Korean J Thorac Cardiovasc Surg.  2006 Jun;39(6):449-455.

The Influence of Gender on the Long-term Outcome of Coronary Artery Bypass Surgery

• Choi JB
• Lee MK
• Cha BK
• Lee SY

Abstract

BACKGROUND: Female sex was known to be a risk factor for mortality after coronary bypass grafting (CABG), and women showed higher in-hospital mortality than men. MATERIAL AND METHOD: Between 1992 and 1996, 147 consecutive patients (98 men and 49 women) undergoing CABG were included in the study. Most patients had undergone CABG with left internal thoracic artery and saphenous vein under cardiopulmonary bypass. We examined the influence of gender on survival after CABG and looked for risk factors for survival. RESULT: There was no in-hospital mortality in women, but 3 death (3.0%) in men. During the mean follow-up period of 138.5+/-23.0 months, mortality was lower in women than in men (20.4% vs 44.9%, p=0.004), and the most common cause of death in women was chronic renal failure (40%). Survival in women at 1, 5, 10, and 14 years was 100%, 98.0+/-2.0%, 81.2+/-5.6%, and 78.4+/-6.1%, respectively, which was better than in men (p=0.004). Although preoperative left ventricular ejection fraction was higher in women than in men, this did not affect early and long-term survival difference between two sexes (p=0.15). Risk factor for long-term survival in women was diabetes (p=0.033) and in men number of diseased coronary artery (p=0.006).
CONCLUSION
Long-term survival after CABG was better in women than men. Risk factor for long-term survival in women was morbid disease rather than cardiac disease.

Keyword

Coronary artery bypass; Women; Survival analysis; Risk assessment

MeSH Terms

Cardiopulmonary Bypass
Cause of Death
Coronary Artery Bypass*
Coronary Vessels*
Female
Follow-Up Studies
Heart Diseases
Hospital Mortality
Humans
Kidney Failure, Chronic
Male
Mammary Arteries
Mortality
Risk Assessment
Risk Factors
Saphenous Vein
Stroke Volume
Survival Analysis
Transplants