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Development of an Automated Image Analyzer for Microvessel Density Measurement in Bone Marrow Biopsies

Chung Y, Shin S, Shim H, Sohn JY, Lee DE, Lee H, Eom HS, Kim KG, Kong SY

Angiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and an increase in MVD...
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Comparison of Exercise Performance and Clinical Outcome Between Functional Complete and Incomplete Revascularization

Kim J, Lee JM, Choi SH, Choi KH, Park TK, Park SJ, Yang JH, Song YB, Hahn JY, Jang MJ, Koo BK, Gwon HC

BACKGROUND AND OBJECTIVES: Although percutaneous coronary intervention (PCI) is recommended to improve symptoms in patients with stable ischemic heart disease (SIHD), improvement of exercise performance is controversial. This study aimed...
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Clinical, Laboratory, and Bone Marrow Findings of 31 Patients With Waldenström Macroglobulinemia

Ahn A, Park CJ, Cho YU, Jang S, Seo EJ, Lee JH, Yoon DH, Suh C

BACKGROUND: Waldenström macroglobulinemia (WM) is a subset of lymphoplasmacytic lymphoma (LPL) with bone marrow (BM) involvement and an IgM monoclonal gammopathy of any level. We aimed to identify the clinical,...
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Protocol of a Nationwide Observational Study among Patients with Nontuberculous Mycobacterium Pulmonary Disease in South Korea (NTM-KOREA)

Kwak N, Choi H, Jeon D, Jhun BW, Jo KW, Kang YA, Kwon YS, Lee M, Mok J, Shim TS, Shin HJ, Whang J, Yim JJ

BACKGROUND: The burden of nontuberculous mycobacterial (NTM) pulmonary disease (PD) is increasing globally. To understand the treatment outcomes and prognosis of NTM-PD, a unified registry is needed. In this project,...
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Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia

Tasaka S

In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia (PCP) is a wellk-nown opportunistic infection and its management has been established. However, PCP is an emerging threat to immunocompromised patients...
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Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway

Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W

BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found...
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HIV-negative plasmablastic lymphoma: report of 8 cases and a comprehensive review of 394 published cases

Li YJ, Li JW, Chen KL, Li J, Zhong MZ, Liu XL, Yi PY, Zhou H

BACKGROUND: Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma (PBL) is a rare entity of diffuse large B-cell lymphoma (DLBCL). The clinicopathological features of and optimal treatment for HIV-negative PBL remain largely...
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Association between Lymphovascular Invasion and Recurrence in Patients with pT1N+ or pT2–3N0 Gastric Cancer: a Multi-institutional Dataset Analysis

Fujita K, Kanda M, Ito S, Mochizuki , Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi , Fujiwara M, Murotani K, Kodera Y

PURPOSE: Patients with pathological stage T1N+ or T2–3N0 gastric cancer may experience disease recurrence following curative gastrectomy. However, the current Japanese Gastric Cancer Treatment Guidelines do not recommend postoperative adjuvant...
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Advantages of Splenic Hilar Lymph Node Dissection in Proximal Gastric Cancer Surgery

Guner A, Hyung WJ

Gastrectomy with lymph node dissection remains the gold standard for curative treatment of gastric cancer. Dissection of splenic hilar lymph nodes has been included as a part of D2 lymph...
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Phlegmonous Gastritis Caused by Penetration of a Toothpick

Rim CB, Kim SM

Phlegmonous gastritis is a disease caused by a bacterial infection of the gastric wall. This condition is rare, but when it does occur, its prognosis appears to be poor. The...
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Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis

Kang HR, Choi SM

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough...
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Case Report of Nodular Fasciitis in the Conjunctiva

Kim JH, Na KS, Park CH, Lee SJ, Oh TH, Kim HS

PURPOSE: We report a case of nodular fasciitis of the conjunctiva that has not been previously reported in the Republic of Korea. CASE SUMMARY: A 18-year-old female patient presented with a...
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Visual Prognosis and Satisfaction of Advanced Cataract Patients Unable to be Evaluated by Fundus Imaging

You JI, Bang SK, Kang MS, Jin KH

PURPOSE: We evaluated the surgical prognoses of patients with advanced cataract who were unable to be evaluated by fundus imaging and their satisfaction with daily life. METHODS: We retrospectively reviewed 748...
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Epidemiology and Prognosis of Pheochromocytoma/Paraganglioma in Korea: A Nationwide Study Based on the National Health Insurance Service

Kim JH, Moon H, Noh J, Lee J, Kim SG

BACKGROUND: Pheochromocytomas and paragangliomas (PPGLs) are rare endocrine tumors originating from chromaffin cells. PPGLs are associated with a high mortality rate and several complications. To date, no epidemiological studies have...
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Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma

Moon SJ, Kim JH, Kong SH, Shin CS

BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been...
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Unmet Clinical Needs in the Treatment of Patients with Thyroid Cancer

Kim WB, Jeon MJ, Kim WG, Kim TY, Shong YK

The increased incidence of thyroid cancer is a worldwide phenomenon; however, the issue of overdiagnosis has been most prominent in South Korea. The age-standardized mortality rate of thyroid cancer in...
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Liver Involvement in Children with Alpha-1 Antitrypsin Deficiency: A Multicenter Study

Cakir M, Sag E, Islek A, Baran M, Tumgor G, Aydogdu S

PURPOSE: Alpha-1 antitrypsin deficiency (A1ATD) in one of the most common genetic causes of liver disease in children. We aimed to analyze the clinical characteristics and outcomes of patients with...
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Prognostic factors predicting survival rate over 10 years of patients with intrahepatic cholangiocarcinoma after hepatic resection

Ma CH, Hwang DW, Song KB, Kim SC, Shin SH, Lee JH

PURPOSE: Hepatic resection is considered as the optimal treatment for intrahepatic cholangiocarcinoma (IHCC); however, the survival rate after resection is low and the analysis of long-term (≥10 years) survivors is...
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BRCA1-associated protein 1 expression and prognostic role in prostate adenocarcinoma

Oh H, Lee YJ, Kang SG, Ahn B, Kim E, Chae YS, Lee Y, Lee JH, Kim CH

PURPOSE: As prostate cancer (PCa) is the second most commonly diagnosed cancer worldwide, finding novel markers for prognosis is crucial. BRCA1-associated protein 1 (BAP-1), a nuclear-localized deubiquitinating enzyme, has been...
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Survival prognoses of Heng intermediate-risk patients with metastatic renal cell carcinoma treated with immunotherapy or targeted therapy: A real-world, single-center retrospective study

Kim SH, Lee DE, Joung JY, Seo HK, Lee KH, Chung J

PURPOSE: This study aimed to compare progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS) in Heng intermediate-risk patients with metastatic renal cell carcinoma (mRCC) treated with first-line immunotherapy...
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