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Generation and characterization of regulatory macrophages for xenotransplantation

Hoang TX, Kim JY, Pham HL, Nguyen NL, Jeong J, Kim YJ, Tran TM, Kim MH, Lee MK

The outstanding role of regulatory macrophages (Mregs) in promoting immunomodulation allowed the clinical application of Mregs-based therapies for controlling unwanted immune responses, especially in the field of transplantation. The major...
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Real-World Accuracy of a SARS-CoV-2 Rapid Diagnostic Tests in the Republic of Korea

Kweon OJ, Kim HR, Lee MK, Lim YK

Antigen rapid diagnostic tests (RDTs) became the most important tool for the diagnosis of the coronavirus disease 2019 (COVID-19), however there have been very few evaluations of the accuracy of...
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Actual situation and prescribing patterns of opioids by pain physicians in South Korea

Kim MJ, Kim JY, Lim YH, Hong SJ, Jeong JH, Choi HR, Park SK, Kim JE, Lee MK, Kim JH

Background: Use of opioids for chronic intractable pain is increasing globally, and their proper use can improve patients’ quality of life. In contrast, opioid use disorders, such as abuse or...
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Changes of Causative Organism and Antimicrobial Resistance in Urinary Tract Infections After the COVID-19

Choi YH, Tae JH, Lee MK, Kim TH

Purpose: During the coronavirus disease 2019 (COVID-19) pandemic, several studies reported changes in the distribution of microorganisms that cause major legal, respiratory, and gastrointestinal infectious diseases and increases in the...
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Microorganisms Isolated from Urine Cultures and Their Antimicrobial Susceptibility Patterns at a Commercial Laboratory during 2018-2020

Kwak B, Hong J, Bae HG, Park YS, Lee MK, Lee K, Lee KR

Background: Antimicrobial resistance of bacterial pathogens that cause urinary tract infections is a leading concern in Korea. This study analyzed the urine culture results and antimicrobial susceptibility trend in different...
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Conceptual Analysis of Health Behavior in Tuberculosis Patients

Kim HJ, Lee MK

Purpose: Health behavior is important for the treatment of tuberculosis patients. This study aims to clarify the concept of health behavior in tuberculosis patients. Methods: We used Rodger's evolutionary concept analysis...
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Positivity of Rapid Antigen Testing for SARS-CoV-2 With Serial Followed-up Nasopharyngeal Swabs in Hospitalized Patients due to COVID-19

Kweon OJ, Lee JH, Choi YS, Kim BS, Lim YK, Lee MK, Park JH, Park JY, Kim SH

Despite the accuracy of nucleic acid amplification tests (NAATs), rapid antigen tests (RATs) for severe acute respiratory syndrome coronavirus-2 are widely used as point-of-care tests. A total of 282 pairs...
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Issues pertaining to Mg, Zn and Cu in the 2020 Dietary Reference Intakes for Koreans

Chung HY, Lee MK, Kim W, Choi MK, Kim SH, Kim E, Kim MH, Ha JH, Lee H, Bae YJ, Kwun IS

In the current years, it has now become necessary to establish standards for micronutrient intake based on scientific evidence. This review discusses issues related to the development of the 2020...
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Comparative Analysis of Cutaneous Fungi in Atopic Dermatitis Patients and Healthy Individuals

Choi Y, Park KY, Han HS, Lee MK, Seo SJ

Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease triggered by diverse factors. Microbes are one of the crucial risk factors for AD development or exacerbation. However, the...
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Development of In Vitro Co-Culture Model to Mimic the Cell to Cell Communication in Response to Urban PM2.5

Roh YJ, Noh HH, Koo NY, Shin SH, Lee MK, Park KY, Seo SJ

Background: Airborne particulate matter (PM), a widespread air contaminant, is a complex mixture of solids and aerosols composed of particles suspended in the air. PM is associated with inflammatory responses...
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Factors Associated with Body Weight Gain among Korean Adults during the COVID-19 Pandemic

Hur YI, Huh Y, Lee JH, Lee CB, Kim BY, Yu SH, Kim JH, Kim JW, Kim HM, Lee MK, Hong JH, Choi D, Bae J, Lee KH, Kim JY

Background: Obesity is of grave concern as a comorbidity of coronavirus disease 2019 (COVID-19). We examined the factors associated with weight gain among Korean adults during the COVID-19 pandemic. Methods: We...
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The Role of Collagen VI α6 Chain Gene in Atopic Dermatitis

Jung HJ, Heo WI, Park KY, Lee MK, Ahn JY, Park MY, Seo SJ

Background: In a previous study, we carried out whole-exome sequencing to identify genetic variants associated with early onset atopic dermatitis (AD) in Koreans and found that collagen VI α6 chain...
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A Study on the Refusal of National Examination for Medical Students: Focusing on the Signaling Game Theory

Hyeon SH, Kim DY, Lee MK

Background: Conflict in the medical world in 2020 led to the rejection of the national examination for doctors. This study explained the process until the end of the national test...
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Xanthone and Flavonoid Derivatives from the Leaves of Maclura tricuspidata with Antioxidant and Anti-tyrosinase Activity

Jo YH, Lee S, Ryu SH, Yeon SW, Turk A, Hwang BY, Lee MK

Masclura tricuspidata, also called as Cudrania tricuspidata, is one of the most common Moraceae family plants in East Asia. Its trivial name follows mulberry due to the similar morphology. Investigation...
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Hip Fracture Management during the COVID-19 Pandemic in South Korea

Chung JW, Ha YC, Lee MK, Kim JH, Park JW, Koo KH

Background: The purpose of this study was to introduce a screening system for coronavirus disease 2019 (COVID-19), to evaluate the overall orthopedic management in hip fracture patients during the COVID-19...
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Effectiveness and Biocompatibility of Decellularized Nerve Graft Using an In Vivo Rat Sciatic Nerve Model

Kim DH, Shin SH, Lee MK, Lee JJ, Kim JK, Chung YG

BACKGROUND: Decellularized nerve allografting is one of promising treatment options for nerve defect. As an effort to develop more efficient nerve graft, recently we have developed a new decellularization method...
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Optimization of Cultivation and Extraction Conditions of Pupae-Cordyceps for Cordycepin Production

Turk A, Kim BS, Ko SM, Yeon SW, Ryu SH, Kim YG, Hwang BY, Lee MK

Cordycepin is a characteristic bioactive compound of Cordyceps militaris with various beneficial effects. Cordyceps grows on both grains and insects, and the content of cordycepin varies depending on the cultivation...
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Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients

Ahn J, Lee MK, Lee JH, Sohn SY

Background: Data on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, including overt thyrotoxicosis and suppression of thyroid function. We aimed to evaluate the thyroid hormone...
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Ten-Year Prevalence Trends of Phenotypically Identified Community-Associated Methicillin-Resistant Staphylococcus aureus Strains in Clinical Specimens

Yu SH, Lee JH, Kim MC, Choi SH, Chung JW, Lee MK

Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains were first detected in hospitals in Korea between the late 2000s and early 2010s. However, there is limited information regarding the prevalence of CA-MRSA...
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Weight change and microvascular outcomes in patients with new-onset diabetes: a nationwide cohort study

Koh ES, Han KD, Kim MK, Kim ES, Lee MK, Nam GE, Kwon HS

Background/Aims: Because weight control is important in treatment of type 2 diabetes, it is essential to understand the associations between weight change and the risk of microvascular complications among patients...
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