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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Lung Pathology in Septic Shock with Leukopenia

Huh GY

Sepsis-related deaths are occasionally encountered in forensic practice. However, forensic pathologists are reluctant to use the terminology “sepsis” or “septic shock” as a cause of death because of the lack...
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Association between Left Ventricular Systolic Dysfunction and Mortality in Patients with Septic Shock

Kim S, Lee JD, Kim BK, Kim YH, Kim JH

BACKGROUND: The impact of myocardial damage on the prognosis of patients with septic shock is not clearly elucidated because complex hemodynamic changes in sepsis obscure the direct relationship. We evaluated...
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Incidence of Hypotension after Discontinuation of Norepinephrine or Arginine Vasopressin in Patients with Septic Shock: a Systematic Review and Meta-Analysis

Song JU, Lee J, Park HK, Suh GY, Jeon K

BACKGROUND: There has been no consensus regarding the discontinuation order of vasopressors in patients recovering from septic shock treated with concomitant norepinephrine (NE) and arginine vasopressin (AVP). The aim of...
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The prognostic value of 1-hour bundle completion in septic shock patients

Jeong WI, Kim JS, Yu J, Kang J, Yu G, Cho Y, Jung S, Kim WY, Ryoo SM

OBJECTIVE: Since 2018, the surviving sepsis campaign recommended one-hour bundle therapy in septic shock patients. On the other hand, evidence for the effectiveness of bundle therapy has not been established....
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Treatment of intractable orofacial infection: Case reports

Kang DW, Yun PY, Kim YK

In severe cases, intractable infections in the orofacial area can lead to breathing difficulties due to closed airway, mediastinitis, and spread of infection along the blood vessels. Moreover, these conditions...
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The Clinical Investigation of Necrotizing Fasciitis in Burn Center

Kim E, Chun JW, Kim YM, Yoon JC, Lim HJ, Cho YS, Kim D, Hur J, Chun W

PURPOSE: The necrotizing fasciitis is a terrifying infectious disease that can rapidly spreads to surrounding tissues when fascia is infected and it can cause sepsis to death if not properly...
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Delta Neutrophil Index as an Early Marker of Sepsis in Burn Patients

Kim CM, Ha CM

PURPOSE: The immature granulocyte count has been reported to be a marker of infection and sepsis. The difference in leukocyte subfractions (delta neutrophil index, DNI) in ADVIA 2120 reflects the...
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Validation of quick sequential organ failure assessment score for poor outcome prediction among emergency department patients with suspected infection

Sohn YW, Jang HY, Park S, Lee Y, Cho YS, Park J, Chung H, Kim SI

OBJECTIVE: The quick sequential organ failure assessment (qSOFA) score, which includes mentation, systolic blood pressure, and respiratory rate, was developed to identify serious sepsis in out-of-hospital or emergency department (ED)...
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Eosinophil count and neutrophil-to-lymphocyte count ratio as biomarkers for predicting early-onset neonatal sepsis

Lee JH

No abstract available.
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Risk factors and Effect of Early Hypocarbia on the Development of Cystic Periventricular Leukomalacia in Very Low birth Weight Infants

Lee EY, Yeom JM, Lee SH, So CH, Oh YK

OBJECTIVE: To evaluate the risk factors and effect of early hypocarbia for the development of cystic periventricular leukomalacia (CPVL) in very low birth weight infants. METHODS: We reviewed medical records of...
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Trends of Mortality, Time, and Causes of Death in Preterm Infants

Jeon GW

OBJECTIVE: Although survival rate of preterm infants in Korea has increased in the past several decades, it seems to be stable recently. The objective of this study is to evaluate...
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Evaluation of the Early Onset Neonatal Sepsis according to Two Antenatal Group B Streptococcus Screening Methods: Risk-Based versus Universal Screening

Hong JY, Kim SH, Kim SM, Yee CA, Choi SJ, Oh SY, Roh CR

OBJECTIVE: The standard antenatal screening method for Group B Streptococcus (GBS) has not been established yet. Therefore, many practitioners in South Korea offer GBS screening to all pregnant women without...
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Perinatal Outcomes Following Prolonged Preterm Premature Rupture of Membranes before Limit of Viability - A Single Center Experience

Lee NH, Park JH, Bae JG

OBJECTIVE: To investigate maternal and neonatal outcomes following prolonged preterm premature rupture of membrane (PPROM) before limit of viability in a single center. METHODS: Thirty-two women with PPROM before 25 weeks'...
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Esophageal Perforation after Anterior Cervical Spine Surgery

Ko SB, Park JB, Song KJ, Lee DH, Kim SW, Kim YY, Jeon TS, Cho YJ

STUDY DESIGN: Retrospective case analyses. PURPOSE: To investigate the causes, diagnosis, and management of esophageal perforation, depending on the time of diagnosis. OVERVIEW OF LITERATURE: To date, few studies have addressed these...
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Sepsis

Lee Y, Cho YJ

Diagnosis and treatment criteria were recently updated based on the Sepsis-3 guidelines, which recommend the sequential organ failure assessment for accurate characterization of organ dysfunction. Large randomized controlled trials have...
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Cerebral Venous Sinus Thrombosis with Meningitis and Septicemia due to Haemophilus influenzae Type f in an Immunocompetent Child

Han H, Lee KJ, Yu HJ

Since the implementation of conjugate Haemophilus influenzae serotype b (Hib) vaccine, the rate of infections caused by Hib has dramatically decreased, and the proportion of infections caused by non-type b...
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Molecular Epidemiologic Study of a Methicillin-resistant Staphylococcus aureus Outbreak at a Newborn Nursery and Neonatal Intensive Care Unit

Kang HM, Park KC, Lee KY, Park J, Park SH, Lee DG, Kim JH

PURPOSE: This study aimed to investigate the molecular epidemiology of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak at a newborn nursery and neonatal intensive care unit (NICU). METHODS: During the outbreak, from...
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Symmetrical Digital Gangrene Resulting from Vasopressor Usage for the Treatment of Septic Shock: Case Reports

Song JH, Heo YM, Oh BH, Cha HJ

Symmetrical Digital Gangrene (SDG) is characterized by the sudden onset of peripheral, symmetrical gangrene in the absence of any major vascular occlusive disease. Catecholamine inotropes are frequently used for the...
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Optimal antimicrobial therapy and antimicrobial stewardship in sepsis and septic shock

Seok H, Park DW

The management of sepsis and septic shock remains challenging. The aim is to apply the optimal antimicrobial therapy and antimicrobial stewardship to patients in state of sepsis or septic shock....
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