across Mainland China

Lin J, Xing B, Tang H, Yang L, Yuan Y, Gu Y, Chen P, Liu X, Zhang J, Liu H, Wang C, Zhou W, Sun D, Chen Y, Chen Z, Huang M, Lin Q, Hu C, Yang X, Huo J, Ye X, Zhou X, Jiang P, Zhang W, Huang Y, Dai L, Liu R, Cai S, Xu J, Zhou J, on behalf of China Asthma Research Network

PURPOSE: Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is...
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Successful Treatment with Rituximab and Immunoadsorption for an Auto-Antibody Induced Bile Salt Export Pump Deficiency in a Liver Transplanted Patient

Quintero J, Juamperez , Gonzales E, Julio E, Mercadal-Hally M, Collado-Hilly M, Marín-Sánchez A, Charco R

We present an 8 years old girl who was diagnosed at 6 months of age of Progressive Familial Intrahepatic Cholestasis type 2. Although liver transplantation (LT) was classically considered curative...
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Exhaled Nitric Oxide in Patients with Stable Chronic Obstructive Pulmonary Disease: Clinical Implications of the Use of Inhaled Corticosteroids

Jo YS, Choe J, Shin SH, Koo HK, Lee WY, Kim YI, Ra SW, Yoo KH, Jung KS, Park HY, Park YB

BACKGROUND: Fractional exhaled nitric oxide (FeNO) is regarded as a potential biomarker for identifying eosinophilic inflammation. We aimed to evaluate the clinical implication of FeNO and its influence on inhaled...
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Recurrent cervicocephalic artery dissection in a patient with Churg-Strauss syndrome treated with long-term corticosteroid therapy

Kim HJ, Park SR, Bang OY

Churg-Strauss syndrome (CSS) is known to mainly involve small vessels; thus, in the event of large-vessel disease, other causes must be taken into consideration. We report a case of CSS...
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Changes in Range of Motion after Intra-Articular Corticosteroid Injection in Frozen Shoulder: A Retrospective 3-Month Follow-Up Study

Cho HJ, Yoon SH, Kim M, Kim DH

OBJECTIVE: To examine (1) the degree of reduction of passive range of motion (PROM) on the affected side compared to that on the unaffected side and (2) the degree of...
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Hyaluronic acid has chondroprotective and joint-preserving effects on LPS-induced synovitis in horses

Neuenschwander HM, Moreira JJ, Vendruscolo CP, Fülber J, Seidel SR, Michelacci YM, Baccarin R

The intra-articular use of hyaluronic acid (HA) for the treatment of synovitis and osteoarthritis is still controversial. As a consequence, corticosteroids remain the most frequently employed therapeutic agents, despite their...
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Inhaled Corticosteroids and Placebo Treatment Effects in Adult Patients With Cough: A Systematic Review and Meta-analysis

Lee SE, Lee JH, Kim HJ, Lee BJ, Cho SH, Price D, Morice AH, Song WJ

PURPOSE: Inhaled corticosteroids (ICSs) are often considered an empirical therapy in the management of patients with cough. However, ICS responsiveness is difficult to interpret in daily clinical practice, as the...
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Inhaled Corticosteroids in Asthma and the Risk of Pneumonia

Kim MH, Rhee CK, Shim JS, Park SY, Yoo KH, Kim BY, Bae HW, Sim YS, Chang JH, Cho YJ, Lee JH

PURPOSE: Asthma is a common disease that is expensive and burdensome for patients. Inhaled corticosteroids (ICS) are the most important drugs for asthma treatment and are often prescribed long-term. However,...
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Future Risks in Patients With Severe Asthma

Song WJ, Lee JH, Kang Y, Joung WJ, Chung KF

A major burden of severe asthma is the future risk of adverse health outcomes. Patients with severe asthma are prone to serious exacerbation and deterioration of lung function and may...
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Risk of Pneumonia Associated With the Use of Inhaled Corticosteroids in Asthma

Kim SH

No abstract available.
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Are steroids required in the treatment of ganglion impar blockade in chronic coccydynia? a prospective double-blinded clinical trial

Sencan S, Edipoglu I, Demir FG, Yolcu G, Gunduz OH

BACKGROUND: Ganglion impar blockade is a reliable and effective treatment option used in patients with coccydynia. Our primary objective was to specify the role of corticosteroids in impar blockade. We...
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A Case of Primary Central Nervous System Vasculitis That Worsened Despite Early Corticosteroid Therapy

Yoon SY, Park KS, Park SH, Park JY

Primary central nervous system vasculitis (PCNSV) is rare, and the diagnosis is difficult to make because of its variable radiologic expressions. Early corticosteroid therapy often is effective. Herein we report...
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Immune-related Adverse Events: Overview and Management Strategies for the Use of Immune Checkpoint Inhibitors

Jeung HC, Oh SE, Kim JH

Recent studies on T cell immunology have been instrumental in developing therapies to overcome cancer immune escape, and immune checkpoint inhibitors have emerged as one of the most promising therapeutic...
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Severe Cutaneous Adverse Reactions: A Single-Center Retrospective Study of 173 Patients in China

Xu Z, Shen J, Yang Y, Yuan R, Xiang LF, Zhang C

BACKGROUND: Severe cutaneous adverse reactions (SCAR) to drugs are a crucial public health issue and the use of systemic corticosteroids in SCAR has been controversial. OBJECTIVE: To analyze clinical features, causative...
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A retrospective study of theophylline-based therapy with tracheal collapse in small-breed dogs: 47 cases (2013–2017)

Jeung SY, Sohn SJ, An JH, Chae HK, Li Q, Choi M, Yoon J, Song WJ, Youn HY

Theophylline acts as a bronchodilator and has an anti-inflammatory effect. In addition, theophylline can be applied in patients where there are concerns regarding the side-effects of corticosteroids. This retrospective case...
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Treatment patterns of knee osteoarthritis patients in Korea

Park HR, Cho SK, Im SG, Jung SY, Kim D, Jang EJ, Sung YK

BACKGROUND/AIMS: To evaluate the treatment patterns of knee osteoarthritis (OA) patients in South Korea. METHODS: Using the Korean nationwide claims database, all knee OA patients in Korea during 2014 were identified...
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Clinical outcomes and effects of treatment in older patients with idiopathic membranous nephropathy

Kim Y, Yoon HE, Chung BH, Choi BS, Park CW, Yang CW, Kim YS, Hong YA, Kim SY, Chang YK, Hwang HS

BACKGROUND/AIMS: Membranous nephropathy (MN) is the most common primary glomerular disease diagnosed in older patients. Few reports describe the clinical outcomes in older patients with idiopathic MN. METHODS: The outcomes of...
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A Case of Autoimmune Sensorineural Hearing Loss Responding to Cytotoxic Agent

Lee YW, Lee J, Kim MB, Chang SO

Autoimmune sensorineural hearing loss is a rare disease characterized by bilateral sensorineural hearing loss, some in a progressive pattern and others in idiopathic or fluctuating pattern, often accompanied by vestibular...
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Management of Candida Urinary Tract Infection in the Elderly

Kim SJ, Ryu JH, Kim YB, Yang SO

Candida urinary tract infections in elderly patients are becoming increasingly common. The risk factors for the development of candiduria include old age, use of broad-spectrum antibiotics, corticosteroids and indwelling urethral...
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