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Anaplastic Transformation of Metastatic Papillary Thyroid Carcinoma in a Cervical Lymph Node: a Timeline and Short Review

Cinamon U, Horev Y, Vaknine H

Anaplastic thyroid cancer (ATC) is accepted as the transformation of a pre-existing glandular papillary thyroid carcinoma (PTC). Anaplastic transformation of a neck PTC metastasis in a lymph node is extraordinary....
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Author's Response: A Prospective, Randomized, Controlled Comparative Study of Three Energy Devices in Open Thyroid Surgery: Thunderbeat, Harmonic, and Ligasure

Kim JS

No abstract available.
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Letter to the Editor: A Prospective, Randomized, Controlled Comparative Study of Three Energy Devices in Open Thyroid Surgery: Thunderbeat, Harmonic, and Ligasure

Mayilvaganan S, Vnssvams M

No abstract available.
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Acquired Strabismus and Diplopia as Initial Presentation Signs of Hyperthyroidism and Thyroid Eye Disease

Chung SM, Kim WJ

PURPOSE: We evaluated the clinical characteristics of patients who recently acquired strabismus and diplopia as the initial presentations of hyperthyroidism and thyroid eye disease (TED). METHODS: The medical records of patients...
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Determination of maternal risk factors of preterm delivery: adjusted for sparse data bias; results from a population-based case-control study in Iran

Valipour M, Ayubi E, Shiravand , Moradi Y, Abbaszadeh A, Amrai F, Mokhtari S, Bahmanpour K, Mansori K

OBJECTIVE: To determine the maternal risk factors associated with preterm delivery in Iran. METHODS: A population-based case-control study was conducted including 48 women having preterm delivery (case group) and 100 women...
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Modification of the Tumor-Node-Metastasis Staging System for Differentiated Thyroid Carcinoma by Considering Extra-Thyroidal Extension and Lateral Cervical Lymph Node Metastasis

Kim M, Kim WG, Jeon MJ, Kim HK, Yi HS, Kim ES, Kim BH, Kim WB, Shong YK, Kang HC, Kim TY

BACKGROUND: Concerns have arisen about the classification of extra-thyroidal extension (ETE) and lateral cervical lymph node metastasis (N1b) in the 8th edition of the tumor-node-metastasis staging system (TNM-8). This study...
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Quality of Life in Patients with Papillary Thyroid Microcarcinoma According to Treatment: Total Thyroidectomy with or without Radioactive Iodine Ablation

Ahn J, Jeon MJ, Song E, Kim TY, Kim WB, Shong YK, Kim WG

BACKGROUND: Recently, there has been some controversy regarding the role of radioactive iodine (RAI) ablation in the treatment of low-risk differentiated thyroid carcinoma (DTC), especially papillary thyroid microcarcinoma (PTMC). This...
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Association between Serum Free Thyroxine and Anemia in Euthyroid Adults: A Nationwide Study

Kim M, Kim BH, Lee H, Jang MH, Kim JM, Kim EH, Jeon YK, Kim SS, Kim IJ

BACKGROUND: Studies on the relationship between thyroid function and anemia in the euthyroid range are scarce. We aimed to evaluate the association between anemia and serum free thyroxine (fT4) and...
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Machine Learning Applications in Endocrinology and Metabolism Research: An Overview

Hong N, Park H, Rhee Y

Machine learning (ML) applications have received extensive attention in endocrinology research during the last decade. This review summarizes the basic concepts of ML and certain research topics in endocrinology and...
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Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers

Yoo SK, Song YS, Park YJ, Seo JS

Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5...
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Unmet Clinical Needs in the Treatment of Patients with Thyroid Cancer

Kim WB, Jeon MJ, Kim WG, Kim TY, Shong YK

The increased incidence of thyroid cancer is a worldwide phenomenon; however, the issue of overdiagnosis has been most prominent in South Korea. The age-standardized mortality rate of thyroid cancer in...
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Update on Thyroid Hormone Levels and Thyroid Dysfunction in the Korean Population Based on Data from the Korea National Health and Nutrition Examination Survey VI (2013 to 2015)

Chung JH

In 2017, the first Korean nationwide data on serum thyroid stimulating hormone (TSH) levels, serum free thyroxine (fT4) levels, and urinary iodine concentration (UIC) were published based on a population...
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Separate thyrothymic thyroid remnant; clinically crucial anatomic variation

Gurleyik E, Gurleyik G

PURPOSE: The anatomical variations of the thyroid gland including separate thyroidal remnant at the thyrothymic area are of significance during thyroid surgery for “total” thyroidectomy, and for recurrent goitre. In...
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Feasibility of Adjustable Electrodes for Radiofrequency Ablation of Benign Thyroid Nodules

Lee J, Shin JH, Hahn SY, Park KW, Choi JS

OBJECTIVE: The purpose of this study was to evaluate a novel radiofrequency ablation (RFA) application utilizing an adjustable electrode for treatment of benign thyroid nodules. MATERIALS AND METHODS: From April 2011...
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Computer-Aided Diagnosis System for the Evaluation of Thyroid Nodules on Ultrasonography: Prospective Non-Inferiority Study according to the Experience Level of Radiologists

Chung SR, Baek JH, Lee MK, Ahn Y, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

OBJECTIVE: To determine whether a computer-aided diagnosis (CAD) system for the evaluation of thyroid nodules is non-inferior to radiologists with different levels of experience. MATERIALS AND METHODS: Patients with thyroid nodules...
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Ultrasonographic Demonstration of the Tissue Microvasculature in Children: Microvascular Ultrasonography Versus Conventional Color Doppler Ultrasonography

Yoo J, Je BK, Choo JY

Microvascular ultrasonographic imaging is the most recent and unique Doppler ultrasound technique. It uses an advanced clutter filter that can remove clutter artifacts and preserve the low-velocity microvascular flow signal....
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Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors

Choi J, Lee SY

Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment. However, immune-related adverse effects (irAEs) have also increased with the exponential increase in the use of ICIs. ICIs...
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Core-Needle Biopsy Does Not Show Superior Diagnostic Performance to Fine-Needle Aspiration for Diagnosing Thyroid Nodules

Shin I, Kim EK, Moon HJ, Yoon JH, Park VY, Lee SE, Lee HS, Kwak JY

PURPOSE: To compare the diagnostic performances of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for thyroid nodules according to nodule size. MATERIALS AND METHODS: This retrospective study included 320 thyroid nodules...
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Concordance of Three International Guidelines for Thyroid Nodules Classified by Ultrasonography and Diagnostic Performance of Biopsy Criteria

Yim Y, Na DG, Ha EJ, Baek JH, Sung JY, Kim JH, Moon WJ

OBJECTIVE: To investigate the concordance of three international guidelines: the Korean Thyroid Association/Korean Society of Thyroid Radiology, American Thyroid Association, and American College of Radiology for thyroid nodules classified by...
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Congenital hypothyroidism due to thyroglobulin deficiency: a case report with a novel mutation in TG gene

Heo S, Jang JH, Yu J

Congenital hypothyroidism (CH) is the most common endocrine disorder in neonates and infants with an incidence of one in 2,000 to one in 4,000 newborns. Primary CH can be caused...
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