Korean J Crit Care Med.  2015 Aug;30(3):171-175. 10.4266/kjccm.2015.30.3.171.

Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria

Affiliations
  • 1Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sbhong@amc.seoul.kr

Abstract

Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes. Endotoxin is considered to be a main element in the pathogenic induction of gram-negative bacterial sepsis. Polymyxin B hemoperfusion can remove endotoxin and is reported to improve clinical outcomes in patients with intra-abdominal septic shock, but its clinical efficacy for pneumonic septic shock remains unclear. Here, we report a case of a 51-year-old man with pneumonic septic shock caused by Pseudomonas aeruginosa, who recovered through polymyxin B hemoperfusion.

Keyword

endotoxin; hemoperfusion; polymyxin B; shock, septic

MeSH Terms

Cause of Death
Critical Illness
Gram-Negative Bacteria*
Hemoperfusion*
Humans
Middle Aged
Polymyxin B*
Polymyxins*
Pseudomonas aeruginosa
Sepsis
Shock, Septic*
Polymyxin B
Polymyxins
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