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Lymphoproliferative disorder involving body fluid: diagnostic approaches and roles of ancillary studies

Koh J, Shin SA, Lee JA, Jeon YK

Lymphocyte-rich effusions represent benign reactive process or neoplastic condition. Involvement of lymphoproliferative disease in body cavity is not uncommon, and it often causes diagnostic challenge. In this review, we suggest...
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Clinicopathologic implication of PD-L1 gene alteration in primary adrenal diffuse large B cell lymphoma

Lee KR, Koh J, Jeon YK, Kwon HJ, Lee JO, Paik JH

Background: Primary adrenal (PA) diffuse large B cell lymphoma (DLBCL) was previously reported as an aggressive subset of DLBCL, but its genetic features were not sufficiently characterized. From our previous...
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Morphologic variant of follicular lymphoma reminiscent of hyaline-vascular Castleman disease

Koh J, Jeon YK

Follicular lymphoma (FL) with hyaline-vascular Castleman disease (FL-HVCD)-like features is a rare morphologic variant, with fewer than 20 cases in the literature. Herein, we report a case of FL-HVCD in...
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Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives

Jeon YK, Yoon SO, Paik JH, Kim YA, Shin BK, Kim HJ, Cha HJ, Kim JE, Huh J, Ko YH, The Hematopathology Study Group of the Korean Society of Pathologists, The Molecular Pathology Study Group of Korean Society of Pathologists

Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative...
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A Case of Pediatric Nodal Marginal Zone Lymphoma

Min B, Youn JK, Han JW, Oh C, Kim HY, Jung SE

Lymph node enlargement is a common finding in children suggesting normal or benign. Palpable nodes which are large, hard or fixed must be examined carefully to rule out malignant diseases....
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Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids with a Significant Elevation of beta-2 Microglobulin Levels

Fujisawa N, Oya S, Mori H, Matsui T

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a relapsing-remitting disorder for which steroid administration is a key to control the progression. CLIPPERS can exhibit radiological...
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Clinical Analysis of Primary Conjunctival Malignant Lymphoma

Yang JM, Lee JJ, Yoon KC

PURPOSE: To investigate clinical outcomes, response to treatment, and the related factors of recurrence and complication, following treatment of primary conjunctival malignant lymphoma. METHODS: The medical records of 39 patients diagnosed...
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Effects of oral iron chelator deferasirox on human malignant lymphoma cells

Choi JG, Kim JL, Park J, Lee S, Park SJ, Kim JS, Choi CW

BACKGROUND: Iron is essential for cell proliferation and viability. It has been reported that iron depletion by a chelator inhibits proliferation of some cancer cells. Deferasirox is a new oral...
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Epidemiologic overview of malignant lymphoma

Huh J

Malignant lymphoma encompasses a wide variety of distinct disease entities. It is generally more common in developed countries and less common in developing countries. The East Asia region has one...
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Cellular Density Evaluation for Malignant Lymphoma Using Equivalent Cross-Relaxation Rate Imaging - Initial Experience

Nishiofuku H, Matsushima S, Inaba Y, Yamaura H, Sato Y, Morishima , Kichikawa

OBJECTIVE: Equivalent cross-relaxation rate (ECR) imaging is an MRI technique used to evaluate quantitatively a change in the protein-water interaction. We aimed to evaluate retrospectively the usefulness of ECR imaging...
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Two cases of primary malignant lymphoma of the uterine cervix

Lim SO, Key EY, Ro DY, Park BJ, Kim YW, Kim TE, Jung JK, Han CW, Lee AH

  • KMID: 2273786
  • Korean J Obstet Gynecol.
  • 2009 Oct;52(10):1051-1055.
Primary malignant lymphoma of the uterine cervix is very rare. Lymphomas account for 3.5% of all malignant tumors in the females. Approximately, 25% of all malignant lymphomas arise from extranodal...
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A Case of Orbital Malignant Lymphoma associated with Acquired Immunodeficiency Syndrome (AIDS)

