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Trend of Disease Burden of North Korean Defectors in South Korea Using Disability-adjusted Life Years from 2010 to 2018

Kim KA, Jung YS, Kim CB, Kim KB, Yoon SJ

Background: This study aimed to examine the disease burden of North Korean defectors in South Korea by sex, age, and disease from 2000 to 2018 and to study the changes...
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Validation of the Simplified Palliative Prognostic Index to Predict Survival for Advanced Cancer Patients in Home Hospice Setting

Yang HJ, Yoon SJ, Kim JS, Kim SS, Jung JG, Suh WY, Lee S, Kim HG, Lee YW

Background: The simplified Palliative Prognostic Index (sPPI) substitutes a single item from the Communication Capacity Scale (CCS) for the delirium item of the original PPI. This study aimed to examine...
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Discontinuation Rate of Newly Prescribed Donepezil in Alzheimer’s Disease Patients in Asia

Park KH, Yang Y, Chen C, Shim YS, Dominguez JC, Lee CN, Kang K, Kim HJ, Jeong SK, Jeong JH, Hong Z, Yoon SJ, Zhang ZX, Kim EJ, Jang JW, Li Y, Xu Y, Lin YT, Qu Q, Hu CJ, Chou CH, Fan D, Kandiah N, Yang YH, Lau Ci, Chu LW, Wang H, Jung S, Choi SH, Kim S

Background and Purpose The rate of donepezil discontinuation and the underlying reasons for discontinuation in Asian patients with Alzheimer’s disease (AD) are currently unknown. We aimed to determine the treatment...
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Impact of an Education Program for Caregivers of Patients with Alzheimer’s Disease on Treatment Discontinuation and Compliance in Korea

Kim HJ, Shim YS, Park KH, Lee CN, Jung S, Yoon SJ, Jeong SK, Jeong JH, Choi SH, Kim EJ, Jang JW, Kang K, Yang Y, Kim S

Background and Purpose: Reportedly 30–50% of patients being treated for chronic illnesses do not adhere to their medication regimen. We assessed the impact of a nurse-led education program for caregivers...
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Risk Factors of Outcomes of COVID-19 Patients in Korea: Focus on Early Symptoms

Jang SY, Seon JY, Eun BL, Koh SB, Yoo JH, Lee WY, Yum HK, Yoon SJ, Oh IH, Bae SC, Chang SG

Background: Coronavirus disease 2019 (COVID-19) has spread around the globe, and it is important to determine the risk factors of death in the general population. Our study aimed to determine...
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Malignancy Risk Stratification of Thyroid Nodules with Macrocalcification and Rim Calcification Based on Ultrasound Patterns

Shin HS, Na DG, Paik W, Yoon SJ, Gwon HY, Noh BJ, Kim WJ

Objective: To determine the association of macrocalcification and rim calcification with malignancy and to stratify the malignancy risk of thyroid nodules with macrocalcification and rim calcification based on ultrasound (US)...
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Korean Alcohol Guidelines for Primary Care Physician

Jung JG, Kim JS, Yoon SJ, Lee S, Ahn SK

Patients with drinking problems are commonly encountered by primary care physicians in clinical practice. This paper presents the care guidelines for dealing with such patients. The guidelines have been summarized...
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Influence of the Amount of Fresh Specimen on the Isolation of Tumor Mesenchymal Stem-Like Cells from High-Grade Glioma

Kong SH, Yoo J, Lee D, Moon S, Sung KS, Park SH, Shim JK, Choi RJ, Yoon SJ, Moon JH, Kim EH, Lee SJ, Chang JH, Kang SG

Purpose: A critical indicator of the overall survival of patients with high-grade glioma is the successful isolation of tumor mesenchymal stem-like cells (tMSLCs), which play important roles in glioma progression....
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Lactobacillus attenuates progression of nonalcoholic fatty liver disease by lowering cholesterol and steatosis

Lee NY, Shin MJ, Youn GS, Yoon SJ, Choi YR, Kim HS, Gupta H, Han SH, Kim BK, Lee DY, Park TS, Sung H, Kim BY, Suk KT

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is closely related to gut-microbiome. There is a paucity of research on which strains of gut microbiota affect the progression of NAFLD. This study...
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Association between Alcohol Consumption and Metabolic Syndrome Determined by Facial Flushing in Korean Women

