Ann Dermatol.  2013 Nov;25(4):440-444. 10.5021/ad.2013.25.4.440.

An Observational Study on the Obesity and Metabolic Status of Psoriasis Patients

• Kim CR
• Lee JH

• KMID: 2265053
• DOI: http://doi.org/10.5021/ad.2013.25.4.440

Abstract

BACKGROUND
Recent studies have suggested that obesity, hyperlipidemia, ischemic heart diseases, metabolic syndrome and hypertension can combine with psoriasis. However, the metabolic comorbidities have not been clearly demonstrated in Korean psoriasis patients.
OBJECTIVE
The purpose of this study was to analyze the association between psoriasis and metabolic abnormalities including obesity, glucose intolerance, hypertension and dyslipidemia in our center. Treatment response of cyclosporine between a high body mass index (BMI) group and normal BMI group was also analyzed to investigate how obesity may affect psoriasis treatment.
METHODS
A retrospective observational study was made on the obesity and metabolic status of psoriasis patients versus normal control group through electronic medical records from January 2008 to April 2009 at Department of Dermatology, Samsung Medical Center, (Seoul, Korea). Medical records, demographics and the Psoriasis Area and Severity Index score before and after cyclosporine treatment were analyzed.
RESULTS
There were no significant differences in the metabolic status between normal control and psoriasis patients. Also, there was no significant difference in the treatment response between high BMI group and normal BMI group, after 4 weeks and 8 weeks of cyclosporine treatment.
CONCLUSION
Our study suggests that in Korean patients, an association between psoriasis and metabolic abnormalities is not obvious. This may reflect a different severity of obesity and metabolic abnormalities between Western and Asian populations.

Keyword

Metabolic syndrome; Obesity; Psoriasis

MeSH Terms

Asian Continental Ancestry Group
Body Mass Index
Comorbidity
Cyclosporine
Demography
Dermatology
Dyslipidemias
Electronic Health Records
Glucose Intolerance
Humans
Hyperlipidemias
Hypertension
Medical Records
Myocardial Ischemia
Obesity*
Psoriasis*
Retrospective Studies
Cyclosporine

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