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Acquired Reactive Perforating Collagenosis as a Preceding Manifestation of Hodgkin's Lymphoma

Lee SY, Bang CH, Park YM, Lee JY, Lee JH

  • KMID: 2454375
  • Korean J Dermatol.
  • 2019 Jul;57(6):332-334.
A 40-year-old man presented with pruritic, multiple, variable-sized, erythematous umbilicated papules on the trunk and both extremities for 4 months. He was diagnosed with Hodgkin's lymphoma (stage IIA) after histopathologic...
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Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1Pâ‚‚) Attenuates Bleomycin-Induced Pulmonary Fibrosis

Park SJ, Im DS

Sphingosine 1-phosphate (S1P) levels are often found to be elevated in serum, bronchoalveolar lavage, and lung tissue of idiopathic pulmonary fibrosis patients and experimental mouse models. Although the roles of...
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Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells

Jang S, Ryu SM, Lee J, Lee H, Hong SH, Ha KS, Park WS, Han ET, Yang SR

BACKGROUND: Idiopathic pulmonary fibrosis involves irreversible alveolar destruction. Although alveolar epithelial type II cells are key functional participants within the lung parenchyma, how epithelial cells are affected upon bleomycin (BLM)...
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Efficacy of Percutaneous Sclerotherapy in Low Flow Venous Malformations - A Single Center Series

Ahmad S

PURPOSE: We analyzed results of percutaneous sclerotherapy for venous malformations (VMs) in head, neck and extremities. MATERIALS AND METHODS: Thirty-five patients with head and neck and extremities VM treated by sclerotherapy...
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The Effects of Retinoic Acid and MAPK Inhibitors on Phosphorylation of Smad2/3 Induced by Transforming Growth Factor β1

Lee SH, Shin JH, Shin MH, Kim YS, Chung KS, Song JH, Kim SY, Kim EY, Jung JY, Kang YA, Chang J, Park MS

BACKGROUND: Transforming growth factor β (TGF-β), retinoic acid (RA), p38 mitogen-activated protein kinase (MAPK), and MEK signaling play critical roles in cell differentiation, proliferation, and apoptosis. We investigated the effect...
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Solo Reduced Port Laparoscopic Left Lateral Sectionectomy

Choi Y, Han HS, Yoon YS, Cho JY, Kim S, Hyun IG, Kim KH

Laparoscopic approach for left lateral sectionectomy became the standard procedure. With increasing demand for minimizing of the access ports and with the advancement in surgical technique, reduced port laparoscopic surgery...
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A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals

Kim HR, Shin DY, Chung KH

Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011. “Omic”...
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Treatment of Tongue Lymphangioma with Intralesional Combination Injection of Steroid, Bleomycin and Bevacizumab

Hwang J, Lee YK, Burm JS

Lymphangioma is a congenital malformed lymphatic tumor that rarely involves the tongue. In our clinic, a 10-year-old female presented with lymphangioma circumscriptum involving the right two-thirds of the tongue. We...
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Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT

Adams HJ, de Klerk J, Regelink J, Heggelman , Dubois SV, Kwee TC

A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A...
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A novel clinicopathological analysis of early stage ovarian Sertoli-Leydig cell tumors at a single institution

Nam SM, Kim JW, Eoh KJ, Kim HM, Lee JY, Nam EJ, Kim S, Kim SW, Kim YT

OBJECTIVE: To evaluate the clinical and pathologic characteristics of patients who were diagnosed with ovarian Sertoli-Leydig cell tumors (SLCTs) in a single institution. METHODS: The medical records of 11 patients who...
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Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice

Choi SM, Jang AH, Kim H, Lee KH, Kim YW

Metformin has anti-inflammatory and anti-fibrotic effects. We investigated whether metformin has an inhibitory effect on bleomycin (BLM)-induced pulmonary fibrosis in a murine model. A total of 62 mice were divided...
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Role of ¹⁸F-FDG PET-CT in Monitoring the Cyclophosphamide Induced Pulmonary Toxicity in Patients with Breast Cancer: 2 Case Reports

Taywade SK, Kumar R, Bhethanabhotla S, Bal C

Drug induced pulmonary toxicity is not uncommon with the use of various chemotherapeutic agents. Cyclophosphamide is a widely used chemotherapeutic drug in the treatment of breast cancer. Although rare, lung...
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Human Adipose-derived Mesenchymal Stem Cells Attenuate Early Stage of Bleomycin Induced Pulmonary Fibrosis: Comparison with Pirfenidone

Reddy M, Fonseca L, Gowda S, Chougule B, Hari A, Totey S

BACKGROUND AND OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible, invariably fatal fibrotic lung disease with no lasting option for therapy. Mesenchymal stem cells (MSCs) could be a promising...
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Increased Cellular NAD⁺ Level through NQO1 Enzymatic Action Has Protective Effects on Bleomycin-Induced Lung Fibrosis in Mice

Oh GS, Lee SB, Karna A, Kim HJ, Shen A, Pandit A, Lee S, Yang SH, So HS

BACKGROUND: Idiopathic pulmonary fibrosis is a common interstitial lung disease; it is a chronic, progressive, and fatal lung disease of unknown etiology. Over the last two decades, knowledge about the...
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Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat

Li X, Shen Y, Lu Y, Yang J

Aldose reductase (AR) is known to play a crucial role in the mediation of diabetic and cardiovascular complications. Recently, several studies have demonstrated that allergen-induced airway remodeling and ovalbumin-induced asthma...
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Treatment of Verruca Vulgaris in Both External Auditory Canals Using Bleomycin Injections

Lee JH, Burm JS, Yang WY, Kang SY, Byun SW

Verruca vulgaris is caused by human papillomavirus (HPV) infections. Verruca in the external auditory canal (EAC) has rarely been reported. A previous case report introduced surgical excision as a treatment...
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Osteopontin Potentiates Pulmonary Inflammation and Fibrosis by Modulating IL-17/IFN-gamma-secreting T-cell Ratios in Bleomycin-treated Mice

Oh K, Seo MW, Kim YW, Lee DS

Lung fibrosis is a life-threatening disease caused by overt or insidious inflammatory responses. However, the mechanism of tissue injury-induced inflammation and subsequent fibrogenesis remains unclear. Recently, we and other groups...
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A Case of Sequential Lymphoma in an Human Immunodeficiency Virus-Infected Patient

Jung YN, Lee JR, Lee HS, Jin BS, Seo CI, Shin HS, Jung EJ

Rarely, two different histological types of lymphoma develop in the same person. Sequential lymphoma is defined as two different types of lymphoma occurring in the same person sequentially. A 47-year-old...
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Preliminary Study of Intralesional Bleomycin Injection for the Treatment of Genital Warts

Lee JY, Kim CW, Kim SS

No abstract available.
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Successful Treatment of Orbital Lymphangioma with Intralesional Bleomycin and Application of Continuous Negative Pressure

Lee KH, Han SH, Yoon JS

No abstract available.
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