Seo YR, Kim JS, Kim SS, Jung JG, Yoon SJ

Background: This study aimed to examine the relationship between alcohol consumption and metabolic syndrome in Korean women as determined by facial flushing. Methods: Of the female patients aged 4 standard drinks...
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Current Status and Reform Tasks in Life Cycle Management of Korean Health Technology for the Fourth Industrial Revolution Era

Kim A, Kim EJ, Yoon SJ

Entering the fourth industrial revolution era, health technology is rapidly developing and the people's needs for medical services are gradually increasing. Establishing a life cycle management of health technology has...
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Clinical Outcomes of Total Hip Arthroplasty for Displaced Femoral Neck Fractures in Patients 80 Years of Age and Older Selected by Clinical Frailty Score

Jo S, Lee SH, Yoon SJ

Purpose: The utility of total hip arthroplasty (THA) for the treatment of displaced femoral neck fractures in elderly patients (≥80 years of age) remains controversial as a patient’s general condition...
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Laparoscopic Hiatal Hernia Repair and Roux-en-Y Conversion for Refractory Duodenogastroesophageal Reflux after Billroth I Distal Gastrectomy

Park JM, Yoon SJ, Kim JW, Chi KC

Distal gastrectomy with Billroth I or II reconstruction may cause duodenogastroesophageal reflux (DGER), thereby resulting in digestive or respiratory symptoms. The mainstay of treatment is medication with proton pump inhibitors....
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Years of Life Lost Attributable to COVID-19 in High-incidence Countries

Oh IH, Ock M, Jang SY, Go DS, Kim YE, Jung YS, Kim KB, Park H, Jo MW, Yoon SJ

Background: The coronavirus disease 2019 (COVID-19) pandemic is a major public health problem of international concern. It is important to estimate its impact of COVID-19 for health policy decision-making. We...
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Pulmonary Surfactant Replacement Therapy for Respiratory Distress Syndrome in Neonates: a Nationwide Epidemiological Study in Korea

Shin JE, Yoon SJ, Lim J, Han J, Eun HS, Park MS, Park KI, Lee SM

Background: Pulmonary surfactant (PS) replacement therapy, as a safe and effective treatment for respiratory distress syndrome (RDS) may have further increased with the extended insurance coverage since 2011 in Korea....
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Updating Disability Weights for Measurement of Healthy Life Expectancy and Disability-adjusted Life Year in Korea

Kim YE, Jo MW, Park H, Oh IH, Yoon SJ, Pyo J, Ock M

Background: The present study aimed to update the methodology to estimate cause-specific disability weight (DW) for the calculation of disability adjusted life year (DALY) and health-adjusted life expectancy (HALE) based...
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Establishment of a Maximum Surgical Blood Order Schedule and Red Blood Cell Mean Transfusion Units Per Patient According to Adjacent Diagnosis Related Groups Patient Classification System

Yoon SJ, Lee K, Kwon MJ, Park H, Woo HY

Background: For effective management of blood components, periodic updates of the maximum surgical blood order schedule (MSBOS) using recent data are crucial. This study aimed to establish an updated MSBOS...
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Socioeconomic Burden of Cancer in Korea from 2011 to 2015

Kim YA, Lee YR, Park J, Oh IH, Kim H, Yoon SJ, Park K

Purpose Though the socioeconomic burden of cancer on patients is increasing in South Korea, there is little research regarding the type of cancer that incurs the highest costs. This study analyzed...
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Backpack Palsy Presenting as a First Manifestation of Hereditary Neuropathy with Liability to Pressure Palsy

Yoon HS, Yoon SJ, Kim NH

A 21-year-old soldier was admitted due to weakness after carrying a heavy military bag and marching for a long time. Neurophysiologic investigation revealed prominent involvement of right brachial plexus and...
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The Burden of Disease due to COVID-19 in Korea Using Disability-Adjusted Life Years

Jo MW, Go DS, Kim R, Lee SW, Ock M, Kim YE, Oh IH, Yoon SJ, Park H

Background: The world is currently experiencing a pandemic of coronavirus disease 2019 (COVID-19). In Korea, as in other countries, the number of confirmed cases and deaths due to COVID-19 have...
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