J Korean Med Assoc.  2003 Jun;46(6):521-526. 10.5124/jkma.2003.46.6.521.

Genetic Test

• Choi JR

• KMID: 2183089
• DOI: http://doi.org/10.5124/jkma.2003.46.6.521

Abstract

The genetic test is a powerful diagnostic tool targeting DNA and RNA, now widely used not only in diagnosis of cancers, infectious disease, genetic disease, but also ABO genotyping, HLA typing, and forensic medicine. Even though a genetic test is of an important diagnostic value, the technical difficulty and expense make it difficult for it to completely replace the standard tests. As it is a test of high sensitivity, there is a possibility of misjudgment by errors in sample. Supplementary tests such as morphology analysis or tissue pathology may be helpful in such cases. The automation of molecular-genetic diagnostic methods such as PCR, DNA sequencing, and DNA chip will help genetic tests highlighted in laboratories in the near future.

Keyword

Genetic test; DNA; Molecular-genetic diagnostic methods

MeSH Terms

Automation
Communicable Diseases
Diagnosis
DNA
Forensic Medicine
Histocompatibility Testing
Oligonucleotide Array Sequence Analysis
Pathology
Polymerase Chain Reaction
RNA
Sequence Analysis, DNA
DNA
RNA