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Association Between Atopic Dermatitis and Suicidal Behaviors in North Korean Adolescent Defectors From 2011 to 2019

Jang SY, Seo SR, Kim K, Choi HO, Lee CK

Objective To evaluate the association between atopic dermatitis (AD) and suicidal behaviors in adolescent defectors among residents who escaped from North Korean (adolescent defectors, n=423) and adolescents with South Korean...
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Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning

Lee CH, Jo DJ, Oh JK, Hyun SJ, Park JH, Kim KH, Bae JS, Moon BJ, Lee CK, Shin MH, Jang HJ, Han MS, Kim CH, Chung CK, Moon SM, for the Korean Spinal Deformity Society

Objective: Although adult spinal deformity (ASD) surgery aims to restore and maintain alignment, proximal junctional kyphosis (PJK) may occur. While existing scoring systems predict PJK, they predominantly offer a generalized...
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The Combined Effects of RhBMP-2 and Systemic RANKL Inhibitor in Patients With Bone Density Loss Undergoing Posterior Lumbar Interbody Fusion: A Retrospective Observational Analysis With Propensity Score Matching

Ryu S, Yoon SJ, Lee CK, Yi S, Kim KN, Ha Y, Shin DA

Objective: The risks of nonunion and subsidence are high in patients with bone density loss undergoing spinal fusion surgery. The internal application of recombinant human bone morphogenic protein 2 (rhBMP-2)...
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Diagnostic Challenges of Rosai-Dorfman Disease Presenting as Pachymeningitis and Meningiomatosis: A Report of Two Unusual Cases Involving the Spinal Cord

Park JH, Lee CK, Kim SH, Chang JH, Shin DA, Yi S, Ha Y, Kim KN

Rosai-Dorfman disease (RDD) is an exceptionally rare medical condition, with spinal cord involvement even more infrequent. It is frequently misidentified as another malignancy or infectious disease. In this report, we...
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Clinicopathological Characteristics of NRG1 Fusion–Positive Solid Tumors in Korean Patients

Cha YJ, Lee C, Joo B, Kim KA, Lee Ck, Shim HS

Purpose Neuregulin 1 (NRG1) gene fusion is a potentially actionable oncogenic driver. The oncoprotein binds to ERBB3-ERBB2 heterodimers and activates downstream signaling, supporting a therapeutic approach for inhibiting ERBB3/ERBB2. However,...
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ARID1A Mutation from Targeted Next-Generation Sequencing Predicts Primary Resistance to Gemcitabine and Cisplatin Chemotherapy in Advanced Biliary Tract Cancer

Lee SH, Cheon J, Lee S, Kang B, Kim C, Shim HS, Park YN, Jung S, Choi SH, Choi HJ, Lee Ck, Chon HJ

Purpose There are clinical unmet needs in predicting therapeutic response and precise strategy for the patient with advanced biliary tract cancer (BTC). We aimed to identify genomic alterations predicting therapeutic...
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Three-Dimensional Quantitative Assessment of Pedicle Screw Accuracy in Clinical Utilization of a New Robotic System in Spine Surgery: A Multicenter Study

Ha BJ, Lee JM, Yoon SJ, Kim BK, Lee J, Lee S, Ryu S, Cha Y, Hwang S, Woo D, Lee CK, Shin DA, Ha Y, Kuh SU, Kim KN, Son D, Yi S

Objective: The objective of this study was to evaluate the accuracy of pedicle screw placement in patients undergoing percutaneous pedicle screw fixation with robotic guidance, using a newly developed 3-dimensional...
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Monitoring the Outcomes of Systemic Chemotherapy Including Immune Checkpoint Inhibitor for HER2-Positive Metastatic Gastric Cancer by Liquid Biopsy

Jung SH, Lee Ck, Kwon WS, Yun S, Jung M, Kim HS, Chung HC, Chung YJ, Rha SY

Purpose: For precision medicine, exploration and monitoring of molecular biomarkers are essential. However, in advanced gastric cancer (GC) with visceral lesions, an invasive procedure cannot be performed repeatedly for the...
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Long-term renal outcomes of patients with non-proliferative lupus nephritis

Kang ES, Ahn SM, Oh JS, Kim YG, Lee CK, Yoo B, Hong S

Background/Aims: Although non-proliferative lupus nephritis (LN) (class I, II or V) has been considered as a less severe type of LN, data on long-term renal prognosis are limited. We investigated...
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Real-world effectiveness and safety of adalimumab in Korean patients with intestinal Behcet’s disease: a Korean Association for the Study of Intestinal Diseases (KASID) multicenter study

