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Mitochondrial Quality Control in the Heart: New Drug Targets for Cardiovascular Disease

Oh CM, Ryu D, Cho S, Jang Y

Despite considerable efforts to prevent and treat cardiovascular disease (CVD), it has become the leading cause of death worldwide. Cardiac mitochondria are crucial cell organelles responsible for creating energy-rich ATP...
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Increasing Prevalence and Mortality of Asthma With Age in Korea, 2002–2015: A Nationwide, Population-Based Study

Lee E, Kim A, Ye YM, Choi SE, Park HS

PURPOSE: The prevalence of asthma is increasing globally as the world population increases; however, and the prevalence and mortality of asthma have not been extensively investigated. Also, the effects of...
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Distribution of Trauma Deaths in a Province of Korea: Is “Trimodal” Distribution Relevant Today?

Hwang K, Jung K, Kwon J, Moon J, Heo Y, Lee JC, Huh Y

PURPOSE: This study was designed to provide a basis for building a master plan for a regional trauma system by analyzing the distribution of trauma deaths in the most populous...
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Lung Pathology in Septic Shock with Leukopenia

Huh GY

Sepsis-related deaths are occasionally encountered in forensic practice. However, forensic pathologists are reluctant to use the terminology “sepsis” or “septic shock” as a cause of death because of the lack...
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Usefulness of Mast Cell Tryptase Analysis for Postmortem Diagnosis of Anaphylactic Shock

Park JP, Koo BY, Lee NW

Anaphylactic shock (AS) is a systemic and life-threatening type I hypersensitivity reaction and is often encountered at an autopsy. However, postmortem diagnosis of AS can be difficult due to non-specific...
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A Study on the Death Certificates and the Warrant of Seizure in Relation to the Death Certification System

Kim YS, Kim TE

The death certification system in a modern welfare state is of critical importance because it is related to the collection of national statistics for health policy, social security and social...
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Big Data Statistical Analysis of Facial Fractures in Korea

Park CH, Chung KJ, Kim TG, Lee JH, Kim IK, Kim YH

BACKGROUND: The big data provided by Health Insurance Review and Assessment (HIRA) contains data from nearly all Korean populations enrolled in the National Health Insurance Service. We aimed to identify...
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The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview

Maugeri A, Vinciguerra M

Cardiovascular disease (CVD), which is the leading cause of death worldwide, is strongly affected by diet. Diet can affect CVD directly by modulating the composition of vascular plaques, and indirectly...
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Positioning Metabolism as a Central Player in the Diabetic Heart

Mereweather LJ, Montes Aparicio CN, Heather LC

In type 2 diabetes (T2D), the leading cause of death is cardiovascular complications. One mechanism contributing to cardiac pathogenesis is alterations in metabolism, with the diabetic heart exhibiting increased fatty...
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Attenuated total reflection Fourier transform infrared as a primary screening method for cancer in canine serum

Macotpet A, Pattarapanwichien E, Chio-Srichan S, Daduang J, Boonsiri P

Cancer is a major cause of death in dogs worldwide, and the incidence of cancer in dogs is increasing. The attenuated total reflection Fourier transform infrared spectroscopic (ATR-FTIR) technique is...
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Chimeric Antigen Receptor T Cell Therapy: A Novel Modality for Immune Modulation

Yoon S, Eom GH

Cancer remains a leading cause of death, despite multimodal treatment approaches. Even in patients with a healthy immune response, cancer cells can escape the immune system during tumorigenesis. Cancer cells...
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Treatment of Isoniazid-Resistant Pulmonary Tuberculosis

Jhun BW, Koh WJ

Tuberculosis (TB) remains a threat to public health and is the leading cause of death globally. Isoniazid (INH) is an important first-line agent for the treatment of TB considering its...
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Effect of the Interaction Between Selenium and Zinc on DNA Repair in Association With Cancer Prevention

Yildiz A, Kaya Y, Tanriverdi O

Cancer is the most common cause of death worldwide. Annually, more than ten million new cancer cases are diagnosed, and more than six million deaths occur due to cancer. Nonetheless,...
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Risk Factors and Causes of Short-Term Mortality after Emergency Department Discharge in Older Patients: Using Nationwide Health Insurance Claims Data

Na S, Cho Y, Lim TH, Kang H, Oh J, Ko BS

BACKGROUND: The purpose of this study was to identify the risk factors and causes of short-term mortality after emergency department (ED) discharge in older patients. METHODS: This population-based cohort study used...
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Analysis of Errors on Death Certificate for Trauma Related Death

Chang JH, Kim SH, Lee H, Choi B

PURPOSE: This study was to investigate errors of death certificate (DC) issued for patients with trauma. METHODS: A retrospective review for DC issued after death related to trauma at a training...
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A Study on the Relationship between the Spatial Cluster Patterns of Male Suicide Rate and the Regional Characteristics in South Korea

Choi S, Lee KS

BACKGROUND: Since 2003, Korea has consistently shown the highest suicide rate among the Organization for Economic Cooperation and Development countries, and suicide remains the major cause of death. In particular,...
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Estimating Influenza-associated Mortality in Korea: The 2009–2016 Seasons

Hong K, Sohn S, Chun BC

OBJECTIVES: Estimating influenza-associated mortality is important since seasonal influenza affects persons of all ages, causing severe illness or death. This study aimed to estimate influenza-associated mortality, considering both periodic changes...
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Concordance between the underlying causes of death on death certificates written by three emergency physicians

Lee H, Kim SH, Choi B, Ock M, Park EJ

OBJECTIVE: This study was conducted to evaluate the concordance between the underlying causes of death (UCOD) on the death certificates written by three emergency physicians (EPs). We investigated errors on...
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Application of Artificial Intelligence in Lung Cancer Screening

Lee SM, Park CM

Lung cancer is a leading cause of deaths due to cancer, worldwide. At present, low-dose computed tomography (CT) is the only established screening method for reducing lung cancer mortality. However,...
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Lung Cancer Screening with Low-Dose CT: Current Status in Other Countries

Goo JM

Lung cancer is the leading cause of death from cancer worldwide. The most effective way to reduce lung cancer mortality is early detection and treatment. Two large randomized controlled trials...
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