Kim SJ, Shin MG, Lee JS

  • KMID: 2337674
  • J Korean Ophthalmol Soc.
  • 2008 Sep;49(9):1543-1547.
PURPOSE: To report a rare case of orbital malignant lymphoma that occurred in a patient with acquired immunodeficiency syndrome. CASE SUMMARY: A 39-year-old male with acquired immunodeficiency syndrome complained of proptosis...
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Incidence and Histologic Patterns of Bone Marrow Involvement of Malignant Lymphoma Based on the World Health Organization Classification: A Single Institution Study

Jeong SY, Chang YH, Lee JK, Hong YJ, Hong SI, Lee SS

BACKGROUND: Working Formulation and Revised European American Classification of Lymphoid Neoplasms (REAL) have mainly been used in the studies for bone marrow involvement of malignant lymphoma in Korea. We...
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The clinicopathologic features of six cases of primary malignant cervical lymphoma

Kong KY, Kwon YS, Choi GW, Han AR, Ahn JW, Yoo HJ, Kim YM, Kim YT, Nam JH

  • KMID: 1926281
  • Korean J Obstet Gynecol.
  • 2007 Nov;50(11):1485-1492.
OBJECTIVE: To provide clinical information for the best diagnosis and treatment of primary malignant cervical lymphoma based on the information obtained from these cases. METHODS: Between 1989 and 2006, six women...
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The Clinical Role of FDG PET in Malignant Lymphoma

Cheon GJ

  • KMID: 1893646
  • Hanyang Med Rev.
  • 2007 Nov;27(4):66-75.
FDG PET is a functional and metabolic imaging modality to detect lesions with altered glycolytic activity. Conventional imaging modalities, such as CT or MRI, provide tissue information based on anatomical...
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The Expression of p16 in Diffuse Large B-cell Lymphoma and Its Prognostic Implications

Kim DH, Sohn JH, Kim MK, Lee KB, Kang SH, Chae SW

BACKGROUND: The molecular mechanisms that are responsible for the initiation and progression of diffuse large B-cell lymphoma are largely unknown. p16 is an inhibitor of cyclin-dependent kinase and its inactivation...
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A Case of Esophageal T-cell Lymphoma Presenting as Multiple Discrete Ulcers on a Background of Normal Mucosa

Lee SB, Park SJ, Jee SR, Park ET, Lee YJ, Lee SH, Seol SY, Kang SW, Park JH, Pae KI

  • KMID: 2304820
  • Korean J Gastrointest Endosc.
  • 2007 Jan;34(1):28-32.
Gastrointestinal involvement by a lymphoma occurs in 20% of patients with a lymphoma and frequently involves the stomach, small bowel or colon, but rarely involves the esophagus. Esophageal lymphomas are...
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A Case of Dual Malignancy in a Renal Transplanted Recipient

Lee SY, Bin HG, Kim JA, Lee SJ, Chang YK, Lee HK, Kim SY, Chang YS, Bang BK

  • KMID: 2079644
  • Korean J Nephrol.
  • 2006 May;25(3):507-514.
Kidney transplantation is a ideal renal replacement therapy in the patient with end stage renal disease. It made improvement of the patients' life quality but made increase of the incidence...
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Malignant lymphoma originated from uterine cervix and extended to endometrium: A case report

Lee WM, Lee JE, Hwang JH

  • KMID: 2143543
  • Korean J Gynecol Oncol.
  • 2005 Dec;16(4):361-365.
Primary malignant lymphoma arising from the female genital tract is extremely rare. Most genital lymphomas arise in the Corpus and cervix of uterus and vagina. Patients usually present with bleeding,...
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Ovarian Involvement of Peripheral T-Cell Lymphoma as Initial Manifestation of Extranodal Disease

Shin SS, Jeong YY, Song SG, Kang HK

We report here on a case of peripheral T-cell lymphoma of the ovary as the initial manifestation of extranodal disease. A 45-year-old woman presented with an incidentally detected, ovarian mass....
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