Lee SB, Hong HS, Lee CK, Lee BI, Kim S, Koh SJ, Yu H, Park JB, Hwang SW, Ye BD, Yang SK, Park SH, on behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)

Background/Aims: The short- and long-term effects of adalimumab (ADA) on Korean patients with intestinal Behcet’s disease (BD) for remain unclear. Therefore, a multicenter study was performed to evaluate the efficacy...
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Factors influencing fall in the community-dwelling elderly: Data from the 2020 national survey of older people: A secondary analysis study

Lee CK

Purpose: This study was performed to identify the factors influencing fall in the community-dwelling elderly using the raw data of the 2020 national older Koreans data. Methods: The study included...
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A Novel Trajectory of C7 Laminar Screws Determined Using Three-Dimensional Computed Tomography and Surgical Simulation Software: Comparison with a Pre-existing Trajectory

Lee CK, Li QY, Park J, Park SM, Kim HJ, Chang BS, Woo B, Yeom JS

Study Design: Examination using three-dimensional screw trajectory software and computed tomographic scans. Purpose: To evaluate the feasibility of a novel trajectory for C7 laminar screws and to compare it with an...
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COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants

Padasas BT, Españo E, Kim SH, Song Y, Lee CK, Kim JK

The coronavirus disease 2019 (COVID-19) pandemic is one of the most consequential global health crises in over a century. Since its discovery in 2019, severe acute respiratory syndrome coronavirus 2...
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Anti-S1/RBD-Specific Antibody Formation After SARS-CoV-2 Vaccination in Elderly Rheumatoid Arthritis Patients: Single-Center Prospective Observational Study

Kang ES, Oh JS, Lee EJ, Hong S, Ahn SM, Lee CK, Yoo B, Kim YG

Background: The guidelines of coronavirus disease 2019 (COVID-19) vaccination in patients with rheumatoid arthritis (RA) have been continuously updated, with extensive discussion on the effectiveness of the COVID-19 booster vaccines...
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The Use of High-Density Pedicle Screw Construct with Direct Vertebral Derotation of the Lowest Instrumented Vertebra in Selective Thoracic Fusion for Adolescent Idiopathic Scoliosis: Comparison of Two Surgical Strategies

Chang SY, Kim JH, Mok S, Chang BS, Lee CK, Kim H

Study Design: This study was a retrospective case series. Purpose: This study was designed to determine whether direct vertebral rotation (DVR) of the lowest instrumented vertebra (LIV) using a high-density (HD)...
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Biportal Endoscopic Posterior Thoracic Laminectomy for Thoracic Spondylotic Myelopathy Caused by Ossification of the Ligamentum Flavum: Technical Developments and Outcomes

Kim JY, Ha JS, Lee CK, Lee DC, Hong HJ, Choi SY, Park CK

Objective: Advanced biportal endoscopic surgery techniques can be used to treat thoracic myelopathy secondary to ossification of the ligamentum flavum (OLF). This case series elaborates on a feasible biportal endoscopic...
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Incidence of rheumatic diseases during the COVID-19 pandemic in South Korea

Ahn SM, Eun S, Ji S, Hong S, Lee CK, Yoo B, Oh JS, Kim YG

Background/Aims: The recent coronavirus disease 2019 (COVID-19) pandemic has been associated with changes in the epidemiology of not only infectious diseases but also several non-infectious conditions. This study investigated changes...
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Korean clinical practice guidelines on biologics and small molecules for moderate-to-severe ulcerative colitis

Na SY, Choi CH, Song EM, Bang KB, Park SH, Kim ES, Park JJ, Keum B, Lee CK, Lee BI, Ryoo SB, Koh SJ, Choi M, Kim JS, On behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases

Ulcerative colitis (UC), a relapsing-remitting chronic inflammatory bowel disease (IBD), has a variable natural course but potentially severe disease course. Since the development of anti-tumor necrosis factor (TNF) agents has...
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Reconstruction of Severe Burn Scar Deformities on the Distal Nose and Philtrum

Kim JH, Chung CE, Lee CK, Kim DC

Severe facial burns on the peaking portion of the face, such as the nose, and the central facial structure, such as the upper lip, significantly result in ugly facial features....
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Large Lower Lip Defect Reconstruction Using a Karapandzic Flap: A Case Report and Literature Review

Kim JH, Chung CE, Lee CK

Squamous cell carcinoma is the most common cancer occurring in the oral cavity and oncologic wide cancer excision is a major cause of large lip defects. Large lower lip defect...
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