Korean J Gastrointest Endosc.  1998 Dec;18(6):922-929.

A Case of Hodgkin's Disease Involved in the Stomach and Terminal Ileum

Affiliations
  • 1Department of Internal Medicine, Wallace Memorial Baptist Hospital, Pusan, Korea.
  • 2Department of Anatomical Pathology, Wallace Memorial Baptist Hospital, Pusan, Korea.

Abstract

Cases with extranodal Hodgkin's disease located in sites outside those defined as lymphatic structure are quite rare. The exact incidence of this localized form of Hodgkin's disease is unknown, but it is estimated to be only 0.25% for overall incidence of Hodgkin's disease. Localized primary extranodal Hodgkin's disease seems to have an excellent prognosis in some cases including skin, tongue, lung, stomach, small bowel, and thyroid. We report a case of primary gastrointestinal Hodgkin's disease involved in the stomach and terminal ileum in 48-year-old man with 7 kg of weight loss for 3 months, fever with chills for 1 week, and intermittent epigastric pain for 1 year. The histologic type of this case was lymphocyte predominance, which was diagnosed by biopsy of the stomach and terminal ileum with immnophenotyping study. And the stage of this case was IIE. We tried combination chemotherapy with adriamycin, bleomycin, vinblastin, and dacabazine with excellent response. For its rarity, we report this case with review of literatures.

Keyword

Malignant lymphoma; Hodgkin's disease; Stomach; Terminal ileum

MeSH Terms

Biopsy
Bleomycin
Chills
Doxorubicin
Drug Therapy, Combination
Fever
Hodgkin Disease*
Humans
Ileum*
Incidence
Lung
Lymphocytes
Lymphoma
Middle Aged
Prognosis
Skin
Stomach*
Thyroid Gland
Tongue
Weight Loss
Bleomycin
Doxorubicin
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